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Su Yeon Kim Hwa Jung Roh Da Young Seo Ji Yeon Ryu Junseong Lee Jae Nyoung Kim 《Tetrahedron letters》2017,58(10):914-918
Base-catalyzed domino reaction between N-methylisatin and methyl propiolate afforded four diastereomeric dispiro-1,3-dioxolane bisoxindoles. The reaction mechanism involved sequential 1,2-addition of acetylide anion to the carbonyl group of isatin, 1,2-addition of the resulting oxyanion to a second molecule of isatin, and the final 5-exo-dig cyclization process. 相似文献
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