Comprehensive Profiling by Non-targeted Stable Isotope Tracing Capillary Electrophoresis-Mass Spectrometry: A New Tool Complementing Metabolomic Analyses of Polar Metabolites

Mass spectrometry (MS) driven metabolomics is a frequently used tool in various areas of life sciences; however, the analysis of polar metabolites is less commonly included. In general, metabolomic analyses lead to the detection of the total amount of all covered metabolites. This is currently a major limitation with respect to metabolites showing high turnover rates, but no changes in their concentration. Such metabolites and pathways could be crucial metabolic nodes (e.g., potential drug targets in cancer metabolism). A stable-isotope tracing capillary electrophoresis–mass spectrometry (CE-MS) metabolomic approach was developed to cover both polar metabolites and isotopologues in a non-targeted way. An in-house developed software enables high throughput processing of complex multidimensional data. The practicability is demonstrated analyzing [U-¹³C]-glucose exposed prostate cancer and non-cancer cells. This CE-MS-driven analytical strategy complements polar metabolite profiles through isotopologue labeling patterns, thereby improving not only the metabolomic coverage, but also the understanding of metabolism.     

Zeeman效应实验一定能推断出原子的g_J值吗?

本文以实例对Zeeman效应一定能推断原子的gJ值问题做了否定的回答。     

SEPARATING SCN~- FROM DESULPHURIZATION WASTE SOLUTION OF COCKING PLANT BY D241 RESIN

1. INTRODUCTION In the process of coking plant, about 30%~35% sulfur is transformed to H2S and some other sulfide, which form impurity in coal gas together with NH3 and HCN. Only 0.1% H2S containing in air can lead to die, so it is very important to carry on desulphurization and decyanation with coal gas [1~3]. Currently desulphurization and decyanation craft technique have Dry Oxidation Technology, Wet Oxidation Technology and Liquid Absorption Technology [2] three main kinds. The…     

Ionic conductivity of multiarm star polymer/LiClO4 electrolytes

A series of polymer electrolytes based on multiarm polymers and lithium salt complexes were characterized by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), and impedance measurement. The relationships of conductivity with salt concentration, temperature, and arm numbers are discussed. It is suggested that the star polymer has a higher solvency and ion transfer ability on lithium salts than on linear polymers. The conductivity maximum appeared at a higher salt concentration ([EO]/[Li] = 4). Impedance measurement suggested that the optimum conductivity was 2 × 10^?4 s · cm^?1. The conductivity increased with temperature and the dependence of ionic conductivity on temperature fits the Arrhenius equation. Among the studied systems, the star polymer with a five arm number performs better than other structures. © 2004 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 42: 4195–4198, 2004     

p+209Bi核反应微观数据的理论计算

利用光学模型、激光模型、蒸发模型及扭曲波玻恩近似理论,对入射能量从阈能到300MeV,p+²⁰⁹Bi的中子反应截面、剩余核截面、出射粒子的多重数进行了理论计算及分析,并将计算结果与实验数据进行了比较.同时得到一组能量到50?0MeV与实验数据符合很好的光学势参数.     

达县广电城域网运行状况及故障分析

对达县广电城域网运行状况进行了检测，认为不能满足用户上网需要的原因除了网内病毒感染之外，设备与设备之间链路层协商及连接线出现故障。改进措施主要有两点：解决NE08E与S8505的连接问题，解决S8505上的DHCP服务器不能分配IP地址问题。     

基于通信信道的视频传输系统的设计

提出了一种利用PCM基群信道进行视频信号传输的方法,介绍了传输系统的工作原理,对视频编码器进行了较为详细的分析,并采用数字信号处理器作控制器,实现了视频信号的实时传输。     

STUDY ON PHASE PERCEPTION IN SPEECH

The perceptual effect of the phase information in speech has been studied by auditory subjective tests. On the condition that the phase spectrum in speech is changed while amplitude spectrum is unchanged, the tests show that: (1) If the envelop of the reconstructed speech signal is unchanged, there is indistinctive auditory perception between the original speech and the reconstructed speech; (2) The auditory perception effect of the reconstructed speech mainly lies on the amplitude of the derivative of the additive phase; (3) td is the maximum relative time shift between different frequency components of the reconstructed speech signal. The speech quality is excellent while td <10ms; good while 10ms< td <20ms; common while 20ms< td <35ms, and poor while td >35ms.     

Datacryptor~64E剖析

Datacryptor 64E是数据包端一端保密机,用于保护经公用和专用X.25包交换网传输的敏感而有价值的信息。在传输之前先将数据加密,加密后的数据经网络传输,在其终点予以解密。 Datacryptor 64E仅对包的数据字段加密,地址和控制信息仍为明文,以保证数据包正确地通过网的路由传输。既然本设备用于端一端加密,这就意味着它仅安装在网络的终点处,而不是安装在每个网络的链路上。     

用于留数算术中的数值／留数／数值的转换

介绍用光学方法完成留数算术中的数值/留数/数值的转换,并附有实验结果。