有机张力半导体及其光电特性

分子张力作为空间设计的重要组成部分正成为调控有机半导体的重要手段。由于分子内产生的拉伸张力、扭曲/弯曲张力以及空间张力而导致p轨道排布重组和构型构象结构发生变化,最近各种几何与拓扑结构的高张力有机半导体材料相继被报道,这使得高张力有机半导体材料成为有机电子领域研究的焦点。为了进一步梳理分子张力在有机半导体材料中扮演的角色与价值,该综述从分子张力的类型、实验与理论量化以及可视化出发,总结了高张力共轭芳烃的分子设计策略、与其光电性能分子张力之间的关系,以及这类新兴材料在光电领域的应用。最后,对高张力共轭芳烃的研究前景进行了展望,阐述了该类材料所面临的机遇与挑战。     

N'-叔丁氨基羰基-N-(5-取代苯基-2-呋喃甲酰基)硫脲的合成及对白血病K562细胞增殖的影响

将活性基团5-取代苯基呋喃环和叔丁氨基引入酰基硫脲的分子骨架中,设计合成了8个未见文献报道的N'-叔丁氨基羰基-N-(5-取代苯基-2-呋喃甲酰基)硫脲类化合物(5a～5h),结构经元素分析、IR和 1H NMR等测试技术得到确证. 经MTT(溴化3-(4,5-二甲基噻唑-2-基)-2,5-二苯基四氮唑)法观察,首次发现目标化合物对白血病K562细胞的增殖有明显的抑制作用. 在药物浓度为100×10-6 g/mL时,大部分目标化合物对白血病K562细胞生长的抑制率超过了70%,化合物5a对白血病K562细胞生长的抑制率达到77.14%. 其中,目标化合物5f和5h对白血病K562细胞有诱导作用,进一步的测试正在进行中.     

N＇-乙氧羰基取代甲基-N-β-吡啶甲酰硫脲的合成及晶体结构

从α-L-氨基酸乙酯出发,设计合成了9种新N＇-乙氧羰基取代甲基-N-β-吡啶甲酰硫脲衍生物.其结构经IR,1H NMR,MS和元素分析测试确证.对化合物7d的单晶进行了X射线晶体结构测定,其属于单斜晶系,C2空间群,晶胞参数α=1.6912（6）nm,b=0.5197（19）nm,c=1.9399（7）nm,Z=4,V=1.6962（11）nm^3,Dc=1.266 Mg/m^3,α=90.00°,β=95.89°,γ=90.00°,F（000）=688,R=0.0667,wR=0.1709.经MTT法三次平行实验,首次发现部分目标化合物对白血病K562细胞的增殖有明显的抑制作用.     

N-[5-(2-氯苯基)-2-呋喃甲酰氨基硫羰基]-L-α-氨基酸乙酯的合成与生物活性测定

设计并合成了9种未见文献报道的N-(5-邻氯苯基-2-呋喃甲酰氨基硫羰基)-L-α-氨基酸乙酯衍生物,其结构经IR,1H NMR,MS和元素分析测试确证.MTT法测试结果表明大部分目标化合物对白血病K562细胞系的增殖具有明显的抑制作用.     

柱水滑石（Ⅰ）ZnAl-La(TiW11)2的合成、表征及其催化性能

柱水滑石（Ⅰ）ZnAl-La(TiW11)2的合成、表征及其催化性能;稀土杂多配离子;柱撑水滑石;合成;表征;催化性能     

N-(5-邻氯苯基-2-呋喃甲酰基)甘氨酰胺及酰肼类衍生物的合成与生物活性

甘氨酸;邻氯苯基呋喃甲酸;酰胺;酰肼;衍生物;合成;K562细胞;MTT比色法     

Synthesis, Crystal Structure and Inhibition of the K562 Cell Proliferation of N＇-Tertbutylaminocarbonyl-N-2-chlorophenoxyacetylthiourea

The title compound N'-tert-butylaminocarbonyl-N-2-chlorophenoxyacetylthiou- rea has been synthesized for the first time. Complete assignments were achieved by IR, 1H NHR and single-crystal X-ray diffraction analyses. The inhibitory rate of the cellular growth of K562 cells (chronic myeloid 1eukemic cells) was measured using MTT [3-(4,5-dimethylthiazo-2-y1)-2,5-di- phenyltetra-zolium bromide] assay. The cell apoptosis was assessed by agarose gel electrophoresis to find that the title compound has antiproliferation and apoptosis inducing effects on K562 cells. In order to investigate the relationship between structure and activity of the target compound, we report its crystal structure and biological behavior in the present paper. Crystallographic data: C14H18- ClN3O3S, Mr = 343.82, orthorhombic, space group Pnma, a = 19.786(6), b = 6.789(2), c = 12.938(4) , V = 1738.0(9) 3, Z = 4, Dc = 1.314 g/cm3, F(000) = 720, μ(MoKα) = 0.354 mm-1, R = 0.0378 and wR = 0.0941. The molecule is a planar structure.     

Newton’s Method for M-Tensor Equations

Journal of Optimization Theory and Applications - We are concerned with the tensor equations whose coefficient tensors are M-tensors. We first propose a Newton method for solving the equation with...     

Synthesis, Crystal Structure and Inhibition of N-2-Thiophenesulfonyl-α-L-phenylalanine Ethyl Ester on K562 Cell Proliferation

The title compound N-2-thiophenesulfonyl-α-L-phenylalanine ethyl ester has been synthesized. Complete assignments were achieved by IR, MS, 1H NMR and single-crystal X-ray diffraction analyses. Using MTT assay, the inhibitory rate of the title compound on K562 cells (chronic myeloid 1eukemic cells) was measured and the result of preliminary bioassay showed that the title compound possesses antiproliferation effects on K562 cells. In order to investigate the relationship between structure and activity of the target compound, we report its crystal structure and biological behavior in the present paper. Crystallographic data: C15H17NO4S2, Mr = 339.42, monoclinic, space group P21, flack = –0.15(12), a = 5.7916(10), b = 11.5078(19), c = 12.924(2) , β = 97.781(3)o, Z = 2, V = 853.4(2) 3, Dc = 1.321 g/cm3, F(000) = 356, –7≤h≤7, –10≤k≤14, –15≤l≤15, R = 0.0628, wR = 0.1540 and μ(MoKα) = 0.327 mm-1. The molecule comprises a benzene and a thiofuran rings, and the intramolecular N(1)–H(1A)…O(1) makes a five-membered ring of O(1)–C(6)–C(5)–N(1)–H(1A).     

Nijenhuis Operators on n-Lie Algebras

In this paper, we study (n-1)-order deformations of an n-Lie algebra and introduce the notion of a Nijenhuis operator on an n-Lie algebra, which could give rise to trivial deformations. We prove that a polynomial of a Nijenhuis operator is still a Nijenhuis operator. Finally, we give various constructions of Nijenhuis operators and some examples.