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1.
Xin Gen Luo Hai Sheng Chen Shuang Liang Mao Huang Wei Dong Xuan Li Jin College of Pharmacy Second Military Medical University Shanghai China Department of Pharmacy Guangzhou Military General Hospital Guangzhou China Center of New Drug Evaluation Institute of Basic Medical Sciences Second Military Medical University Shanghai China 《中国化学快报》2007,18(6):697-699
Six indole alkaloids were isolated from the stems of Ervatamia yunnanensis. Among them, yunnanensine (I) is new. The other five are known alkaloids, namely: 19,20-E-vallesamine (II), 19s-heyneanine (HI), ibogaine (IV), ibogamine (V), coronaridine (VI). The structural elucidation of the alkaloids was based on spectral means. 相似文献
2.
ErvalanIiaYunnanensiSTsianghasbeenusedasafolkmedicineinChinaforthetreatmentofhypertensi0n'.Aspart0fourc0ntinuingpr0gramonthestudyofplant-derivedbioactivecomp0unds,thechemicaIconstituents0fE.yunnanensI1vgrowinginYunnanwereinvestigated.Intheprevi0uspaper,werep0rtedthestructuresofind0lealkal0ids;l9S-hydr0xy-tacamine,tabernaemontanine,l7-demethoxy-c0rynoxineB,l7-demethoxy-hydr0c0rynoxineB,20-epi-ervatamine,19,2O-dehydroervatamine,includinganewone,l9S-hydroxy-16-epi-tacaminefr0mthisspecies'.T… 相似文献
3.
Evratamia hainanensis Tsiang, is distributed in the mountain and forest regions of 100-500 metres height in the southern part of China. Its root has been used for the treatment of stomachache, dysentery, rheumatic arthritis, hypertension and virus hepatit… 相似文献
4.
Shuang LIANG Xin Gen LUO Hai Sheng CHEN? Xiao Dong ZHANG Mao HUANG Wen Yong LIU College of Pharmacy Second Military Medical University Shanghai Department of Pharmacy Guangzhou Military General Hospital Guangzhou Center of New Drug Evaluation Institute of Basic Medical Sciences Second Military Medical University Shanghai 《中国化学快报》2006,(6)
The non-alkaloid chemical constituents, which were isolated from the stems of Ervatamia yunnanensis Tsiang (Apocynaceae), have been reported in previous paper 1. As a part of our continuing research on the isolation of active compounds for anti-addictive … 相似文献
5.
《Magnetic resonance in chemistry : MRC》2002,40(7):474-476
A new alkaloid, 15‐β‐stemmadenine, was isolated from the fruits of Tabernaemontana heyneana Wall. from the ethanolic extract. The complete 1H and 13C NMR assignments of the compound were carried out using COSY, HMQC and HMBC. Stereochemistry at C‐15 and C‐16 was established using ROESY and temperature‐dependent 1H NMR studies. Copyright © 2002 John Wiley & Sons, Ltd. 相似文献
6.
Valdecoxib is a new anti-inflammatory drug that is highly selective for inhibition of the inducible form of cyclooxygenase
(COX-2). In the present study, biotransformation of valdecoxib was investigated in cell cultures of five medicinal plants,
viz., Catharanthus roseus, Azadirachta indica, Capsicum annuum, Ervatamia heyneana, and Nicotiana tabacum. Identification of the biotransformed products was carried out by using high-performance liquid chromatography coupled with
diode array detection and liquid chromatography–tandem mass spectrometry analysis. All the cultures transformed valdecoxib
into more polar compounds, and C. roseus also produced one unknown compound that is less polar than the substrate. The reactions performed by these plant cell cultures
include hydroxylation, methylation, and demethylation. Optimization studies were performed to investigate the effect of the
day of extraction and substrate concentration on biotransformation. 相似文献
7.
Zhao Hui YUAN Li Jun HAN Xiao FAN Ming MA Da Yong SHI Jian Gong SHI 《中国化学快报》2006,17(9):1205-1208
Gymnogongrus flabelliformis Hav. is a red alga belonging to Phyllophoraceae family (Gigartinales order), and widely distributed along the coast of China Sea1. Up to now no chemical constituent of this species has been reported. As a part of our program to assess systematically the chemical and biological diversity of seaweeds distributed in China Sea2-4, the red alga G. flabelliformis was collected along the coast of Qingdao, Shandong Province. We report herein the isolation and structural… 相似文献
8.
Shuang LIANG Xin Gen LUO Hai Sheng CHEN Xiao Dong ZHANG Mao HUANG Wen Yong LIU 《中国化学快报》2006,17(6):783-786
Six indole alkaloids were isolated from the stems of Ervatamia yunnanensis. Among them, 10-hydroxy-19, 20-dihydroisositsirikine (I) is new. The other five are known alkaloids, namely: matrine (Ⅱ), 19, 20-dihydroisositsirikine (Ⅲ), 19-s-voacangarine (Ⅳ), 1 l'-methoxyl-19s- heyneanine (Ⅴ), conodurine (Ⅵ). The structural elucidation of the alkaloids was based on spectral means. 相似文献
9.
Shuang Liang Hai‐Sheng Chen Yun‐Heng Shen Li Jin Wei‐Dong Zhang 《Helvetica chimica acta》2007,90(8):1467-1470
Flabelliformides A ( 1 ) and B ( 2 ), containing a novel C20 indole core, have been isolated from the stems of Ervatamia flabelliformis. The structures of 1 and 2 were elucidated on the basis of spectral analysis and X‐ray crystallography. 相似文献
10.