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排序方式: 共有97条查询结果,搜索用时 15 毫秒
1.
D. V. Shishkin A. R. Shaimuratova A. N. Lobov N. Z. Baibulatova L. V. Spirikhin M. S. Yunusov N. S. Makara N. Zh. Baschenko V. A. Dokichev 《Chemistry of Natural Compounds》2007,43(2):190-196
Derivatives of N-(2-hydroxyethyl)cytisine, N-(2-hydroxypropyl)-, N-(2-hydroxy-2-(1-adamantyl)ethyl)-, and N-(2-hydroxy-2-phenylethyl)cytisine, were synthesized by reduction of N-(2-oxopropyl)-, N-(2-oxo-2-(1-adamantyl)ethyl)-and N-(2-oxo-2-phenylethyl)cytisine with metal hydrides. The antiarrhythmic and analgesic activities of the prepared compounds
were investigated.
__________
Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 157–162, March–April, 2007. 相似文献
2.
3.
Inna P. Tsypysheva Alexander N. Lobov Alena V. Kovalskaya Valentina I. Vinogradova Kyrill Yu. Suponitsky Sergey L. Khursan Marat S. Yunusov 《Tetrahedron: Asymmetry》2013,24(20):1318-1323
The Diels–Alder adducts of the quinolizidine alkaloids N-methylcytisine, (?)-leontidine, and (?)-thermopsine with N-phenylmaleimide have been synthesized. The structures and absolute configurations of the new asymmetric centers of the products were determined by NMR spectroscopy experiments, QC-calculations, and X-ray data. 相似文献
4.
Akhiyarov A. A. Lobov A. N. Chernikova I. B. Ivanov S. P. 《Russian Journal of General Chemistry》2022,92(2):154-160
Russian Journal of General Chemistry - The constants of acid-base equilibrium of 6-methyluracil-5-carbonitrile in water were determined spectrophotometrically. For the first time,... 相似文献
5.
Valiullina Z. R. Ivanova N. A. Lobov A. N. Miftakhov M. S. 《Russian Journal of Organic Chemistry》2020,56(11):2043-2047
Russian Journal of Organic Chemistry - Methyl (E)-3-[(4S,5S)-5-acetyl-2,2-dimethyl-1,3-dioxolan-4-yl)]prop-2-enoate obtained from D-ribose eliminates water on storage and transforms into a bicyclic... 相似文献
6.
Arseniy A. Lobov Natalia M. Yudintceva Alexey G. Mittenberg Sergey V. Shabelnikov Natalia A. Mikhailova Anna B. Malashicheva Mikhail G. Khotin 《Molecules (Basel, Switzerland)》2020,25(22)
Secretome of multipotent mesenchymal stromal cells (MSCs) is actively used in biomedical applications such as alveolar bone regeneration, treatment of cardiovascular disease, and neurodegenerative disorders. Nevertheless, hMSCs have low proliferative potential and production of the industrial quantity of their secretome might be challenging. Human fetal multipotent mesenchymal stromal cells (FetMSCs) isolated from early human embryo bone marrow are easy to expand and might be a potential source for pharmaceutical substances production based on their secretome. However, the secretome of FetMSCs was not previously analyzed. Here, we describe the secretome of FetMSCs using LC-MALDI shotgun proteomics. We identified 236 proteins. Functional annotation of the identified proteins revealed their involvement in angiogenesis, ossification, regulation of apoptosis, and immune response processes, which made it promising for biomedical applications. The proteins identified in the FetMSCs secretome are involved in the same biological processes as proteins from previously described adult hMSCs secretomes. Nevertheless, many of the common hMSCs secretome components (such as VEGF, FGF, Wnt and TGF-β) have not been identified in the FetMSCs secretome. 相似文献
7.
I. E. Smirnova H. Do Thi Thu O. B. Kazakova G. A. Tolstikov O. S. Kukovinets A. N. Lobov K. Yu. Suponitskii 《Russian Journal of Organic Chemistry》2012,48(10):1370-1376
Oxidation of dipterocarpol and its derivatives with ozone gave compounds containing lactone, lactol, alkoxytetrahydrofuran, aldehyde, and methyl ketone fragments in the side chain, as well as 1,2,4-trioxolane fragment in the A ring. The molecular and crystalline structures of dipterocarpol were determined by X-ray analysis. 相似文献
8.
L. A. Aleshina A. M. Kalinkin D. V. Lobov R. N. Osaulenko A. D. Fofanov 《Technical Physics》2010,55(7):981-984
The crystal structure of the perovskite rhombohedral modification before and after mechanoactivation in air and in carbon
dioxide is studied using the X-ray diffraction method. It is shown that a medium in which an as-grown perovskite crystal is
milled influences the degree of its amorphization but does not influence either the size of ordered areas or the distortion
of titanium and calcium coordination polyhedra. It is found that the rate of perovskite milling is smaller than the rate of
pseudowollastonite milling under the same conditions. 相似文献
9.
J. Andrzejewski N. A. Gundorin I. L. Karpikhin L. Lason G. A. Lobov D. V. Matveev L. B. Pikelner 《Physics of Atomic Nuclei》2004,67(7):1233-1238
The effect of parity violation in the interaction of thermal neutrons with lead was discovered in a number of studies. According to the existing theory, this effect is explained by the mixing of compound states characterized by different parities (s-and p-wave resonances). In view of the absence of a p-wave resonance in the region of thermal neutron energies, it is of importance to reveal a level below the neutron binding energy, a so-called negative resonance. The energy dependence of the cross section for radiative neutron capture on lead was measured in the present study, and it is shown that, for the 207Pb isotope, the results of this measurement deviate from the \({1 \mathord{\left/ {\vphantom {1 {\sqrt E }}} \right. \kern-\nulldelimiterspace} {\sqrt E }}\) law, thereby suggesting the presence of a strong negative resonance. The parameters of this resonance are estimated. 相似文献
10.
D. V. Shishkin N. Z. Baibulatova A. N. Lobov S. P. Ivanov L. V. Spirikhin V. A. Dokichev 《Chemistry of Natural Compounds》2010,46(1):62-65
Diastereomers of N(12)-(2-hydroxy-2-phenylethyl)cytisine were synthesized by reduction of N(12)-(2-oxo-2-phenylethyl)cytisine
by Yamamoto reagent. Their structures were solved using x-ray structure analysis. 相似文献