排序方式: 共有18条查询结果,搜索用时 15 毫秒
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Sajida Khanum 《Tetrahedron letters》1984,25(35):3913-3916
Studies on the alkaloids in the leaves of Rhazya stricta have resulted in the isolation of a new alkaloid “rhazimine” (2) bearing a novel skeletal system closely related to the ajmaline group of alkaloids. 相似文献
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Mahendra Madegowda Doreswamy Beeranahally H. Sridhar Mandayam A. Prasad Javaregowda S. Khanum Shaukath A. Shashikanth Sheena Sudha Belagur S. 《Structural chemistry》2004,15(3):211-214
Benzophenone analog 3 has been synthesized and characterized by the X-ray diffraction (XRD) method. The compound crystallizes in a monoclinic space group P21/c with cell parameters a = 7.701(8) Å, b = 7.151(5) Å, c= 28.323(3) Å, = 104.639(4)°, Z = 4. The structure exhibits intra- and intermolecular hydrogen bonding of the type N–HO, C–HO, and N–HN. The molecules are interlinked through hydrogen bonds forming an infinite chain. This polymeric-like structure may play an important role in biological activity. 相似文献
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Zabiulla S. Naveen A. Bushra Begum Shaukath Ara Khanum 《Molecular Crystals and Liquid Crystals》2016,625(1):233-237
The title compound (4-Chloro-2-hydroxy-phenyl)-phenyl-methanone was synthesized and the product obtained was characterized by spectroscopic techniques, and finally the structure was confirmed by X-ray diffraction studies. The compound crystallizes in the orthorhombic crystal system with the space group Pbca with unit cell parameters, a = 14.0359(5) Å, b = 6.8084(3) Å, c = 23.1097(8) Å, and Z = 4. The structure exhibits an intramolecular hydrogen bond which closes an S(6) ring. No directional interactions beyond the van der Waals packing contacts were identified in the crystal structure. 相似文献
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Nallamuthu Ilaiyaraja Ponnusamy Vinithra Smruthi M. R. Khanum Farhath 《Journal of Cluster Science》2021,32(6):1649-1662
Journal of Cluster Science - Naringin, a dietary flavonoid of citrus fruits, was encapsulated in biodegradable proteins of zein/casein biopolymers for its enhanced functional properties. The... 相似文献
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In this study, we present linear analysis of electrostatic counter-streaming instability in spin-polarized electron–positron–ion (e-p-i) plasma. With the aid of the separate spin evolution-quantum hydrodynamic (SSE-QHD) model, we derive the dispersion relation of counter-streaming instability. We numerically solve the dispersion and find four wave solutions: Langmuir wave, positron acoustic mode, and two electron and positron spin-dependent waves. It is noted that coupling of streaming and spin effects excites Langmuir instability and positron acoustic mode instability. However, in the absence of spin effect, only Langmuir instability will survive in e-p-i plasma. We have also discussed the effects of positron concentration, streaming speed, and spin polarization on the real frequency of waves and the growth rate. The present study may be helpful for understanding longitudinal wave propagation and instabilities in dense magnetized environments. 相似文献
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Abstract— Wistar rats were injected with hematoporphyrin derivative (Hpd) intraperitoneally and kept in the dark. Rats were sacrificed 2, 24, 48 and 72 h after injection. It was observed that Hpd in the dark did not affect the hemoglobin content and number of erythrocytes, while the leukocyte count was increased and blood pH decreased. Blood levels of glucose and lactate were increased significantly. Because the food intake was similar in all the groups, glycogenolysis was suspected to be the source of increased glucose levels in blood. However, a significant increase in the glycogen content of the livers of Hpd-treated rats was observed, which rules out glycogenolysis. Hyperglycemia may result due to a number of reasons such as stimulation of the central nervous pathways innervating the liver and adrenal medulla, excessive glucogenesis in liver from glycogen and noncarbohydrate sources, emotional stress, anesthesia and hormonal effects. The present study rules out hyperglycemia due to anesthesia and glucogenesis in the liver. Maintenance of blood glucose levels is a highly complex mechanism. Further investigations to understand these mechanisms are in progress. 相似文献
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Effects of Photofrin II on energy metabolism and metabolic viability were studied in a mammalian transformed cell line (BHK-21) in dark and after photo-irradiation with visible light. Cells were allowed to accumulate Photofrin by incubating for 4 h in buffer containing Photofrin (5-60 micrograms/ml). The results show that Photofrin significantly affects the cellular energy metabolism even in the absence of light; activity of cytochrome c oxidase is decreased and glucose utilization and lactate production (glycolysis) are increased. Irradiation with light resulted in a significant decrease in the activity of cytochrome c oxidase, glycolysis, ATP content, energy charge, ratios of adenine nucleotides like ATP/ADP, ATP/AMP and cell viability (dye exclusion test). Presence of inhibitors of energy metabolism, potassium cyanide (respiration) and 2-deoxyglucose (glycolysis), further enhanced the cytotoxic effects induced by hematoporphyrin derivative and light. 相似文献
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Saify ZS Nisa M Azhar KF Azim MK Rasheed H Mushtaq N Arain MA Haider S Khanum M Ahmed W 《Natural product research》2011,25(20):1965-1968
Piperidine derivatives are reported to exhibit a variety of pharmacological activities. In this article, synthesis and aspartic protease inhibitory activity of three nitrophenacyl derivatives of N-methyl-4-hydroxy piperidine are reported. Enzyme assays showed that the attachment of a nitro group in the benzene ring plays an important role in the inhibition of plasmepsin-II of Plasmodium falciparum. The compound 1-methyl-1-(4'-nitrophenacyl)-4-hydroxypiperidinium bromide (3), consisting of a nitro group at the para position, was the most active at the concentration of 1.0?μM. The activity of the compounds was evaluated through the observed orientation and diagrammatic representation of nitrophenacyl derivatives of 4-hydroxy piperidine. 相似文献