Effects of Pre-exposure of Mouse Pituitary with Low-dose ^60Co γ-ray on Male Reproductive Endocrine Capacity Induced by Subsequent High-dose Irradiation

To investigate the effects of pre-exposure of mouse pituitary with low-dose ^60Co γ-ray on male reproductive endocrine capacity induced by subsequent high-dose irradiation, the pituitary of the B6C3F1 hybrid strain male mice were irradiated with 0.05 Gy of ^60Co γ-ray as the pre-exposure dose (D1), and were then irradiated with 2 Gy of ^60Co γ-ray as challenging irradiation dose (D2) at 4 h after per-exposure. Pituitary gonadotroping hormones --follicle-stimulating hormone (FSH) and luterinzing hormone (LH), serum testosterone, testis weight and sperm count were measured at 35th day after irradiation.     

论数——孔子和弟子们的数学课 弹簧狗狗

正大家还记得去年我向你们介绍过的卢声怡老师的数学趣味故事集《论数——孔子和弟子们的数学课》吗?现在",论数"来到《数学大王》啦!这本书用子卢(孔子的一个学生)的视角,讲述了古代孔子办学教学生们学数学的趣味故事。来,我们一起来看故事吧!这些都是新的故事,而不是书上的故事哦!"孔老师!我爸爸……"子路从教室外面探进头来,一看只有我在擦黑板,连忙改口,"咦?子卢,孔老师呢?"我拍拍手上的白灰,说:"回书房去了,你有什么事呀?"     

染色体的三维重组

欧洲的研究者观察到，在老鼠胚胎发育的初期和随后的发育过程中，染色体会在细胞核周围跳动。     

Functional Mechanism of Resveratrol in Inhabiting Growth of Cells ls174t and Its Mechanism in Subcutaneously Transplanted Tumor of Nude Mice

To explore the functional mechanism of Resveratrol against colon cancer cells Is174t and the growth of colon cancer tissue of tumor-bearing mice,MTT method was used to observe the functions of resveratrol for inhibition against cells ls174t in vitro.Transmission electron microscope was used to observe the cell apoptosis.FCM assay was performed to measure the change of the cell apoptosis rate and of cell cycle,RT-PCR method was used to detect the expressions of bc1-2 and bax mRNA.Western blot method was used to detect the expressions of bc1-2 and bax protein.Cells isi74t were transplanted subcutaneously to nude mice to observe the effect of resveratrol on the growth of subcutaneously transplanted tumor.RT-PCR method was used to detect the expressions of bc1-2 and bax mRNA in the tumor tissue.Western blot method was used to detect the expressions of bc1-2 and bax protein in the tumor tissue.Resveratrol has an effect of inhibiting proliferation of cells ls174t in vitro(P<0.01).It is able to induce the apoptosis of cells Is174t,causing the decrease in the expression of bc1-2 and the increase in the expression of bax.Resveratrol could inhibit the growth of subcutaneously transplanted tumor of nude mice(P<0.05),causing the decrease in the expression of bc1-2 and the increase in the expression of bax.Resveratrol can inhibit the growth of cells 174t and the growth of subcutaneously transplanted tumor.The mechanism is possibly related to the induction of the cell apoptosis and the regulation of bc1-2/bax expression.     

老鼠钻得过吗

在离我们很远很远的地方,有一片辽阔的大海,大海中央有一座面积挺大的岛屿。岛上没有人类居住,却有着种娄繁多的动植物和小精灵。     

老鼠血清中苯扎贝特的HPLC-MS法测定

建立一种简便、快速、灵敏的高效液相色谱-质谱联用测定老鼠血清中苯扎贝特的方法。 采用Gemini C18色谱柱;流动相：V(乙腈)∶V(甲醇)∶V(水)=60∶15∶25(0.03%甲酸水溶液);柱温35 ℃,流速0.3 mL/min;紫外吸收波长为235 nm;进样量5 μL。 质谱采用电喷雾电离负离子模式,用于定量分析的离子分别为[M-H]- m/z 359.65→273.70(苯扎贝特)和[M-H]- m/z 212.95→127.08(氯贝酸)。 对苯扎贝特检测的线性范围为0.073~7.884 mg/L,r=0.9995。 得到苯扎贝特的平均回收率为94.3%~103.1%;方法的日内和日间的相对标准偏差(RSD)均小于6%;最低检测限(LOD)与定量限(LOQ)分别为9.0和30 μg/L;为临床上人体血清中苯扎贝特的浓度检测提供了一种重现性好、灵敏度高的分析方法。     

控制脑电波

George Manson大学在新开展的一项研究工作中证实了可以用电场改变在大脑组织中传播的脑电波的预言．这可能是用电场来改变神经元的阈值从而控制脑电波的运动的第一个例子实际上，这也是首次通过改变阈值来控制可激发介质中的波．研究人员对一老鼠大脑皮层的切片进行了研究；这片大脑组织包括6层2维的神经元薄层．