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人小肠癌转移腹水细胞系HICMA的核型分析 总被引:2,自引:0,他引:2
采用TdR同步化的方法,分析了人小肠癌转移腹水细胞系HICMA的核型,发现该细胞系染色体数目主要分布于52~56条之间,众数为54条;染色体畸变复杂,在近50%的分裂相中存在一条端着丝粒染色体,GTG显带表明该染色体为正常5号染色体去掉整个短臂而成.对染色体畸变与细胞癌变的关系进行了讨论. 相似文献
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采用扫描电镜观察了大鲵精子的形状,受精过程中卵壳膜的变化,及精子入卵的过程.人工催产的精子头部具有棒状和辣椒状两种形状.卵壳膜随着受精时间的变化而出现皱褶、沟与嵴,受精完毕,皱褶消失.大鲵属于多精入卵,精、卵相遇60s,精子接触卵膜,授精75s精子头部一半进入卵内.授精90s精子头部和颈部完全进入卵内,但精子尾部留在卵膜外面;授精2min,受精完毕. 相似文献
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Two New Cyclic Tetrapeptides of Streptomyces rutgersensis T009 Isolated from Elaphodus davidianus Excrement
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Shu‐Quan Li Ya‐Bin Yang Xue‐Qiong Yang Yi Jiang Zhen‐Jie Li Xiao‐Zhan Li Xiu Chen Qi‐Lin Li Shao‐Huan Qin Zhong‐Tao Ding 《Helvetica chimica acta》2016,99(3):210-214
Two new cyclic tetrapeptides, cyclo(l ‐Val‐l ‐Leu‐l ‐Val‐l ‐Ile) ( 1 ) and cyclo(l ‐Leu‐l ‐Leu‐l ‐Ala‐l ‐Ala) ( 2 ), and 15 known compounds, cyclo(Gly‐l ‐Leu‐Gly‐l ‐Leu) ( 3 ), cyclo(l ‐Ser‐l ‐Phe) ( 4 ), cyclo(l ‐Leu‐l ‐Ile) ( 5 ), cyclo(l ‐Tyr‐l ‐Phe) ( 6 ), cyclo(Gly‐l ‐Trp) ( 7 ), cyclo(l ‐Leu‐l ‐Tyr) ( 8 ), cyclo(Gly‐l ‐Phe) ( 9 ), cyclo(l ‐Phe‐trans‐4‐hydroxy‐l ‐Pro) ( 10 ), cyclo(l ‐Leu‐l ‐Leu) ( 11 ), cyclo(l ‐Val‐l ‐Phe) ( 12 ), cyclo(l ‐Val‐l ‐Leu) ( 13 ), cyclo(l ‐Ile‐l ‐Ile) ( 14 ), cyclo(l ‐Tyr‐l ‐Tyr) ( 15 ), turnagainolide A ( 16 ), and bacimethrin ( 17 ) were isolated from the fermentation broth of Streptomyces rutgersensis T009 obtained from Elaphodus davidianus excrement. Their structures were identified on the basis of spectroscopic analysis. Meanwhile, the absolute configurations of the amino acid residues of compounds 1 and 2 were determined by advanced Marfey method. Compound 3 was obtained from a natural source for the first time. The X‐ray single crystal diffraction data of bacimethrin ( 17 ) were also reported for the first time. Compounds 1 – 17 exhibited no antimicrobial activities with the MICs > 100 μg/ml. 相似文献
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