认知角度下同义反复话语的阐释

逻辑学家、修辞学家、语言学家等都对有关同义反复话语的解读提出了各自的观点,但还存在一些问题。本文从认知语言学的角度,运用转喻理论对同义反复话语进行阐释,力求找寻一种更好的方法。     

高校发展新常态下学生档案管理柔性化研究

在介绍柔性管理理论的内涵及特征的基础上,从3个“有利于”的角度阐述了高校学生档案管理柔性化的必要性,提出了高校学生档案管理应遵循的以生为本原则、前瞻性原则及真实完整原则,并从创新档案储存内容、发挥档案育人功能、提高档案人员素质3个方面探索了档案管理柔性化的实现途径.     

激光显微共聚焦拉曼光谱仪变温系统的设计与研制

针对常规激光显微共聚焦拉曼光谱仪无法满足物质变温,特别是低温测试需求的问题,设计了适用于拉曼光谱仪的高精度变温系统。该系统采用GM制冷机作为制冷源,利用高纯无氧铜作为导冷介质,通过将GM制冷机的冷量传导至样品台,并利用控温仪进行温度控制,可以实现待测样品10 K-402 K范围的温度变化控制,控温精度高于0.008 K。相比于常规的低温测试设备,该系统无需采用液氮、液氦进行制冷,大幅降低了设备的使用及维护费用。同时,使用激光显微共聚焦拉曼光谱仪搭载该系统,成功获得了Si、V₂O₅等材料的变温拉曼光谱,验证了激光显微共聚焦拉曼光谱仪变温系统设计的可靠性。     

大学新生适应性问卷在西部大学新生人群中的应用分析

采用大学新生适应性问卷对960名西部地区大学新生进行施测,考察该问卷在西部大学新生中的应用情况。结果表明:除个别题目外,几乎所有题目的区分度均达到可接受水平;问卷的分半信度,α系数,β系数,r系数和组合信度等信度指标均达到较好水平;验证性因素分析显示模型的各项拟合指标均达到可接受水平。大学新生适应性问卷的个别题目稍加修改后很适合应用于西部大学新生群体。     

网球运动竞技能力专项特征研究

通过文献资料法、特征解析法和访谈法等研究方法,系统地分析了竞技网球运动的专项特征,网球技战术特征、体能特征及心智特征,对揭示网球专项运动的运动规律,提高认识,增强了解等都具有重要意义,同时对提高网球运动的专项训练水平也可以提供科学依据。     

Controllable Assembly and Properties of Brain Targeting Peptides with Tetrahedral Framework Nucleic Acids北大核心CSCD

In this study,the armed tetrahedral DNA nanostructures（TDN）are designed to bind single or three complementary strands of armed chain（1-ANG-TDN,3-ANG-TDN）which is modified with angiopep-2 or other brain targeting peptides（TAT,TGN）. We compare the cell viability and cellular uptake of 1-ANG-TDN or 3-ANG-TDN in brain capillary endothelial（bEnd. 3）cells and Uppsala 87 malignant glioma（U87） cells. In addition,the cell viability and cellular uptake of ANG-TDN,TAT-TDN and TGN-TDN in bEnd. 3 cells are investigated respectively. The results show that these probes are not cytotoxic to bEnd. 3 cells and U87 cells at concentrationsbelow 100 nmol/L. After being incubated with bEnd. 3cells for 0. 5 h,the cellular uptake of 3-ANG-TDN is higher than that of 1-ANG-TDN（P<0. 01）. After being incubated with U87 cells for 1h,the cellular uptake of 3-ANG-TDN is higher than that of 1-ANG-TDN（P<0. 01）. After 2 h,there is no obvious difference in cellular uptake between 1-ANG-TDN and 3-ANG-TDN. ANG-TDN,TAT-TDN and TGN-TDN are up-taken by bEnd. 3 cells much more than TDN（P<0. 01）. However,there isno statistical difference among ANG-TDN,TAT-TDN and TGN-TDN（P>0. 05）. These results indicate that the targeting of ANG-TDN probe can be improved by increasing the number of peptides or prolonging the co-incubation time. This discovery providesareference for the multifunctional modification of tetrahedral framework nucleic acid. When a single peptidelinked with TDN achieves the brain targeting,other sites of TDN can be modified by other functional groups to expand the structure and function. Tetrahedral framework nucleic acids can be used not only as an assembly platform for ANG peptides,but also for the assembly of other brain-targeting peptides （TAT and TGN）to design brain-targeting probes. © 2022, Science Press (China). All rights reserved.     

废弃铜尾矿水泥熟料的制备及性能表征

研究了废弃铜尾矿部分替代黏土和石灰石等原料,混合煅烧制备水泥熟料.通过对熟料f-CaO含量的测定,对熟料进行岩相、XRD、SEM分析,对熟料的抗压强度及固化重金属进行测定.研究了铜尾矿掺入对熟料易烧性、熟料矿物组成、熟料抗压强度和水化产物的影响,探讨了铜尾矿熟料的固化重金属性能.结果表明:铜尾矿部分取代黏土作为硅质原料...