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Jan A. Rojas Stütz 《Tetrahedron letters》2004,45(3):509-513
A 5′-amino-2′,5′-dideoxyguanosine phosphoramidite building block for DNA synthesis was prepared from 2-N-(dibutylformamidino)-2′-deoxyguanosine in four steps and 68% overall yield. Two of the three steps of the conversion from the 5′-alcohol to the monomethoxytritylamine were performed in the same flask. 相似文献
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