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Zarafu Irina Badea Mihaela Ioniţă Gabriela Chifiriuc Mariana Carmen Bleotu Coralia Popa Marcela Ioniţă Petre Tatibouët Arnaud Olar Rodica 《Journal of Thermal Analysis and Calorimetry》2019,136(5):1977-1987
Journal of Thermal Analysis and Calorimetry - A series of complexes [Cu(L)(CH3COO)2]·nH2O (L: isonicotinic acid 2-(2-hydroxy-8-substituted-tricyclo[7.3.1.02.7]tridec-13-ylidene)-hydrazones)... 相似文献
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Zarafu Irina Olar Rodica Chifiriuc Mariana Carmen Bleotu Coralia Ioniţă Petre Mulţescu Mihaela Ioniţă Gabriela Grădişteanu Graţiela Tatibouët Arnaud Badea Mihaela 《Journal of Thermal Analysis and Calorimetry》2018,134(3):1851-1861
Journal of Thermal Analysis and Calorimetry - A series of Schiff bases resulted in the [1?+?1] condensation of 8-alkyl-2-hydroxy-tricyclo[7.3.1.02.7]-tridecan-13-one with the... 相似文献
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Ilinca Margareta Vlad Diana Camelia Nu Robert Viorel Ancuceanu Miron Teodor Caproiou Florea Dumitrascu Ioana Cristina Marinas Mariana Carmen Chifiriuc Luminita Gabriela Mruescu Irina Zarafu Ioana Raluca Papacocea Bogdan tefan Vasile Adrian Ionu Nicoar Cornelia-Ioana Ilie Anton Ficai Carmen Limban 《Molecules (Basel, Switzerland)》2021,26(10)
Antimicrobial resistance is one of the major public health threats at the global level, urging the search for new antimicrobial molecules. The fluorene nucleus is a component of different bioactive compounds, exhibiting diverse pharmacological actions. The present work describes the synthesis, chemical structure elucidation, and bioactivity of new O-aryl-carbamoyl-oxymino-fluorene derivatives and the contribution of iron oxide nanoparticles to enhance the desired biological activity. The antimicrobial activity assessed against three bacterial and fungal strains, in suspension and biofilm growth state, using a quantitative assay, revealed that the nature of substituents on the aryl moiety are determinant for both the spectrum and intensity of the inhibitory effect. The electron-withdrawing inductive effect of chlorine atoms enhanced the activity against planktonic and adhered Staphylococcus aureus, while the +I effect of the methyl group enhanced the anti-fungal activity against Candida albicans strain. The magnetite nanoparticles have substantially improved the antimicrobial activity of the new compounds against planktonic microorganisms. The obtained compounds, as well as the magnetic core@shell nanostructures loaded with these compounds have a promising potential for the development of novel antimicrobial strategies. 相似文献
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Anca Paun Irina Zarafu Miron T. Caproiu Constantin Draghici Maria Maganu Ani I. Cotar Mariana C. Chifiriuc Petre Ionita 《Comptes Rendus Chimie》2013,16(7):665-671
Starting from benzocaine, a well-known anaesthetic, ten derivatives were synthesized and characterized by UV–vis, IR, NMR, and elemental analysis. Most of the compounds contain residues with recognized biological activity, like nicotinic acid (vitamin B3 or PP), biotin (vitamin B7 or H), lipoic acid (thioctic acid), adamantine, as well as other residues of crown-ether type, benzofurazane, naphtylurea, di- and tri-nitrobenzene, and a nitroxide radical. The biological evaluation of the obtained compounds included hydrophobicity (lipophobicity) assay, total antioxidant and microbiological activity tests. 相似文献
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