全文获取类型
收费全文 | 1531篇 |
免费 | 174篇 |
国内免费 | 234篇 |
专业分类
化学 | 1184篇 |
晶体学 | 13篇 |
力学 | 125篇 |
综合类 | 20篇 |
数学 | 124篇 |
物理学 | 473篇 |
出版年
2024年 | 3篇 |
2023年 | 23篇 |
2022年 | 39篇 |
2021年 | 29篇 |
2020年 | 55篇 |
2019年 | 46篇 |
2018年 | 48篇 |
2017年 | 31篇 |
2016年 | 80篇 |
2015年 | 65篇 |
2014年 | 71篇 |
2013年 | 116篇 |
2012年 | 113篇 |
2011年 | 129篇 |
2010年 | 90篇 |
2009年 | 79篇 |
2008年 | 98篇 |
2007年 | 99篇 |
2006年 | 89篇 |
2005年 | 66篇 |
2004年 | 66篇 |
2003年 | 43篇 |
2002年 | 48篇 |
2001年 | 38篇 |
2000年 | 29篇 |
1999年 | 45篇 |
1998年 | 49篇 |
1997年 | 39篇 |
1996年 | 29篇 |
1995年 | 22篇 |
1994年 | 28篇 |
1993年 | 25篇 |
1992年 | 26篇 |
1991年 | 22篇 |
1990年 | 16篇 |
1989年 | 6篇 |
1988年 | 9篇 |
1987年 | 7篇 |
1986年 | 4篇 |
1985年 | 4篇 |
1984年 | 2篇 |
1983年 | 6篇 |
1981年 | 1篇 |
1978年 | 1篇 |
1975年 | 1篇 |
1973年 | 3篇 |
1971年 | 1篇 |
排序方式: 共有1939条查询结果,搜索用时 15 毫秒
1.
Development of an LC‐MS/MS method for determining the pharmacokinetics of clonidine following oral administration of Zhenju antihypertensive compound
下载免费PDF全文
![点击此处可从《Biomedical chromatography : BMC》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Jing Qin Limin Wang Lihong Wu Jun Chen Teng Shen Yongji Li Limei Han Jianxin Wang 《Biomedical chromatography : BMC》2015,29(7):1068-1075
Zhenju antihypertensive compound (ZJAHC) is a combined Chinese–Western medicine formula including clonidine (CLO), hydrochlorothiazide (HCT), rutin, Chrysanthemum indicum extract and pearl powder. Compared with CLO preparations, ZJAHC shows improved activities and decreased adverse effects. It is believed that the side effects of CLO are caused by its high peak plasma concentration. Hence, study of the influence of ZJAHC on the pharmacokinetic behaviors of clonidine seems essential. In present study, the plasma concentrations of CLO were determined with a liquid chromatography–tandem mass spectrometry (LC‐MS/MS) method. The MS/MS transitions monitored for clonidine and internal standard were 230.2 → 213.1 and 152.2 → 110.2, respectively. The analyte was quantified in a single run within 3 min. The pharmacokinetic study showed that the area under the plasma concentration–time curve of CLO in ZJAHC (60 µg/kg CLO) was similar to that of CLO‐HCT‐high (120 µg/kg CLO) but the peak concentration was much lower than that in CLO‐HCT‐high. ZJAHC could enhance the bioavailability without greatly increasing peak concentration of clonidine. This comprehensive effect of enhancing the bioavailability and avoiding the high peak plasma concentration for CLO might mainly result from the co‐contribution of Western medicine and traditional Chinese medicine (TCM), while the effect of TCM was stronger than that of Western medicine. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
2.
利用Riccati变换求解同谐谐振子的定态薛定谔方程,求得了能谱及态函数
关键词:
同调谐振子
本征值谱
Riccati变换法 相似文献
3.
本文介绍一种用牛顿力学研究赛跑运动的物理模型,给出两种情形下跑步时间的最优化结果.这一结果与优秀运动员的实际比赛成绩很好地相符. 相似文献
4.
5.
具有某种断面的半群的研究进展 总被引:1,自引:0,他引:1
本文综述了几类具有特殊断面的半群的近期研究结果。在介绍逆半群和正则半群的一般结构之后,概述了具有逆断面的正则半群的结构和同余格的研究成果。总结了作为逆断面的推广的可裂断面,纯正断面,正则^*-断面和恰当断面。提出了可以进一步研究的重要的问题。 相似文献
6.
从立方抛物线谈起(1)--余弦型振动,椭圆余弦型振动与双曲线型非周期运动 总被引:1,自引:1,他引:0
从立方抛物线的特性谈起 ,用较初浅的方法 ,借助于雅可比椭圆函数求椭圆方程的解来说明一大类一维保守系统的余弦振动、椭圆余弦型振动与双曲线型非周期运动 .并以杜芬振子、单摆、倒摆、转动圆环上的小环运动为典型实例作了详细讨论 相似文献
7.
8.
Microstructure effect on chemical etching behavior of the annealed Ti-6Al-4V and Ti-3Al-2.5V titanium (Ti) alloys was compared with that of unalloyed commercially pure titanium. The microstructural evolution of structure phases after annealing the titanium and its alloys at temperature near and above β transus and followed by furnace cooling to room temperature was studied using optical microscope, scanning electron microscope and X-ray diffraction techniques. The microstructure study illustrates that the heat treatment enhanced partitioning effect allows extensive formation of hemispherical and near spherical pits roughened surface to be readily acquired by chemically etching the annealed α + β titanium alloys. The kinetics of the chemical etching reaction process show a linear dependence on time. The annealed α + β titanium alloys that exhibit relatively lower weight loss and thickness reduction rate illustrate less chemical activity than the annealed unalloyed titanium. 相似文献
9.
A hierarchical structure (HS) analysis (β-test and γ-test) is applied to a fully developed turbulent pipe flow. Velocity signals are measured at two cross sections in the pipe and at a series of radial locations from the pipe wall. Particular attention is paid to the variation of turbulent statistics at wall units 10<y+<3000. It is shown that at all locations the velocity fluctuations satisfy the She–Leveque hierarchical symmetry (Phys. Rev. Lett. 72 (1994) 336). The measured HS parameters, β and γ, are interpreted in terms of the variation of fluid structures. Intense anisotropic fluid structures generated near the wall appear to be more singular than the most intermittent structures in isotropic turbulence and appear to be more outstanding compared to the background fluctuations; this yields a more intermittent velocity signal with smaller γ and β. As turbulence migrates into the logarithmic region, small-scale motions are generated by an energy cascade and large-scale organized structures emerge which are also less singular than the most intermittent structures of isotropic turbulence. At the center, turbulence is nearly isotropic, and β and γ are close to the 1994 She–Leveque predictions. A transition is observed from the logarithmic region to the center in which γ drops and the large-scale organized structures break down. We speculate that it is due to the growing eddy viscosity effects of widely spread turbulent fluctuations in a similar way as in the breakdown of the Taylor vortices in a turbulent Couette–Taylor flow at high Reynolds numbers. 相似文献
10.