Synthesis,Photo-physical Properties and Cell Imaging of Meso-2,6-dichlorophenyl Boron-dipyrromethene Derivatives

The meso-2,6-dichlorophenyl boron-dipyrromethene(BODIPY) derivative 1 was synthesized and characterized by single-crystal X-ray diffraction analysis, 1 H NMR and Esi-HRMS. Compound 1 crystallizes in monoclinic, space group P21/n with a = 8.717(4), b = 20.938(9), c = 12.402(6) ?, β = 98.660(7)°, V = 2237.7(17) ?3, D3 c = 1.333 Mg/cm, F(000) = 936, μ = 0.319 –mm1, Z = 4, the final R = 0.0537 and wR = 0.1556 for 5064 observed reflections with I 2ζ(I). Its photophysical properties were investigated by fluorescence and UV-Vis spectrum. 1 shows high fluorescence quantum yield in different solvents and poor solvent effect. In addition, compound 1 has high values of initial decomposition temperature(298 ℃). Moreover, cell imaging experiments showed 1 is promising for further bioimaging applications.     

C颗粒对Cp /AZ91D复合材料铸态显微组织的影响

通过复合铸造工艺制备了C_p/AZ91D复合材料，研究了C颗粒含量和保温时间等参数对该复合材料显微组织和力学性能的影响。结果表明，与保温时间相比，C_p的晶粒细化作用更为显著。当添加C_p质量分数为1.5%，保温时间15 min时，C_p/AZ91D复合材料铸锭平均晶粒尺寸由176 μm降低至32 μm，组织整体细化均匀，增强相C颗粒在复合材料基体中均匀分布，并且硬度值最高，达到89.07 HV。     

In Vitro Biossay for Assessing Estrogenic Activity of Sewage Treatment Works

The estrogenic activity of influents and effluents of five municipal sewage treatment works(STWs)in Nanjing was investigated.The water samples were enriched by solid phase extraction,then eluted with different polar solvents,and finally three fractionated extracts were obtained.Estrogen receptor recombinant yeast screen was used to evaluate the estrogenic activity of individual fractionated extracts and their mixture.The results show that the influents and effluents of the two STWs mainly receiving industri...     

基于苯并咪唑衍生物的“关-开”型连续性荧光探针

以胺甲基苯并咪唑和水杨醛为原料设计合成了一个苯并咪唑衍生物荧光探针,通过荧光分光光度法和紫外分光光度法探寻其对常见阴阳离子的选择性识别性能。研究结果表明,Cu2 对合成得到的苯并咪唑衍生物具有荧光猝灭-“关”的作用,而S2O72-对该荧光猝灭体系具有荧光恢复-“开”的作用。据此,提出了具有实现对Cu2 、S2O72-的荧光“关-开”型探针。     

溃坝生命损失评估模型研究

鉴于溃坝生命损失评估的复杂性,借鉴国内外生命损失评估的相关研究成果,研究溃坝时警报与撤离过程,建立了评估暴露人口数量的警报与撤离模型以及死亡率评估模型;基于我国历史溃坝调查资料,提出以溃坝洪水特征为依据的淹没范围分区思想,建立了淹没区划标准及相应死亡率函数,提出适用于我国的溃坝生命损失评估方法及估算公式。实例应用表明,该方法及估算公式能比较客观地评估我国的溃坝生命损失情况。     

牛顿环实验方法的改进

利用指导大学生创新活动计划项目,自主搭建了数字化等厚干涉观测系统,包括计算机,CCD摄像头和透镜组件等装置和一套自行研发等厚干涉数据采集和处理软件,对大学物理实验中的牛顿环实验方法进行了改进,为精确观测牛顿环实验现象提供了一种有效的观测系统和数据处理方法。     

苯并咪唑衍生物的“关-开”型连续性荧光探针检测Cu2+和S2O72-

以胺甲基苯并咪唑和水杨醛为原料设计合成了一个苯并咪唑衍生物荧光探针,通过荧光分光光度法和紫外分光光度法探寻其对常见阴阳离子的选择性识别性能。研究结果表明,Cu2+对合成得到的苯并咪唑衍生物具有荧光猝灭——"关"的作用,而S2O72-对该荧光猝灭体系具有荧光恢复——"开"的作用。据此,提出了具有实现对Cu2+,S2O72-的荧光"关-开"型探针.