排序方式: 共有5条查询结果,搜索用时 218 毫秒
1
1.
2.
Preparation of dextran immunological magnetic nanoparticles and their application to combined targeting carrier 总被引:1,自引:0,他引:1
Superparamagnetic dextran nanoparticles were prepared by coprecipitation. Effects of concentration of dextran, amount of ironic salts, stirring speed, concentration of ammonium hydroxide and mole ratio of Fe3+/Fe2+ on the effective diameter of dextran magnetic nanopartides (DMNP) were studied. Dextran immunological magnetic nanoparticles (DIMNP) were formed by the reaction of the monoclonal anti-human mammary cancer antibody with DMNP oxidized by sodium periodate, and the properties of magnetic susceptibility, shape and retention of antibody activity were investigated. The in vitro cancer antigen binding ability of DIMNP was demonstrated by radioimmunoassay, and the in vivo magnetic localization and antibody targeting ability of radiolabeled DIMNP were studied. 相似文献
3.
葡聚糖免疫磁性毫微粒的制备及作为复合靶向载体研究 总被引:14,自引:0,他引:14
用共沉淀法制备出具有超顺磁性的葡聚糖磁性毫微粒.研究了制备过程中葡聚糖浓度、铁盐用量、搅拌速度、氨水浓度和Fe~(3+)/Fe~(2+)摩尔比对葡聚糖磁性毫微粒有效粒径的影响.抗人乳腺癌单抗与高碘酸钠氧化的葡聚糖磁性毫微粒反应形成葡聚糖免疫磁性毫微粒,并对它的磁化率、形态和抗体保留活性等性质进行了研究.通过放射免疫实验考察葡聚糖免疫磁性毫微粒体外结合肿瘤抗原的能力,同时研究了放射性标记的葡聚糖免疫磁性毫微粒在动物体内的磁性和抗体导向能力. 相似文献
4.
采用二维核磁共振波谱完全归属了天然有机化合物香茶菜醛的~1H和~(13)C NMR化学位移,测定了部分质子的偶合常数,并用孤立自旋对近似方法定量处理香茶菜醛的相敏NOESY谱,根据1/r_(ij)~8∝A_(ij)计算出相应的质子间距离.其溶液中的三维空间结构采用以NMR结构参数为初始数据的WUPH计算程序和分子力学能量优化(MM2)完成计算.计算结果表明,得到的香茶菜醛在溶液中的三维空间结构反映了该化合物在溶液中的真实空间结构. 相似文献
5.
1