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JETP Letters - Extraordinary multiparticle effects in quantizing magnetic fields that are manifested in strongly interacting two-dimensional electron systems in MgZnO/ZnO heterostructures have been... 相似文献
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Solvent Influence on Cellulose 1,4‐β‐Glycosidic Bond Cleavage: A Molecular Dynamics and Metadynamics Study 下载免费PDF全文
Claudia Loerbroks Eliot Boulanger Prof. Dr. Walter Thiel 《Chemistry (Weinheim an der Bergstrasse, Germany)》2015,21(14):5477-5487
We explore the influence of two solvents, namely water and the ionic liquid 1‐ethyl‐3‐methylimidazolium acetate (EmimAc), on the conformations of two cellulose models (cellobiose and a chain of 40 glucose units) and the solvent impact on glycosidic bond cleavage by acid hydrolysis by using molecular dynamics and metadynamics simulations. We investigate the rotation around the glycosidic bond and ring puckering, as well as the anomeric effect and hydrogen bonds, in order to gauge the effect on the hydrolysis mechanism. We find that EmimAc eases hydrolysis through stronger solvent–cellulose interactions, which break structural and electronic barriers to hydrolysis. Our results indicate that hydrolysis in cellulose chains should start from the ends and not in the centre of the chain, which is less accessible to solvent. 相似文献
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Walter N. Harrington Christina M. Kackos Richard J. Webby 《Experimental & molecular medicine》2021,53(5):737
The influenza virus is a global threat to human health causing unpredictable yet recurring pandemics, the last four emerging over the course of a hundred years. As our knowledge of influenza virus evolution, distribution, and transmission has increased, paths to pandemic preparedness have become apparent. In the 1950s, the World Health Organization (WHO) established a global influenza surveillance network that is now composed of institutions in 122 member states. This and other surveillance networks monitor circulating influenza strains in humans and animal reservoirs and are primed to detect influenza strains with pandemic potential. Both the United States Centers for Disease Control and Prevention and the WHO have also developed pandemic risk assessment tools that evaluate specific aspects of emerging influenza strains to develop a systematic process of determining research and funding priorities according to the risk of emergence and potential impact. Here, we review the history of influenza pandemic preparedness and the current state of preparedness, and we propose additional measures for improvement. We also comment on the intersection between the influenza pandemic preparedness network and the current SARS-CoV-2 crisis. We must continually evaluate and revise our risk assessment and pandemic preparedness plans and incorporate new information gathered from research and global crises.Subject terms: Influenza virus, Infectious diseases 相似文献
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We prove the existence of global smooth solutions near a given steady state of the hydrodynamic model of the semiconductors
in a bounded domain with physical boundary conditions. The steady state and the doping profile are permitted to be of large
variation but the initial velocity must be small. Two cases are considered. In the first one the problem is three-dimensional,
the boundary conditions are insulating and the steady state velocity vanishes. In the second one, the problem is one-dimensional,
the boundary is of contact type and the steady state velocity does not vanish. 相似文献
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Hendrik Van Maldeghem 《Journal of Geometry》1997,58(1-2):192-202
We characterize in a geometrical way those Suzuki-Tits ovoids which are defined over a perfect fieidK (or equivalently living inside a self polar symplectic quadrangle). We simplify our axioms in the particular cases that (1) the associated Suzuki group has exactly two orbits in the set of lines ofPG(3,K), and (2) the ovoid is finite.Senior Research Associate at the Belgian National Fund for Scientific Research 相似文献