Studies on metabolism of total glucosides of paeony from Paeoniae Radix Alba in rats by UPLC‐Q‐TOF‐MS/MS

Total glucosides of paeony are the active constituents of Paeoniae Radix Alba. In this study, a novel strategy was proposed to find more metabolites and the differences between paeoniflorin, albiflorin and total glucosides of paeony (TGP). This strategy was characterized as follows: firstly, the animals were divided into three groups (paeoniflorin, albiflorin and TGP) to identify the source of TGP metabolites from paeoniflorin or albiflorin; secondly, a generic information‐dependent acquisition scan for the low‐level metabolites was triggered by the multiple mass defect filter and dynamic background subtraction; thirdly, the metabolites were identified with a combination of data‐processing methods including mass defect filtering, neutral loss filtering and product ion filtering; finally, a comparative study was used in the metabolism of paeoniflorin, albiflorin and TGP. Based on the strategy, 18 metabolites of TGP, 10 metabolites of paeoniflorin and 13 metabolites of albiflorin were identified respectively. The results indicated that the hydrolysis, conjugation reaction and oxidization were the major metabolic pathways, and the metabolic sites were the glycosidic linkage, the ester bond and the benzene ring. This study is first to explore the metabolism of TGP, and these findings enhance our understanding of the metabolism and the interactions of paeoniflrin and albiflorin in TGP. Copyright © 2015 John Wiley & Sons, Ltd.     

A model study for the steady state error of numerical approximations of inviscid flow equations on Cartesian grid

The widely used locally adaptive Cartesian grid methods involve a series of abruptly refined interfaces. In this paper we consider the influence of the refined interfaces on the steady state errors for second‐order three‐point difference approximations of flow equations. Since the various characteristic components of the Euler equations should behave similarly on such grids with regard to refinement‐induced errors, it is sufficient enough to conduct the analysis on a scalar model problem. The error we consider is a global error, different to local truncation error, and reflects the interaction between multiple interfaces. The steady state error will be compared to the errors on smooth refinement grids and on uniform grids. The conclusion seems to support the numerical findings of Yamaleev and Carpenter (J. Comput. Phys. 2002; 181: 280–316) that refinement does not necessarily reduce the numerical error. Copyright © 2005 John Wiley & Sons, Ltd.     

知识发现中一种变化趋势模型的算法研究

在时序数据库中,有许多成熟的技术和方法用来对布尔型属性之间的关系进行挖掘,但对于数值型属性变化趋势关联关系的研究却不是很多.本文提出了一种数值型属性变化趋势的研究模型QMP(QuantityMovementPattern),依据该模型可利用数据挖掘算法发现不同数值型属性之间变化趋势之间的关系.文中分析了该模型的几种实现算法,并给出了一种快速实现算法及实验数据.     

The Frontier Movement and The American Values and Beliefs

This paper briefly accounts the background of American values and beliefs. It analyses the essence of the American ideals and points out that the American values are exaggerated and glamorized by the American upper class. They are in a sense, a dose of anaesthetic and a kind of hypocrisy.     

任意实矩阵的优势特征值

对任意实矩阵本文证明了利用位移技术，在不涉及复运算的前提下，可以求得一个或一对优势特征值。并探讨上述结果的数值实现途径．     

Authorware7.0在《模拟电子技术》多媒体教学课件中的应用

文章介绍了Authorware7．0多媒体开发软件的功能特点及主要技术，并通过部分程序设计阐述了其在《模拟电子技术》多媒体教学课件中的应用，最后总结了用Authorware7.0开发课件的优点．     

1998年至2003年山西省科技进步统计分析

通过山西省5年期间科技进步统计检测指标位次，进一步分析了科技进步统计监测体系的四个一级指标。     

反应条件及添加惰性物质对三聚甲醛合成反应的影响

研究了三聚甲醛合成过程进料浓度、催化剂用量等对副产物（特别是甲酸）生成行为的影响。结果表明，该体系副产物的生成强烈地依赖于反应时间和催化剂硫酸的用量，而与原料浓度的波动无关。在反应－精馏过程的反应器中添加惰性高沸有机物，可有效地缩短反应物的停留时间，提高三聚甲酸的选择性，大大降低快速反应－精馏过程对反应器的设计要求。