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Bartomiej Piasecki Anna Biernasiuk Adrianna Skiba Krystyna Skalicka-Wo
niak Agnieszka Ludwiczuk 《Molecules (Basel, Switzerland)》2021,26(24)
Many of the essential oils obtained from medicinal plants possess proven antimicrobial activity and are suitable for medicinal purposes and applications in the food industry. The aim of the present work was the chemical analysis of 19 essential oils (EOs) from seven different Cymbopogon species (C. nardus, C. citratus, C winterianus, C. flexuosus, C. schoenanthus, C. martinii, C. giganteus). Five different chemotypes were established by GC/MS and TLC assay. The EOs, as well as some reference compounds, i.e., citronellol, geraniol and citral (neral + geranial), were also tested for their antimicrobial and antibiofilm activity against methicillin-resistant Staphylococcus aureus (MRSA) by the microdilution method and direct bioautography. The toxicity of EOs was evaluated by Danio rerio ‘Zebrafish’ model assay. All examined EOs showed moderate to high activity against MRSA, with the highest activity noted for C. flexuosus—lemongrass essential oil, both in microdilution and direct autobiography method. Significant difference in the toxicity of the examined EOs was also detected. 相似文献
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Adrianna Pach Agnieszka Podborska Edit Csapo Magdalena Luty-Bocho 《Molecules (Basel, Switzerland)》2022,27(14)
The selective determination of metals in waste solutions is a very important aspect of the industry and environmental protection. Knowledge of the contents and composition of the waste can contribute to design an efficient process separation and recovery of valuable metals. The problematic issue is primarily the correct determination of metals with similar properties such as palladium and platinum. Thus this paper focuses on the development of a selective method that enables Pd(II) determination in the presence of Pt(IV) ions using the azo-dye tropaeolin OO (TR). For this purpose, the process of the metalorganic complex formation and Pd(II) ions determination were studied by using UV–Vis spectrophotometry under different conditions: solvents (water and B-R buffer), pH (2.09–6.09), temperature (20–60 °C), anions and cations concentrations. The formed metalorganic complex between Pd and tropaeolin OO allows for distinguishing Pd(II) ions from both platinum complexes, i.e. Pt(II), Pt(IV). Moreover, the proposed method can be applied to solutions containing both chloride and chlorate ions. The obtained characteristic spectrum with two maxima allows the determination of palladium even in the presence of other cations (Na, K, Mg, Zn, Co, Ni, Al) and changed concentrations of Pt(IV) ions. Furthermore, the developed spectrophotometric method for the Pd(II) ions determination using tropaeolin OO is characterized by high selectivity towards palladium ions. 相似文献
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ukasz Pecio Asmaa M. Otify Fatema R. Saber Yasser A. El-Amier Moataz Essam Shalaby Solomiia Kozachok Amira K. Elmotayam ukasz
witek Adrianna Skiba Krystyna Skalicka-Wo
niak 《Molecules (Basel, Switzerland)》2022,27(21)
Iphiona mucronata (Family Asteraceae) is widely distributed in the Eastern desert of Egypt. It is a promising plant material for phytochemical analysis and pharmacologic studies, and so far, its specific metabolites and biological activity have not yet been thoroughly investigated. Herein, we report on the detailed phytochemical study using UPLC-Q-TOF-MS approach. This analysis allowed the putative annotation of 48 metabolites belonging to various phytochemical classes, including mostly sesquiterpenes, flavonoids, and phenolic acids. Further, zebrafish embryotoxicity has been carried out, where 100 µg/mL extract incubated for 72 h resulted in a slow touch response of the 10 examined larvae, which might be taken as a sign of a disturbed peripheral nervous system. Results of in vitro testing indicate moderate cytotoxicity towards VERO, FaDu, and HeLa cells with CC50 values between 91.6 and 101.7 µg/mL. However, selective antineoplastic activity in RKO cells with CC50 of 54.5 µg/mL was observed. To the best of our knowledge, this is the first comprehensive profile of I. mucronata secondary metabolites that provides chemical-based evidence for its biological effects. A further investigation should be carried out to precisely define the underlying mechanisms of toxicity. 相似文献
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Teobald Kupka Adrianna Mnich Małgorzata A. Broda 《Magnetic resonance in chemistry : MRC》2019,57(8):489-498
Nuclear shieldings and chemical shifts of 5-fluorocytosine (5FC) were predicted in the gas phase and DMSO solution modeled by polarizable continuum model using B3LYP density functional and revised STO(1M)-3G basis set. For comparison, eight arbitrary selected basis sets including STO-3G and medium-size Pople-type and larger dedicated Jensen-type ones were applied. The former basis sets were significantly smaller, but the calculated structural parameters, harmonic vibrational frequencies, were very accurate and close to those obtained with larger, polarization-consistent ones. The predicted 13C and 1H chemical shieldings of 5FC and cytosine, selected as parent molecule, were acceptable (root mean square for 13C chemical shifts in DMSO of about 5 ppm and less) though less accurate than those calculated with large basis sets, dedicated for prediction of nuclear magnetic resonance parameters. 相似文献
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Górniak Agata Czapor-Irzabek Hanna Złocińska Adrianna Karolewicz Bożena 《Journal of Thermal Analysis and Calorimetry》2021,144(4):1219-1227
Journal of Thermal Analysis and Calorimetry - The objective of this work was to investigate binary pharmaceutical mixtures of ezetimibe (EZT) and aspirin (ASA) in order to identify whether the... 相似文献
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Natalia Festinger Adrianna Lemiesz Ewelina Skowron Sylwia Smarzewska Witold Ciesielski 《Electroanalysis》2021,33(4):854-863
A sensitive square-wave voltammetry (SWV) method based on basal-plane pyrolytic graphite electrode (BPPGE) and edge-plane pyrolytic graphite electrode (EPPGE) was developed to determine the concentration of the pesticide mandipropamid (MAN) in spiked river water and grape juice samples. Under optimal experimental conditions, the SWV response of EPPGE and BPPGE was linear over the concentration ranges of 0.7 to 9.0 μmol L−1 and 0.5 to 10.0 μmol L−1, respectively. The method was successfully used to determine MAN in spiked samples with good recovery. Cyclic voltammetry (CV) was conducted to understand the mechanism underlying the electrode process of MAN. 相似文献
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