求解中短半径弯螺杆钻具的纵横弯曲法

介绍了一种求解中短半径($K=1^\circ$/m$ \sim 3^\circ$/m)弯螺杆 钻具的纵横弯曲法, 以指导弯螺杆钻具的设计和使用. 采用变刚度梁柱理论, 并应用等效载荷法对具有初始结构弯角的梁柱进行等效处理, 根据钻具组合支座连续条件及 边界条件建立了中短半径水平井造斜螺杆钻具组合的力学模型, 进而求得钻头侧向力, 依此 预测弯螺杆钻具的造斜能力. 这种分析方法得到了成功应用.     

Chemical composition and antioxidant activity of Borago officinalis L. leaf extract growing in Algeria

The aqueous and hydroalcoholic extracts of borage (Borago officinalis) leaves from Annaba region (Algeria) were preliminary analyzed for their phenolic profile (total phenolics, total flavonoids, total flavonols, total tannins and total anthocyanins). These extracts were evaluated for their antioxidant properties by different methods such as DPPH radical scavenging, test NBT and total antioxidant activity. The two extracts have exhibited a high antiradical capacity. Indeed, the ethanolic extract showed the lower IC50 values and the highest amount of phenolics (94.09 ± 1.72 mg gallic acid/g dry extract). Using LC-MS/MS analysis, it was possible to identify phenolic acids, flavonoids, sterol and for the first time oleuropein was identified in the aqueous extract of the plant. The obtained results have demonstrated that phenolic compounds are the major contributor to the antioxidant activity of plants.     

THE PHOTOTOXIC EFFECT OF BENOXAPROFEN AND ITS ANALOGS ON HUMAN ERYTHROCYTES AND RAT PERITONEAL MAST CELLS

Abstract— Benoxaprofen [2-(4-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid] is a phototoxic non-steroidal anti-inflammatory agent. Irradiation of human erythrocytes in the presence of benoxaprofen (8 μ M ) and oxygen resulted in rapid cell lysis which began after 10 min and was complete within 30 min. While photohemolysis was also observed under anerobic conditions, its onset was delayed for more than 20 min and it took nearly 100 min for complete lysis to occur. Photohemolysis was also delayed by butylated hydroxyanisole but was unaffected by reduced glutathione. 1,4-diazabicyclo[2.2.2]octane, D₂O. β-carotene, or superoxide dismutase. The main photoproduct of benoxaprofen, 2-(4-chlorophenyl)-5-ethylbenzoxazole, was almost as effective in causing photohemolysis as benoxaprofen itself. In the presence of UV irradiation, benoxaprofen (10 (μ M ) caused the degranulation of rat peritoneal mast cells and the release of histamine. The release of mast cell histamine may provide a reasonable explanation for the urticarial response to benoxaprofen and irradiation seen in human subjects.     

铥、镱、钇对铽-苯甲酰异羟肟酸配合物荧光的增强作用

本文通过对Tm（Ⅲ）-苯甲酰异羟肟酸（BHA）体系的发射光谱和激发光谱分析,研究了铥、镱和钇离子对Tb-BHA体系的发光性质的增强作用。测得了增敏离子的最佳浓度分别为1.8×10-4mol/L(Tm3+),1.5×10-4mol/L(Yb3+)和2.0×10-4mol/L(Y3+).并对RE-BHA（RE=Tm,Yb,Y和Tb）的固态配合     

旋转导向系统底部钻具组合力学计算新方法

底部钻具组合(Bottom Hole Assembly, BHA)的力学计算是进行旋转导向系统钻具组合设计和井眼轨迹控制的基础．本文在纵横弯曲法、加权余量法和有限元法的基础上,提出了一种基于管柱单元组合的BHA力学求解方法．该方法以保持微分方程特解相同的条件作为管柱单元划分依据,对底部钻具组合进行单元划分;将管柱单元的挠曲线通解替代传统加权余量法的试函数,结合单元节点类型和组合关系,构建出包含边界条件和通解系数的线性方程组．对于边界条件未知问题,以支点反力符号条件为约束条件,以挠曲线越界程度、切点处弯矩平衡条件为目标函数,建立了以边界条件未知量为变量的多目标优化数学模型．应用多目标优化算法求解出边界变量,进而得出通解系数;最后,得出管柱单元内各点位移和载荷．以推靠式旋转导向系统BHA力学计算为案例,对比本文方法与加权余量法的计算结果,发现两者计算结果相差较小,表明本文方法可用于旋转导向系统底部钻具组合的力学计算．     

Simultaneous determination of butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) in food samples using a carbon composite electrode modified with Cu3(PO4)2 immobilized in polyester resin

A simple electrochemical method was developed for the single and simultaneous determination of butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) in food samples using square-wave voltammetry (SWV). A carbon composite electrode modified (MCCE) with copper (II) phosphate immobilized in a polyester resin was proposed. The modified electrode allowed the detection of BHA and BHT at potentials lower than those observed at unmodified electrodes. A separation of about 430 mV between the peak oxidation potentials of BHA and BHT in binary mixtures was obtained. The calibration curves for the simultaneous determination of BHA and BHT demonstrated an excellent linear response in the range from 3.4 × 10⁻⁷ to 4.1 × 10⁻⁵ mol L⁻¹ for both compounds. The detection limits for the simultaneous determination of BHA and BHT were 7.2 × 10⁻⁸ and 9.3 × 10⁻⁸ mol L⁻¹, respectively. In addition, the stability and repeatability of the electrode were determined. The proposed method was successfully applied in the simultaneous determination of BHA and BHT in several food samples, and the results obtained were found to be similar to those obtained using the high performance liquid chromatography method with agreement at 95% confidence level.     

旋转导向钻具组合力学分析

旋转导向系统代表了当今定向钻井的先进水平,是井眼轨道控制技术的发展方向. 为了解决旋转导向钻井轨道控制问题,进行了旋转导向钻具组合(rotary steering bottom hole assembly, RS-BHA) 力学分析. 应用纵横弯曲法建立了典型的柔性RS-BHA 三维力学分析模型,得到了钻头侧向力和导向参数间的相互关系,进而根据极限曲率法可预测旋转导向工具的造斜能力,并计算设计井眼轨道需要的导向参数. 通过力学分析,可以优化RS-BHA,了解井眼轨道控制规律,为旋转导向工具设计和定向钻井自动控制提供理论依据.     

反相高效液相色谱法测定口香糖中的抗氧化剂BHA

采用 Zorbax XDB- C18柱 (4 .6× 15 0 mm) ,以乙腈和水按 6 0∶ 4 0的配比作流动相 ,流量为 1m L /min,柱温 30℃ ,检测波长 2 80 nm,建立了一种用反相高效液相色谱测定口香糖中 BHA的方法。检出限为0 .15 mg/kg,回收率在 83%— 10 1%之间 ,相对标准偏差小于等于 7.5 %。本法具有操作简便 ,灵敏、准确 ,重现性好等优点。适用于口香糖中 BHA的定量分析。     

BeAl_6O_(10)晶体中单体铬和铬离子对的窄线发光

BeAl_6O_(10):Cr的荧光谱由宽带和七条窄线组成.在室温下,宽带和窄线发光的衰减时间极不相同.本文根据线强度的温度关系、浓度关系推论,三条窄而强的荧光线来自两种单体铬中心.另有两条稍宽的线来自铬离子对中心.宽带发射与这些窄线发射没有象BeAl_2O_4:Cr中那样的联系.     

流动注射化学发光法测定食品中叔丁基茴香醚与2,6-二叔丁基对甲酚

基于叔丁基茴香醚(BHA)与2,6 二叔丁基对甲酚(BHT)与铬(Ⅵ)的还原反应,产生的铬(Ⅲ)催化Luminol(鲁米诺) 过氧化氢化学发光体系的研究,结合流动注射技术,建立了一种高灵敏度的快速测定BHA与BHT的新方法。方法的线性范围为2.0×10-9～4.0×10-5g·ml-1和2.8×10-9～1.0×10-5g·ml-1,检出限为6.0×10-10g·ml-1和8.0×10-10g·ml-1,相对标准偏差为1.2%和1.4%(1.0×10-7g·ml-1BHA和BHT,n=11)。方法应用于食品中痕量BHA和BHT的测定,结果满意。