Effect of helium-neon laser on fast excitatory postsynaptic potential of neurons in the isolated rat superior cervical ganglia

The aim of this study is to further measure the effect of 632.8-nm helium-neon laser on fast excitatory postsynaptic potential (f-EPSP) of postganglionic neurons in isolated rat superior cervical ganglia by means of intracellular recording techniques. The neurons with f-EPSP were irradiated by different power densities (1 - 5 mW/cm2) laser. Irradiated by the 2-mW/cm2 laser, the amplitude of the f-EPSP could augment (P < 0.05, paired t test) and even cause action potential at the end of the first 1 - 2 minutes, the f-EPSP could descend and last for 3 8 minutes. But the amplitude of the f-EPSP of neurons irradiated by the 5-mW/cm2 laser could depress for the irradiating periods. The results show that: 1) the variation of the amplitude of f-EPSP caused by laser is power density-dependent and time-dependent; 2) there exist the second-order phases in the interaction of the helium-neon laser with neurons. These findings may provide certain evidence in explanation of the mechanisms of clinical helium-neon lase     

Depolarization Induced by Substance P on Rat Stellate Ganglion Neurons

应用细胞内生物电记录技术，观察神经肽Ｐ物质（ＳＰ）对大鼠星状神经节细胞的影响。ＳＰ在１μｍｏｌ～１０μｍｏｌ或更高的浓度范围内，供试３５个细胞，有２８个细胞发生膜除极反应。用低钙（０．２５ｍｍ）或用含河豚毒素（ＴＴＸ，１μｍｏｌ）克氏液灌流神经节，不影响ＳＰ引起的除极反应的幅度和时程。ＳＰ引起除极反应的同时常伴有膜电阻增大。当膜电位增大时，除极化反应幅度变小，反转电位为－８０ｍＶ至－１００ｍＶ。研究表明，ＳＰ对部分星状神经节细胞具有兴奋作用，使通过这些细胞的信息传递增强；ＳＰ对细胞膜的除极作用是由于其引起细胞膜钾导降低所致。     

基于Weibull函数和价格折扣的易腐品库存订货与定价策略

【目的】研究需求率为售价的指数函数，变质率服从三参数Weibull分布的订货与定价策略。【方法】系统以利润最大化为目标函数，考虑商品变质时带来的成本，引入价格折扣，构建了库存模型。【结果】采用直接法和泰勒展开式对模型进行近似求解，提供算例分析以得到问题的近似解，通过对折扣率、变质率灵敏度分析给出了相应的合理化管理建议。【结论】零售商在处理保鲜期后的商品时引入的价格折扣越高销量越大。商品的流动环境因子的增加会使得零售商成本增加，在销售过程中可采用更为先进的交通工具和储存手段。     

刚架拱桥的病害原因与加固分析

通过对多座刚架拱桥的病害调查,全面分析刚架拱桥的常见病害并对其原因进行针对性分析.本文结合钦州钦江二桥的检测,对钦江二桥出现的病害加以分析,在此基础上提出加固方案,并为同种类型的刚架拱桥的加固提供依据.     

P物质对大鼠星状神经节细胞的影响

应用细胞内生物电记录方法，观察神经肽Ｐ物质（ＳＰ）对大鼠星状神经节能细胞的影响，用灌流或用加压向细胞周围施加ＳＰ可使部分细胞发生膜除极反应，用低钙或用含河豚毒素克氏液灌流神经节，并不影响ＳＰ引起的除极反应的幅度和时程。ＳＰ引起除极反应的同时常伴有膜电阻增大，当膜电位增大时，除极化反应幅度变小，反转电位为－８０ｍＶ至－１００ｍＶ，研究表明，ＳＰ对部分星状神经节细胞具有直接兴奋作用，并且ＳＰ对细胞膜的     

上海车展营销凸现三大铁律

这场令人陶醉的汽车“嘉年华会”终于落下了帷幕,每个人都在热衷于讨论它能留下些什么?靓车、美女、金钱、奢华、似乎都是主旋律,似乎又都不是关键字。有人辞官归故里,有人漏夜赶考场;态度各异的汽车厂商们,在以各自的方式和复杂的心态看待一年复一年的上海车展。上海车展,风一般刮过,给我们昭示的是中国车展市场三大独特的定律。     

P物质对大鼠星状神经节细胞的除极化

应用细胞内生物电记录技术,观察神经肽P物质(SP)对大鼠星状神经节细胞的影响.SP在1 μmol～10 μmol或更高的浓度范围内,供试35个细胞, 有28个细胞发生膜除极反应.用低钙(0.25 mm)或用含河豚毒素(TTX,1 μmol)克氏液灌流神经节,不影响SP引起的除极反应的幅度和时程.SP引起除极反应的同时常伴有膜电阻增大.当膜电位增大时,除极化反应幅度变小,反转电位为-80 mV至-100 mV.研究表明,SP对部分星状神经节细胞具有兴奋作用,使通过这些细胞的信息传递增强;SP对细胞膜的除极作用是由于其引起细胞膜钾导降低所致.     

大气边界层(摘译)

大气边界层的定义:在大尺度空气流中,由于湍流摩擦和科里奥利力共同作用的结果,在行星表面附近形成了大气边界层。大气边界层与一般工程中所考虑的大多数边界层不同。它的特点是受科里奥利力(亦即行星旋转)的影响。也受空气密度分层的影响(通过浮力影响湍流),因而大气边界层是旋转分层重流体中的湍流边界层。      

Effect of helium-neon laser on fast excitatory postsynaptic potential of neurons in the isolated rat superior cervical ganglia

The aim of this study is to further measure the effect of 632.8-nm helium-neon laser on fast excitatory postsynaptic potential(f-EPSP)of postganglionic neurons in isolated rat superior cervical ganglia by means of intracellular recording techniques.The neurons with f-EPSP were irradiated by different power densities(1 - 5 mW/cm2)laser.Irradiated by the 2-mW/cm2 laser,the amplitude of the f-EPSP could augment(P ＜ 0.05,paired t test)and even cause action potential at the end of the first 1 - 2 minutes,the f-EPSP could descend and last for 3 - 8 minutes.But the amplitude of the f-EPSP of neurons irradiated by the 5-mW/cm2 laser could depress for the irradiating periods.The results show that:1)the variation of the amplitude of f-EPSP caused by laser is power density-dependent and time-dependent; 2)there exist the second-order phases in the interaction of the helium-neon laser with neurons.These findings may provide certain evidence in explanation of the mechanisms of clinical helium-neon laser therapy.     

有机锗药理、毒理及应用研究进展

有机锗是近３０年研究较多的化合物。有机锗的药理作用主要有抗癌、抗炎、抗病毒和免疫调节、抗衰老等;毒理学研究显示有机锗有长期毒性;通过细胞和分子水平研究来阐明有机锗确切作用机理,才能使有机锗更好地为人类键康服务。