Expert systems for HPLC in biochemistry—The knowledge base for selection of HPLC column system in the separation of amino acids,peptides and proteins

The strategy of expert system for high performance liquid chromatography was discussed, the attentions are mainly placed on the knowledge base for selection of column system, separation modes and detection modes in the analysis of amino acids, peptides and proteins.     

The relation between chemical structure of dicarboxylic dihydrazide compounds and nucleation effect in isotactic polypropylene

Journal of Thermal Analysis and Calorimetry - A series of dicarboxylic dihydrazide compounds (DCDH-R-n) were prepared and used as nucleating agents for isotactic polypropylene (iPP). To investigate...     

Thermal stability of nucleation effect of different β-nucleating agents in isotactic polypropylene

Journal of Thermal Analysis and Calorimetry - The thermal stability of nucleation effect of three highly effective β-nucleating agents, namely an aryl diamide-based nucleating agent (TMB-5), a...     

细内径高效液相色谱柱

本文采用自制的专门设计的柱系统可使“边壁效应”减至最小.不同溶质在不同内径的柱子上其保留体积V_R和峰宽(体积单位)间有一近似的线性关系,2△V_1/2=a’+b’V_R. 文中系统考查了鉴定器系统体积对a’和b’值的影响,指出鉴定器系统的体积对a’值有很大的影响,而对b’值几乎没有什么影响.使用改进的柱系统和自制的紫外鉴定器.在2毫米内径10厘米长的柱子上获得了6000理论塔板数.     

The principle of optimization of binary mobile phase composition of multi-step linear gradient elution

The basic principle of optimal method called “moving overlapping resolution mapping method” to select the optimal binary mobile phase composition of multi-step linear gradient liquid chromatography is discussed with simultaneously considering effects of position of solute inside the column and mobile phase composition on peak resolution and retention value, then a BASIC program based on this principle is developed in IBM-PC computer. The validities of both principle of optimization and BASIC program are confirmed by separation of samples containing bile acids and PAHs in RP-HPLC.     

气相色谱固定液极性和选择性评价

对非同族化合物溶质在两种固定相上保留值的关系进行了理论推导，并将该方程应用于８９种常见固定相的极性和选择性的评价。固定相的极性可用Ｂ值来评价，而选择性则用Ｂ、Ｔ３＾ａ，Ｃ３β值来评价。用该方程评价固定相具有两个优点，一是基于分子间作用力来评价固定相；二是探针化合物的选择不再受限制。     

Nucleus density and crystallization behavior of isotactic polypropylene nucleated with different α/β compound nucleating agents

Journal of Thermal Analysis and Calorimetry - Different compound nucleating agents consisting of a highly efficient novel α-nucleating agent N,N’-bis(benzoyl) sebacic acid dihydrazide...     

柱色谱多元组份分离的理论基础

本文用以前发表的方法评价了由我所发展的、并已在我国生产的微粒填料(硅胶及化学键合硅胶),得到具有每10厘米柱长1,400到10,000理论塔片(对HPLC)和每10厘米柱长1,800到4,400理论塔片(对GC)的柱效。并给出了改变硅胶表面积和冲洗组成时,不同物质容量因子的线性关系以及HPLC和HPGC的块速色谱图。     

新型微填充柱-毛细管柱二维色谱系统的理论研究(Ⅱ)──双柱条件对柱效的影响

从色谱动力学角度探讨了改变微填充柱-毛细管柱二维色谱系统中双柱条件对柱效的影响规律,进一步证实了短填充柱接长毛细管柱及高预柱柱温、快预柱载气线速有利于提高双柱系统柱效的结论;同时,通过对主柱柱温、载气线速及柱间分流比的讨论,从理论和实验上也证实了相对较低的主柱柱温、较慢主柱线速以及稍大的分流比有益于柱效利用率的提高。