全文获取类型
收费全文 | 267篇 |
免费 | 4篇 |
国内免费 | 1篇 |
专业分类
化学 | 151篇 |
晶体学 | 2篇 |
力学 | 3篇 |
数学 | 21篇 |
物理学 | 95篇 |
出版年
2023年 | 3篇 |
2022年 | 3篇 |
2021年 | 5篇 |
2020年 | 3篇 |
2019年 | 7篇 |
2018年 | 13篇 |
2017年 | 12篇 |
2016年 | 14篇 |
2015年 | 11篇 |
2014年 | 10篇 |
2013年 | 13篇 |
2012年 | 22篇 |
2011年 | 22篇 |
2010年 | 9篇 |
2009年 | 12篇 |
2008年 | 19篇 |
2007年 | 15篇 |
2006年 | 13篇 |
2005年 | 7篇 |
2004年 | 7篇 |
2003年 | 8篇 |
2002年 | 8篇 |
2001年 | 4篇 |
2000年 | 5篇 |
1999年 | 1篇 |
1997年 | 1篇 |
1996年 | 3篇 |
1991年 | 1篇 |
1990年 | 1篇 |
1989年 | 2篇 |
1985年 | 1篇 |
1984年 | 2篇 |
1982年 | 3篇 |
1981年 | 3篇 |
1980年 | 2篇 |
1977年 | 2篇 |
1974年 | 1篇 |
1973年 | 1篇 |
1972年 | 1篇 |
1969年 | 1篇 |
1967年 | 1篇 |
排序方式: 共有272条查询结果,搜索用时 15 毫秒
1.
Abstract In the presence of the photosensitizer riboflavin at high fluence rates a photoproduct, most probably H2 O2 , is formed which causes negative phototaxis in the colorless flagellate Polytomella magna . The aim of this study was to find out whether H2 O2 is produced in a type I or II reaction. As has been shown, 1 O2 quenchers either do not influence the photodynamic action of riboflavin (furfuryl ethanol, DPBF, l -histidine, crocetin) or show slight quenching effects only at very high concentrations ≧ 10−2 M (DABCO, DMF, imidazole). D2 O is toxic to P. magna even in 1:1 and 1:2 mixtures with H2 O. On the other hand, the quenching effect of 1,4-benzoquinone, highly indicative for the type I pathway, is more than two orders of magnitude stronger than the one of the above mentioned 1 O2 quenchers. The results suggest that H2 O2 is produced in a type I reaction. Superoxide does not seem to be involved since superoxide dismutase does not diminish the photodynamic effect of riboflavin. 相似文献
2.
Yagi H Ramesha AR Kalena G Sayer JM Kumar S Jerina DM 《The Journal of organic chemistry》2002,67(19):6678-6689
We describe a novel and efficient synthesis (62-84% yields) of the eight possible, diastereomerically pure, cis and trans, R and S O(6)-allyl-protected N(2)-dGuo phosphoramidite building blocks derived through cis and trans opening of (+/-)-3alpha,4beta-dihydroxy-1beta,2beta-epoxy-1,2,3,4-tetrahydrobenzo[c]phenanthrene [BcPh DE-1 (1)] and (+/-)-3alpha,4beta-dihydroxy-1alpha,2alpha-epoxy-1,2,3,4-tetrahydrobenzo[c]phenanthrene [BcPh DE-2 (2)] by hexafluoropropan-2-ol (HFP)-mediated addition of O(6)-allyl-3',5'-di-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine (3) at C-1 of the epoxides. Simply changing the relative amount of HFP used in the reaction mixture can achieve a wide ratio of cis/trans addition products. Thus, the observed cis/trans adduct ratio for the reaction of DE-1 (1) in the presence of 5 equiv of 3 varied from 17/83 to 91/9 over the range of 5-532 equiv of HFP. The corresponding ratios for DE-2 (2) varied from 2/98 to 61/39 under the same set of conditions. When 1 or 2 was fused with a 20-fold excess of 3 at 140 degrees C in the absence of solvent HFP, almost exclusive trans addition (>95%) was observed for the both DEs. Through the use of varying amounts of HFP in the reaction mixture as described above, each of the eight possible phosphoramidite oligonucleotide building blocks (DE-1/DE-2, cis/trans, R/S) of the BcPh DE N(2)-dGuo adducts can be prepared in an efficient fashion. To rationalize the varying cis-to-trans ratio, we propose that the addition of 3 to 1 or 2 in the absence of solvent or in the presence of small amounts of HFP proceeds primarily via an S(N)2 mechanism to produce mainly trans-opened adducts. In contrast, increasing amounts of HFP promote increased participation of an S(N)1 mechanism involving a relatively stable carbocation with two possible conformations. One of these conformations reacts with 3 to give mostly trans adduct, while the other conformation reacts with 3 to give mostly cis adduct. 相似文献
3.
4.
Our earlier model of re-entrant liquid crystalline phases exhibited by highly polar compounds, in which the mutual orientation of near-neighbour molecules can change from an antiparallel to a parallel configuration, has been extended to include both nematic and smectic interactions. We show that, as the McMillan parameter alpha is decreased, the SmAd-SmA1 line goes over to the SmAd-N1Re line, finally becoming the NdRe-N1Re transition line, the latter ending in a critical point. This sequence is in agreement with the predictions of Prost's Landau model as well as with an experimental result. The phase sequence N-SmAd-NdRe-N1Re-SmA1 is obtained on cooling for a range of alphaA values. 相似文献
5.
Poojali P. Warekar Priyanka T. Patil Kirti T. Patil Dattatraya K. Jamale Govind B. Kolekar 《合成通讯》2016,46(24):2022-2030
An ecofriendly route has been investigated for the synthesis of 4-(4-nitro-phenyl)-2-phenyl-1,4-dihydro-benzo[4,5]imidazo[1,2-a]pyrimidine-3-carboxylic acid ethyl ester derivatives by one-pot, three-component condensation of ethyl benzoylacetate, aromatic aldehydes, and 2-amino benzimidazole using 260?mol% of citric acid as reaction mediator. Citric acid is an inexpensive, nontoxic, and green medium with smoothly activates the rate of reaction. The synthesized compounds were assessed for in vitro antimycobacterial activity against Mycobacterium tuberculosis H37RV strain using the microplate alamar blue assay (MABA). The results indicate that among all the synthesized compound series, P-4 and P-9 compounds illustrate effective activity with a minimum inhibitory concentration of 25?µg/ml. 相似文献
6.
Hiromu Kurosaki April A. Tucker Sarah E. Iden Shirley M. Sexton Benito D. Gonzalez Govind R. Rao 《Journal of Radioanalytical and Nuclear Chemistry》2013,298(2):1017-1022
Routine monitoring of urine is an effective way to detect occupational intake of radioactive material. Historically, determinations of uranium isotopic ratios have been performed by radiochemical separation followed by alpha spectrometry. With recent advancements in technology, inductively coupled plasma-mass spectrometry (ICP-MS) has become widely available for the determination of trace metals as well as radioactive nuclides with long half-lives, such as 238U in urine. Furthermore, ICP-MS measurements of 238U do not require radiochemical separation since the number of atoms in the sample is determined instead of the number of alpha particles emitted. However, this method does not provide good sensitivity for the determination of 235U due to its shorter half-life. An improved procedure using pre-concentration of uranium and determination by ICP-MS decreases the detection limit by a factor of ten or greater with only slight increase in total analysis time. The method also has the capability of accurately determining the isotopic ratio of the sample, which is very important in cases where enriched or depleted uranium is involved. 相似文献
7.
EPR measurements of Cr3+ doped diammonium hexaaqua magnesium sulphate single crystals are made at room temperature. The crystal field and spin Hamiltonian parameters are evaluated from the resonance lines obtained at different angular orientations. The value of g=1.9763±0.0002 and are evaluated. On the basis of EPR data the site symmetry of Cr3+ in the crystal is discussed. Optical absorption studies of single crystals are also carried out at room temperature. The orbital energies of the chromium ion are estimated from the optical absorption spectrum. The different bonding parameters are obtained by correlating optical and EPR data and the nature of bonding in the crystal is discussed. The values of Racah parameters (B and C), crystal field parameter (Dq) and nephelauxetic parameters (h and k) are obtained as B=676,C=3371, , h=1.258 and k=0.21. 相似文献
8.
Awalekar Ramchandra Mohire Priyanka Patravale Ajinkya Salunkhe Shilpa Usmani Shams Jamale Dattatray Hangirgekar Shankar Kolekar Govind Anbhule Prashant 《Chemistry of Natural Compounds》2021,57(6):1000-1004
Chemistry of Natural Compounds - (3E,7Z)-Tetradecadienyl acetate, the major sex pheromone component of the potato pest Symmetrischema tangolias (Gyen), was stereoselectively synthesized from the... 相似文献
9.
Har Mohindra Chawla Satya Narayan Sahu Rahul Shrivastava Satish Kumar 《Tetrahedron letters》2012,53(17):2244-2247
A series of calix[4]arene based ditopic receptors possessing bipyridyl and hydrazone units have been synthesized and evaluated for ionic recognition. It has been observed that the synthesized derivatives function as allosteric receptors for simultaneous recognition of Co2+and F? ions through non-covalent interactions. Significant bathochromic shifts in the UV–visible spectrum with a profound colour change promise their use to engineer novel applications. 相似文献
10.
Kurosaki Hiromu Mueller Rebecca J. Lambert Susan B. Rao Govind R. 《Journal of Radioanalytical and Nuclear Chemistry》2017,311(1):323-329
Journal of Radioanalytical and Nuclear Chemistry - An alternate method of preparing actinide alpha counting sources was developed in place of electrodeposition or lanthanide fluoride... 相似文献