一种pH敏感相分离高分子在免疫分析中的应用

将乙肝表面抗体与N-羟基琥珀酰亚胺丙烯酸酯反应，生成丙烯酰基抗体．丙烯酰基抗体与甲基丙烯酸、丙烯酰胺共聚，生成pH敏感的三元共聚物．三元共聚物溶解．沉淀的临界pH值为3．8．三元共聚物上的抗体能与表面抗原、酶标抗体形成夹心复合物．利用三元共聚物可逆的溶解．沉淀特性，能实现在均相条件下，进行免疫反应，在异相条件下，进行免疫复合物的分离．     

An Unusual Reductive Ring-opening Reaction of Phthalimide with Sodium Hydride in DMF

An unusual reductive ring-opening reaction of phthalimide with sodium hydride in anhydrous DMF was observed for the first time. The presumed mechanism was described in detail.     

2-碘-N-甲基苯磺酰胺的合成新方法和分子结构

选用新方法合成了2-碘—N-甲基苯磺酰胺，通过^1H NMR,^13C NMR,^13C DEPT NMR(Distortionless Enhancement by Polarization Transfer NMR)和MS确证的其结构。     

Monitoring the Aggregation of Dansyl Chloride in Acetone through Fluorescence Measurements

The aggregation of dansyl chloride (DNS-Cl) in acetone has been studied in detail by steady-state fluorescence techniques.It has been demonstrated that DNS-Cl is stable in acetone during purification and aggregation study processes.The aggregates are not solvolyzed in acetone,and do not take part n any chemical reactions either.It has been found that DNS-Cl tends to aggregate even when its concentration is much lower than its solubility in acetone.The aggregation is reversible,and both the aggregation and the deaggregation are very slow processes.Introduction of SDS has a positive effect upon the formation and stabilization of the aggregates.     

枸橼酸莫沙必利的合成

分别以邻羟基对氨基苯甲醇钠，对氟苯甲醛，邻苯二甲酰亚胺为起始原料，制得3个中间体，用其中2个中间体经偶合，环化后与第3个中间体反应，再经成盐制得产品，其摩尔总收率为31．5％。     

苯磺酰苯胺类药物理化性能的研究

利用高效液相色谱和分光光度法，研究了新合成的5个苯磺酰苯胺类化合物的酸离解常数和脂溶性，结果表明，他们具有较弱的酸性和合适的脂溶性。预计会有较好的抗肝片吸虫活性。     

改性强酸性阳离子交换树脂的合成及性能研究

对聚苯乙烯－二乙烯基苯磺酸型阳离子交换树脂（Ｄ７２树脂）分别通过氯代和深度磺化进行改性。研究了改性前后的各种树脂的磺酸基团在苯酚介质中的降解动力学和树脂催化活性及选择性。结果表明，两种改性树脂的热稳定性均较Ｄ７２树脂有所降低，而氯代树脂的催化活性及选择性均比Ｄ７２树脂有明显的提高。     

聚苯乙烯磺酰氯和聚苯乙烯亚磺酸盐的合成及其应用

本文以36篇文献，包括作者近年的工作，综述了聚苯乙烯磺酰氯和聚苯乙烯亚磺酸盐的合成方法和这些功能基化聚合物在有机合成及其他方面的应用。