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排序方式: 共有66条查询结果,搜索用时 31 毫秒
1.
Amirhossein Nazhand Alessandra Durazzo Massimo Lucarini Maria Alessandra Mobilia Besma Omri 《Natural product research》2020,34(1):110-121
AbstractTaxol is one of the anticancer drugs synthesized naturally in the evergreen Taxus brevifolia forest tree belonging to the yew family (Taxaceae) growing on the Pacific. There are reportedly evidence for treating ovarian, breast and lung cancers through this drug given its unique structural and functional features. Extraction of this drug from yew trees bark is one of the most common ways of producing this drug, but 3000 trees are needed to obtain a kilogram of Taxol. Hence, further attention has recently been attracted to the metabolic engineering strategies, including, engineering cellular metabolism of microorganisms and their optimization. Accordingly, the present paper article was aimed to review recent advances in elevating the production and commercialization of Taxol through metabolic engineering techniques. 相似文献
2.
Dr. Itai Carmeli Dr. Karuppannan Senthil Kumar Omri Heifler Prof. Chanoch Carmeli Prof. Ron Naaman 《Angewandte Chemie (International ed. in English)》2014,53(34):8953-8958
Photosystem I (PSI) is one of the most studied electron transfer (ET) systems in nature; it is found in plants, algae, and bacteria. The effect of the system structure and its electronic properties on the electron transfer rate and yield was investigated for years in details. In this work we show that not only those system properties affect the ET efficiency, but also the electrons’ spin. Using a newly developed spintronic device and a technique which enables control over the orientation of the PSI monolayer relative to the device (silver) surface, it was possible to evaluate the degree and direction of the spin polarization in ET in PSI. We find high‐spin selectivity throughout the entire ET path and establish that the spins of the electrons being transferred are aligned parallel to their momenta. The spin selectivity peaks at 300 K and vanishes at temperatures below about 150 K. A mechanism is suggested in which the chiral structure of the protein complex plays an important role in determining the high‐spin selectivity and its temperature dependence. Our observation of high light induced spin dependent ET in PSI introduces the possibility that spin may play an important role in ET in biology. 相似文献
3.
Selfquenching of the photocapacitance and of the reverse photocurrent in Schottky diodes made on dislocatedn-type silicon was discovered. A phenomenological model explaining this, rather unexpected, phenomenon is proposed. The model requires an introduction of a new mechanism of diode conductance via dislocation lines. Crucial for this mechanism is the possibility of electron tunneling from dislocation to the conduction band. 相似文献
4.
Light is shown to exhibit critical and tricritical behavior in passively mode-locked lasers with externally injected pulses. It is a first and unique example of critical phenomena in a one-dimensional many-body light-mode system. The phase diagrams consist of regimes with continuous wave, driven parapulses, spontaneous pulses via mode condensation, and heterogeneous pulses, separated by phase transition lines that terminate with critical or tricritical points. Enhanced non-Gaussian fluctuations and collective dynamics are present at the critical and tricritical points, showing a mode system analog of the critical opalescence phenomenon. The critical exponents are calculated and shown to comply with the mean field theory, which is rigorous in the light system. 相似文献
5.
We classify the ergodic invariant Radon measures for the horocycle flow on geometrically infinite regular covers of compact
hyperbolic surfaces. The method is to establish a bijection between these measures and the positive minimal eigenfunctions
of the Laplacian of the surface. Two consequences arise: if the group of deck transformations G is of polynomial growth, then these measures are classified by the homomorphisms from G
0 to ℝ where G
0 ≤ G is a nilpotent subgroup of finite index; if the group is of exponential growth, then there may be more than one Radon measure
which is invariant under the geodesic flow and the horocycle flow. We also treat regular covers of finite volume surfaces.
The first author was supported by NSF grant 0500630.
The second author was supported by NSF grant 0400687. 相似文献
6.
7.
We present an experimental study of the stability of passively mode-locked pulses against noise in multipulse operation of an erbium-doped fiber laser. The laser properties are determined by two dimensionless combinations of the laser parameters. Measurements of the pulses' destabilization threshold as a function of those laser parameters show the optimal regions that maximize the mode-locked pulse stability. We find good agreement between the experimental observations and the theoretical predictions. 相似文献
8.
Let Γ be a torsion-free hyperbolic group. We study Γ-limit groups which, unlike the fundamental case in which Γ is free, may not be finitely presentable or geometrically tractable. We define model Γ-limit groups, which always have good geometric properties (in particular, they are always relatively hyperbolic). Given a strict resolution of an arbitrary Γ-limit group L, we canonically construct a strict resolution of a model Γ-limit group, which encodes all homomorphisms L → Γ that factor through the given resolution. We propose this as the correct framework in which to study Γ-limit groups algorithmically. We enumerate all Γ-limit groups in this framework. 相似文献
9.
We classify deformations of the standard embedding of the Lie superalgebra $
\mathcal{K}
$
\mathcal{K}
(2) of contact vector fields on the (1, 2)-dimensional supercircle into the Lie superalgebra SΨD(S
1|2
) of pseudodifferential operators on the supercircle S
1|2
. The proposed approach leads to the deformations of the central charge induced on $
\mathcal{K}
$
\mathcal{K}
(2) by the canonical central extension of SΨD(S
1|2
). 相似文献
10.
First we study the Gauss and Poisson semigroups connected with the spherical mean operator. Next, we define and study the Littlewood– Paley g-function associated with the spherical mean operator for which we prove the L p -boundedness for ${p \in]1, 2]}$ . 相似文献