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编写培养学生实践能力的实验教材 总被引:2,自引:0,他引:2
以英国Loughborough技术大学物理系实验教材中的自由下落实验为例,提出如何编写培养学生实践能力的实验教材应引起思考。 相似文献
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Dual mechanisms of Bcl-2 regulation in IP3-receptor-mediated Ca2+ release: A computational study
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Inositol 1,4,5-trisphosphate receptors (IP3R)-mediated calcium ion (Ca2+) release plays a central role in the regulation of cell survival and death. Bcl-2 limits the Ca2+ release function of the IP3R through a direct or indirect mechanism. However, the two mechanisms are overwhelmingly complex and not completely understood. Here, we convert the mechanisms into a set of ordinary differential equations. We firstly simulate the time evolution of Ca2+ concentration under two different levels of Bcl-2 for the direct and indirect mechanism models and compare them with experimental results available in the literature. Secondly, we employ one- and two-parameter bifurcation analysis to demonstrate that Bcl-2 can suppress Ca2+ signal from a global point of view both in the direct and indirect mechanism models. We then use mathematical analysis to clarify that the indirect mechanism is more efficient than the direct mechanism in repressing Ca2+ signal. Lastly, we predict that the two mechanisms restrict Ca2+ signal synergistically. Together, our study provides theoretical insights into Bcl-2 regulation in IP3R-mediated Ca2+ release, which may be instrumental for the successful development of therapies to target Bcl-2 for cancer treatment. 相似文献
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用熔地合成了三元CeFe4Al8化合物,并用X射线粉末衍射法测定了它的结构。在77-302K测定了它的磁化率,在室温下测量了它的穆斯堡尔谱。结果表明,这种化合物的磁服从居里-外斯定律,其奈耳温度为127K,有效磁子数为6.97。铁原子的平均有效磁子数为1.21。 相似文献
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光速测量的发展 总被引:1,自引:0,他引:1
光速是经典物理学中的一个重要的基本恒量.它的数值的测定及其特性的研究与近代物理学和实验技术的许多重大问题关系密切,并在现代计量科学的发展中占有重要地位,因此它一直受到物理学家们的广泛注意.1983年召开的第十七次国际计量大会正式通过了和光速直接有关的“米” 的新定义:“米是光在真空中在(1/299792458)s的时间间隔内所进行的路程的长度”.由此更可显示光速的重要意义. 一、历史的回顾 光的传播速度问题,在古代是有很大争论的.虽然早在公元前一百年就有人提出了光速的有限性[1],但在1676年以前人们一直认为是瞬时传播的.1607年,伽… 相似文献
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