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Shuang LIANG Xue-lai WANG Ming-yang ZOU Han WANG Xue ZHOU Cai-hong SUN Wei XIA Li-jie Wu TakashiX.FUJISAWA Akemi TOMODA 《浙江大学学报(自然科学英文版)》2014,(3):264-271
Objective: A study in a Caucasian population has identified two single-nucleotide polymorphisms (SNPs) in ZNF533, one in DOCK4, and two in IMMP2L, which were all significantly associated with autism. They are located in AUTS1 and AUTS5, which have been identified as autism susceptibility loci in several genome-wide screens. The present study aimed to investigate whether ZNF533, DOCK4, and IMMP2L genes are also associated with autism in a northeastern Chinese Han population. Methods: We performed a similar association study using families with three individuals (one autistic child and two unaffected parents). A family-based transmission disequilibrium test (TDT) was used to analyze the results. Results: There were significant associations between autism and the two SNPs of ZNF533 gene (rs11885327: X^2=4.5200, P=0.0335; rs1964081 :)(2=4.2610, P=0.0390) and the SNP of DOCK4 gene (rs2217262 X^2=5.3430, P=0.0208). Conclusions: Our data suggest that ZNF533 and DOCK4 genes are linked to a predisposition to autism in the northeastern Chinese Han population. 相似文献
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Spin and pseudospin symmetries of the Dirac equation with shifted Hulthén potential using supersymmetric quantum mechanics
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Akpan N.Ikot Elham Maghsoodi Eno J. Ibanga Saber Zarrinkamar Hassan Hassanabadi 《中国物理 B》2013,(12):74-81
In this paper, we obtain approximate analytical solutions of the Dirac equation for the shifted Hulthén potential within the framework of spin and pseudospin symmetry limits for arbitrary spin–orbit quantum number κ using the supersymmetry quantum mechanics. The energy eigenvalues and the corresponding Dirac wave functions are obtained in closed forms. 相似文献
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