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A new cytotoxic pyrrolidinoindoline diketopiperazine dimer, cristatumin E (1), was isolated from the fermentation broth of the algal fungus Eurotium herbariorum HT-2 associated with the marine algae, Enteromorpha prolifera. The structure was determined by spectroscopic analyses and Marfey's amino acid analysis. Cristatumin E (1) showed cytotoxicity against K562 tumor cell line and antibacterial activity against Enterobacter aerogenes and Escherichia coli with IC50 and MIC values of 8.3, 44.0 and 44.0 μmol/L, respectively. 相似文献
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利用细菌在生长过程中会合成各种有关代谢的酶类(预成酶)这一原理,采用自行设计的快速微量生化反应方法进行肠杆菌属的鉴定,以《伯杰氏系统细菌学鉴定手册》第八版为标准,建立了肠杆菌科分属的生化鉴定试剂盒,在实验验证过的菌株中与常规方法符合率达百分之百。 相似文献
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