全文获取类型
收费全文 | 103篇 |
免费 | 10篇 |
国内免费 | 2篇 |
专业分类
化学 | 68篇 |
晶体学 | 1篇 |
力学 | 5篇 |
数学 | 15篇 |
物理学 | 26篇 |
出版年
2024年 | 1篇 |
2023年 | 4篇 |
2022年 | 11篇 |
2021年 | 10篇 |
2020年 | 2篇 |
2019年 | 4篇 |
2018年 | 5篇 |
2017年 | 2篇 |
2016年 | 5篇 |
2015年 | 3篇 |
2014年 | 6篇 |
2013年 | 7篇 |
2012年 | 7篇 |
2011年 | 6篇 |
2010年 | 11篇 |
2009年 | 5篇 |
2008年 | 3篇 |
2007年 | 5篇 |
2006年 | 4篇 |
2003年 | 1篇 |
2002年 | 1篇 |
2001年 | 1篇 |
2000年 | 1篇 |
1997年 | 1篇 |
1996年 | 2篇 |
1995年 | 2篇 |
1993年 | 1篇 |
1991年 | 2篇 |
1987年 | 1篇 |
1971年 | 1篇 |
排序方式: 共有115条查询结果,搜索用时 31 毫秒
1.
Bolis Basit Hans Gü nzler 《Transactions of the American Mathematical Society》1996,348(11):4489-4500
Let be a semigroup and a topological space. Let be an Abelian topological group. The right differences of a function are defined by for . Let be continuous at the identity of for all in a neighbourhood of . We give conditions on or range under which is continuous for any topological space . We also seek conditions on under which we conclude that is continuous at for arbitrary . This led us to introduce new classes of semigroups containing all complete metric and locally countably compact quasitopological groups. In this paper we study these classes and explore their relation with Namioka spaces.
2.
This article provides a critical review of the different applications of ferrocene‐based peptides/amides in biological as well as in non‐biological systems. Ferrocene‐based peptides/amides find many applications in different fields such as materials science, medicine, organic synthesis, bio‐organometallic and biological chemistry, asymmetric catalysis, nonlinear optics, in polymer science as redox active polymers and dendrimers, in molecular recognition as biosensors and in electrochemistry). Extensive research is being done on ferrocene‐based peptides/amides but we will highlight the various applications of ferrocene‐based peptides/amides for the period 2006–2010. The main factors that govern the potential biological and non‐biological applications are an electroactive core, a conjugated linker that can act as a chromophore and lower the oxidation potential of the ferrocene part, an amino acid or peptide derivative that can interact with other molecules via hydrogen bonding or any secondary bonding, and symmetric and asymmetric substitution on the ferrocene moiety. Copyright © 2011 John Wiley & Sons, Ltd. 相似文献
3.
A Small‐Molecule FRET Reporter for the Real‐Time Visualization of Cell‐Surface Proteolytic Enzyme Functions 下载免费PDF全文
Jing Mu Dr. Fang Liu Muhammad Shafiq Rajab Meng Shi Shuang Li Chiching Goh Prof. Lei Lu Prof. Qing‐Hua Xu Prof. Bin Liu Dr. Lai Guan Ng Prof. Bengang Xing 《Angewandte Chemie (International ed. in English)》2014,53(52):14357-14362
Real‐time imaging of cell‐surface‐associated proteolytic enzymes is critical to better understand their performances in both physiological and pathological processes. However, most current approaches are limited by their complexity and poor membrane‐anchoring properties. Herein, we have designed and synthesized a unique small‐molecule fluorescent probe, which combines the principles of passive exogenous membrane insertion and Förster resonance energy transfer (FRET) to image cell‐surface‐localized furin‐like convertase activities. The membrane‐associated furin‐like enzymatic cleavage of the peptide probe leads to an increased fluorescence intensity which was mainly localized on the plasma membrane of the furin‐expressed cells. This small‐molecule fluorescent probe may serve as a unique and reliable reporter for real‐time visualization of endogenous cell‐surfaceassociated proteolytic furin‐like enzyme functions in live cells and tissues using one‐photon and two‐photon microscopy. 相似文献
4.
Dr. Kai Lin Woon Siti Aisyah Syaerah Mustapa Nor Shafiq Mohd Jamel Dr. Vannajan Sanghiran Lee Muhammad Zhafran Zakaria Dr. Azhar Ariffin 《Chemphyschem》2020,21(22):2620-2626
Material designs that use donor and acceptor units are often found in organic optoelectronic devices. Molecular level insight into the interactions between donors and acceptors are crucial for understanding how such interactions can modify the optical properties of the organic optoelectronic materials. In this paper, tris(4-(tert-butyl)phenyl)amine (pTPA) was synthesized as a donor in order to compare with unmodified triphenylamine (TPA) in a donor–acceptor system by having 2,4,6-triphenyl-1,3,5-triazine (TRZ) as an acceptor. Dimerization of donors and acceptors occurred in solvent when the concentration of solute is high. At 0 K, using a polarizable continuum model, the nitrogen atom of TPA is found to stack on top of the center of triazine of TRZ, whereas such alignment is offset in pTPA and TRZ. We attributed such alignment in TPA-TRZ as the result of attractive interactions between partial localization of 2pz electrons at the nitrogen atom of TPA and the π deficiency of triazine in TPA-TRZ. By taking into account random motions of the solvent effect at 300 K in quantum molecular dynamics and classical molecular dynamics simulations to interpret the marked difference in emission spectra between TPA-TRZ and pTPA-TRZ, it was revealed that the attractive interaction between pTPA and TRZ in toluene is weaker than TPA and TRZ. Because of the weaker attractive interaction between pTPA and TRZ in toluene, the dimers adopted numerous ground state conformations resulting in broad emission bands superimposed with multiple small Gaussian peaks. This is in contrast to TPA-TRZ which has only one dominant dimer conformation. This study demonstrates that the strength of intermolecular interactions between donors and acceptors should be taken into consideration in designing supramolecular structures. 相似文献
5.
6.
Y. F. Shafiq 《Journal of Radioanalytical and Nuclear Chemistry》1995,196(1):113-123
(6-3H)-Thymidine, (5-3H)-methyl-thymidine, and (5′-3H)-thymidine were synthesized by the use of tritiated water. The specific activities of the products were 3.3, 3.4 and 3.0 mCi/mM, respectively. These tritiated thymidines are important tracers to study human lymphocytes and human chromosomes. 相似文献
7.
8.
9.
Yousif F. Shafiq 《Journal of Saudi Chemical Society》2010,14(1):139-145
Protein binding affects tissue distribution, plasma clearance and uptake of renal radiopharmaceuticals. The 99mTc bound to plasma protein after incubation 99mTc-Gluco-ene-diolate (99mTc-Sn-Gluco) agent or 99mTc-prylidinomethyl-tetracycline (99mTc-Sn-PMT) agent with plasma protein. It was observed that the protein bound to 99mTc is lesser extent with (99mTc-Sn-Gluco) agent than with the 99mTc-PMT agent. 99mTc-Sn-PMT is excreted more rapidly than 99mTc-Sn-Gluco. On the other hand the percentage binding to protein seems to depend on the origin of the protein and or the type of protein (human or animal). However lower human protein binding or higher protein binding were observed with 99mTc-Sn-Gluco or with 99mTc-Sn-PMT, respectively compared with the binding to rat protein. The unbroken down of the chemical form of the origin of these two agents and the highest of 99mTc-Sn-Gluco remained as origin in urine indicate that 99mTc-Sn-Gluco are more stable than 99mTc-Sn-PMT.Concerning the type of protein binding to 99mTc-Sn-PMT or to 99mTc-Sn-Gluco, it was observed that Human Plasma Protein is greater binding than Human serum protein or than IgG. 相似文献
10.
Khaula Shirin Saima Imad Sheraz Shafiq Kaneez Fatima 《Journal of Saudi Chemical Society》2010,14(1):97-100
Withania somnifera (family Solanaceae) has been studied to determine major and trace elements and their possible correlation with therapeutic value of the plant. Nine trace elements were determined in Withania somnifera. This important medicinal plant was found to be rich in Fe, Cu, Ni, Mn, and Zn. These trace elements are well known for curing diseases. The plant contains nutrient elements, which are best sources for fodder. 相似文献