氨曲南中间体的合成工艺

以L-苏氨酸为原料,采用"一锅法",经酯化、氨解、氨基保护和甲磺酰化直接制得合成氨曲南主环的重要中间体N-Cbz-O-甲磺酰基-L-苏氨酰胺;采用甲基磺酰氯进行磺酰化反应,以DMAP-吡啶作复合催化剂可减少副反应发生。改进后的工艺使反应收率高达85.0%。     

Growth and transport properties of topological insulator Bi_2Se_3 thin film on a ferromagnetic insulating substrate

Exchange coupling between topological insulator and ferromagnetic insulator through proximity effect is strongly attractive for both fundamental physics and technological applications. Here we report a comprehensive investigation on the growth behaviors of prototype topological insulator Bi_2Se_3 thin film on a single-crystalline LaCoO_3 thin film on SrTiO_3 substrate, which is a strain-induced ferromagnetic insulator. Different from the growth on other substrates, the Bi_2Se_3 films with highest quality on LaCoO_3 favor a relatively low substrate temperature during growth. As a result, an inverse dependence of carrier mobility with the substrate temperature is found. Moreover, the magnetoresistance and coherence length of weak antilocalization also have a similar inverse dependence with the substrate temperature, as revealed by the magnetotransport measurements. Our experiments elucidate the special behaviors in Bi_2Se_3/LaCoO_3 heterostructures,which provide a good platform for exploring related novel quantum phenomena, and are inspiring for device applications.     

头孢唑兰活性酯合成工艺改进

在混合溶剂条件下,以亚磷酸三乙酯替代三苯基磷做缩合催化剂,改进头孢唑兰活性酯的合成工艺。经正交实验,考察溶剂、温度和时间等因素对活性酯收率和质量的影响,确定最佳工艺条件为:n(氨噻二唑肟乙酸)∶n(二硫化二苯并噻唑)∶n(亚磷酸三乙酯)=1∶1.1∶1.2,V(二氯甲烷)∶V(乙腈)=1∶1,反应温度为25℃,反应时间4 h。在此条件下,产品收率可达94.8%,HPLC测定纯度为99.2%。     

1 000 MPa级双相钢薄板极限成形性能

基于圆筒拉深试验,获得了1 000 MPa级先进高强度钢拉深时破裂的临界点和极限拉延比(LDR).研究了Hill、Barlat和BBC 3种不同屈服准则的数值仿真效果.结果表明：1 000 MPa级双相钢LDR值为2.07,且Barlat屈服准则模拟结果与实际试验相符.对断口进行扫锚电镜（SEM）观测,发现1 000 MPa级双相钢有别于传统板材,其拉深断裂模式为沿板材厚向45°的韧性切向断裂,无明显颈缩现象.     

Electron localization in ultrathin films of three-dimensional topological insulators

The recent discovery of three-dimensional(3D) topological insulators(TIs) has provided a fertile ground for obtaining further insights into electron localization in condensed matter systems.In the past few years,a tremendous amount of research effort has been devoted to investigate electron transport properties of 3D TIs and their low dimensional structures in a wide range of disorder strength,covering transport regimes from weak antilocalization to strong localization.The knowledge gained from these studies not only offers sensitive means to probe the surface states of 3D TIs but also forms a basis for exploring novel topological phases.In this article,we briefly review the main experimental progress in the study of the localization in 3D TIs,with a focus on the latest results on ultrathin TI films.Some new transport data will also be presented in order to complement those reported previously in the literature.     

沥青路面预防性养护的行驶质量评价

随着国民经济的快速发展,人们对公路路面行驶质量的快速、舒适、安全和经济等方面提出了更高的要求。预防性养护可以保持路面良好的服务水平,降低养护成本,延长路面使用寿命。结合预防性养护的适用条件,探讨高速公路沥青路面行驶质量的评价标准,以合理评价运营中路面的行驶质量,为预防性养护时机提供依据,具有重要的意义。