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R. H. Adie T. B. Wood und W. A. Drushel 《Fresenius' Journal of Analytical Chemistry》1909,48(1):53-55
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E. Cohen J. W. Commelin Pfeffer van 't Hoff Ladenburg Adie Tammann Raoult Naccari Ponsot H. N. Morse D. W. Horn J. C. W. Frazer B. S. Hopkins E. J. Hoffmann W. L. Kennon L. F. Lovelace W. W. Holland F. M. Rogers P. B. Dunbar B. Mears B. F. Lovelace Berkeley Hartley Barlow und L. Kahlenberg 《Fresenius' Journal of Analytical Chemistry》1909,48(4-5):273-278
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Michael E. Cooper Susan Gregory Elaine Adie Sian Kalinka 《Journal of fluorescence》2002,12(3-4):425-429
A series of functionalized, water-soluble, pH-sensitive pentamethine cyanine (CyTM5) dyes has been designed and synthesized. These probes are fluorescent in acidic media but are non-fluorescent in an alkaline environment. Subtle changes to the structure of these probes can lead to pronounced changes in the pKa of these probes. These probes have been utilized in a cellular environment to detect localized changes in pH using the IN Cell Analyzer, a confocal imager formatted for imaging of cell-based assays. 相似文献
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We present theoretical calculations, based on a random phasor sum model, which show that the optical coherence tomography speckle contrast ratio is dependent on the local density of scattering particles in a sample, provided that the effective number of scatterers in the probed volume is less than about five. We confirm these theoretical predictions experimentally, using suspensions of microspheres in water. The observed contrast ratios vary in value from the Rayleigh limit of 0.52 to in excess of 2, suggesting that the contrast ratio could be useful in optical coherence tomography, particularly when imaging in ultrahigh-resolution regimes. 相似文献
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Zysk AM Adie SG Armstrong JJ Leigh MS Paduch A Sampson DD Nguyen FT Boppart SA 《Optics letters》2007,32(4):385-387
We present a novel needle-based device for the measurement of refractive index and scattering using low-coherence interferometry. Coupled to the sample arm of an optical coherence tomography system, the device detects the scattering response of, and optical path length through, a sample residing in a fixed-width channel. We report use of the device to make near-infrared measurements of tissues and materials with known optical properties. The device could be used to exploit the refractive index variations of tissue for medical and biological diagnostics accessible by needle insertion. 相似文献
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