急性和慢性缺氧对人体脑电图的影响

本文报道 36名受试者吸入低氧混合气(7000 m)或低压舱急性减压低氧(5000—7500 m)条件下和 46名受试者到达高海拔地区(5000—8600 m)慢性缺氧条件下的脑电图,并对这两组受试者在安静状态、光刺激、过度通气时和中断缺氧后恢复过程中的脑电图特征进行了比较.实验结果表明,在同一个体,缺氧程度愈重,脑电图的变化愈著;在同一高度,急性缺氧比慢性缺氧引起的脑电图变化明显,但恢复速度比慢性缺氧为快。在慢性缺氧条件下,过度通气引起的脑电图变化比急性缺氧条件下为轻;光刺激可使急、慢性缺氧条件下以慢波为特征的脑电图上出现暂时的α波.本文还分析了急、慢性缺氧条件下脑电图变化的可能机制。     

EXPERIMENTAL STUDY OF INTRACRANIAL HYPERTENSION

The present investigation was made in rabbits and cats with perfusing mock corebrospinal fluid into fourth ventrieulus to produce experi mental diffusion intracranial hypertension. Under normoxia and acute hypoxia conditions, the changes in cerebral blood flow, spontaneous electrocortical activity, direct cortical response, electrocardiogram, blood pressure and cerebral perfusion pressure were measured as intracranial hypertension caused by step elevation and abrupt elevation; at the same time, the relationship mentioned above was also investigated. The experimental results are very important to clinic treatment and to the patients suffering from anoxia with intracranial hypertension.     

小麦taf1位点的连锁不平衡分析

利用遍布全基因组的21个SSR分子标记,对小麦雌性不育系XND126与1201、802、60个普通小麦品种(系)组成的三个品种(系)群体进行群体结构的评估,发现在三个群体中都存在群体结构.对消除群体结构后的三个亚群体中各标记的连锁不平衡值(linkage disequilibrium value)进行比较.结果表明,群体大小影响标记与雌性育性位点间的LD值.基于对小麦雌性育性taf1位点初步定位的信息.对2DS染色体上30个SSR分子标记的LD研究显示,Xgwm71、Xwmc25、Xgwm515、Xcfd36同样与原标记Xgdm35等具有较大的LD值,可能与taf1密切相关.获得这些较大LD值的标记(Xgwm71、Xwmc25等),为taf1位点的精细定位做出了充分的准备.     

THE INFLUENCE OF ACUTE AND CHRONIC HYPOXIA ON THE ELECTROENCEPHALOGRAM OF HUMAN BODY

This report deals with the study of electroencephalograms of 36 subjects who inhaled hypoxic mixture at the sea level (Po_2 is as that at 7000 m above sea level) or in a hypobaric chamber with rapid decompression (as that at 5000—7500 m above sea level) and of 46 subjects who reached high altitude area (5000—8600m) under chronic hypoxia. The characters of the EEGs at rest during photie stimulation, hyperventilation and convalescence after hypoxia were compared in two experiments. The result of experiments shows that in the same individual, the severer the hypoxia, the more obvious the changes on the EEGs. At the same altitude, acute hypoxia causes more obvious changes on the EEGs than chronic one does, but its speed of recovery is faster than that of chronic hypoxia. Under chronic hypoxia, the changes on the EEGs caused by hyperventilation are slighter than those under acute hypoxia. When photic stimulation is given, there is temporary appearance of a waves on the EEGs featuring slow waves under acute     

实验性颅内高压研究

本文是在实验动物(兔和猫)上用第四脑室灌注人工脑脊液的方法造成实验性弥漫性颅内高压。研究在常氧和急性低氧条件下阶梯性和急骤性方式升高颅内压力时脑血流、脑自发电活动、直接皮层反应、心电图、血压和灌注压的变化,同时还研究其相互关系。本研究结果对临床,尤其对缺氧性颅内高压病人具有重要的参考价值。     

小麦染色体2DS雌性育性位点遗传多态性分析

小麦雌性不育系XND126属于生态遗传型不育系.通过SSR分子标记分析,在2DS染色体上定位了一个雌性育性主效QTL位点.为了构建高密度遗传图谱并精细定位该主效位点,用2DS参考遗传图谱上的14对SSR标记,研究了59个育性正常的普通小麦品种与XND126的DNA多态性,筛选到不同生态型多态性较高的品种共12个,每个品种多态性标记达12~13个,这些品种可以用作杂交亲本,构建新的QTL精细定位群体.在品种组成的群体中,与主效基因位点最近的标记,表现出有较多的品种与雌性不育系具有差异.