TRAIL与kallistatin联合表达载体的构建及抗肿瘤活性分析

为研究肿瘤坏死因子相关凋亡诱导配体(TRAIL)与组织激肽释放酶结合蛋白(kallistatin)联合用药的抗肿瘤作用,构建TRAIL与kallistatin双表达的重组质粒pAM-CAG-Kal-IRES-TRAIL,将重组质粒转染A549,LO-2,NCI-H446和Hela细胞,考察其抗肿瘤活性.实验结果表明:构建的双表达载体能同时表达TRAIL与kallistatin,且均能分泌至培养基中;TRAIL与kallistatin联合表达对肿瘤细胞活力的抑制作用明显增强,诱导肿瘤凋亡的作用也明显增强,说明联合表达TRAIL与kallistatin能够增强抗肿瘤活性.     

浅谈班级管理模式

借鉴企业管理模式,在班级管理中,以班主任为核心,通过建立一支有战斗力的班、团干部队伍,协助班主任完成班级管理的战略目标,以带好本班这支队伍。     

Isoscaling of the Fission Fragments with Langevin Equation

The Langevin equation is used to simulate the fission process of ^112Sn ^112Sn and ^116Sn ^116Sn. The mass distribution of the fission fragments are given by assuming the process of symmetric fission or asymmetric fission with the Gaussian probability sampling. The isoscaling behaviour has been observed from the analysis of fission fragments of both the reactions, and the isoscaling parameter α seems to be sensitive to the width of fission probability and the beam energy.     

A Quasi-Symmetric Coupled Quantum Well and Its Electric-Optical Properties

We propose a novel coupled quantum well structure, i.e. a quasi-symmetric coupled quantum well (QSCQW). Based on the demands of optical switching devices for quantum well materials, the QSCQW configuration is further optimized. Consequently, in the case of low applied electric field 25kV/cm and low absorption loss 100cm^-1, a large field-induced refractive index change (for TE mode, n = 0.0106; for TM mode, n = 0.0115) is obtained in the QSCQW structure at the operation wavelength 1550hm. The value is in one or two order of magnitude larger than that in a rectangular quantum well and about 50% larger than that of five-step asymmetric coupled quantum well structure under the same working conditions. The refractive index change obtained with the optimized QSCQW under so low absorption loss and applied electric field is very attractive for semiconductor optical switching devices. This manifests that the QSCQW structure has a great potential for applications in ultra-fast and low-voltage optical switches and in travelling wave modulators.     

Spin Squeezing and Entanglement of Many-Particle Spin-Half States

In many-particle spin-half systems with exchange symmetry, we find that the spin squeezing is related to two types of entanglement, the bipartite and the pairwise entanglement. A quantitative relationship is revealed for the spin squeezing parameter, the tangle, and the concurrence. We find that a class of states is spin squeezed if the pairwise entanglement is stronger than the bipartite entanglement.     

水泥混凝土路面破损原因及其修复方案研究

本文分析研究了旧水泥混凝土路面破损的产生原因,提出了几种可供选择的修复方案,提出采用钢纤维混凝土路面加铺层做修复罩面,并介绍了加铺钢纤维混凝土路面的施工要点。     

ebXML消息服务规范的互操作性测评研究

主要研究如何对电子商务平台的互操作性进行测评，介绍了互操作性基本概念，描述了基于ebXML规范的互操作性测评体系，最后通过ebXML消息服务互操作性测试，验证了测试模型，步骤和评价标准的正确性与有效性．     

增强应用意识 培养建模能力

中国科学院数学物理部在《今日数学及其应用》一文中阐明了对数学应用的新认识：“国家的繁荣富强，关键在于高新的科技和高效率的经济管理，高新技术的基础科学是应用科学，而应用科学的基础是数学．”可以说数学的广泛应用已被视为科技进步的重要标志．高中数学教学目标已明确要求学生“逐步学会把实际问题归结为数学模型，然后运用数学方法进行探索、猜测、判断、证明、运算、检验，使问题得到解决．”这不仅符合于数学本身发展的需要，也是社会发展的需要，是培养适应当今以高科技为主旋律的人才的需要．所以在数学教学中，加强对数学应…     

N_2和O_2纯转动拉曼光谱(PRRS)的温度特性

计算了N2 和O2 的PRRS ,讨论了其温度特性。提出通过测量N2 和O2 的PRRS计算大气温度的方法。