通过进化模块审视拟南芥尿苷二磷酸葡糖基转移酶功能多样性

属于糖基转移酶(GTs)家族1的尿苷二磷酸(UDP)-糖基转移酶(UGT)在转移拟南芥中的糖基的转移和糖基化次级代谢物中起重要作用.重建的系统发育树对这个多基因家族的进化关系和功能提供了新的见解和研究.通过综合分析系统发育谱和重建的系统发育树,我们系统地分析了112个拟南芥UGTs.在我们的工作中,我们检测到五个不同的进化保守模块,大多数UGTs分为同一模块,表明拟南芥UGTs在进化过程中是相当保守的.接下来收集拟南芥UGT的底物,并将它们映射到直向同源组,揭示UGT在结合特异性底物中的进化关系.通过扫描271不同物种,还预测一些未报告的蛋白质与拟南芥UGTs密切相关.     

季铵盐型阳离子表面活性剂与牛血清白蛋白的相互作用

本文合成并表征了三种不同烷基链长度的季铵盐型阳离子表面活性剂：N-十二烷基-N-（2-羟乙基）-N,N-二甲基溴化铵（DHDAB）、N-十四烷基-N-（2-羟乙基）-N,N-二甲基溴化铵（THDAB）、N-十六烷基-N-（2-羟乙基）-N,N-二甲基溴化铵（CHDAB）。采用荧光光谱法、紫外-可见光谱法、动态光散射法和等温滴定量热法对三种表面活性剂与牛血清白蛋白（BSA）的相互作用进行研究。荧光光谱研究表明,三种表面活性剂主要与BSA分子内的色氨酸残基发生相互作用,导致蛋白质的构象发生变化,且表面活性剂烷基链越长,与BSA的相互作用就越强。BSA荧光猝灭的主要原因是静态猝灭,紫外光谱实验同样验证了静态猝灭的存在。等温滴定量热法结果表明低浓度的表面活性剂与BSA主要发生静电作用和疏水作用而放热。动态光散射结果表明高浓度的表面活性剂会使BSA结构被破坏。本文揭示了表面活性剂与BSA相互作用的机理,为表面活性剂的广泛应用提供了理论基础。     

Coherence migration in high-dimensional bipartite systems

The conservation law for first-order coherence and mutual correlation of a bipartite qubit state was firstly proposed by Svozilík et al., and their theories laid the foundation for the study of coherence migration under unitary transformations. In this paper, we generalize the framework of first-order coherence and mutual correlation to an arbitrary (m $\otimes$ n)-dimensional bipartite composite state by introducing an extended Bloch decomposition form of the state. We also generalize two kinds of unitary operators in high-dimensional systems, which can bring about coherence migration and help to obtain the maximum or minimum first-order coherence. Meanwhile, the coherence migration in open quantum systems is investigated. We take depolarizing channels as examples and establish that the reduced first-order coherence of the principal system over time is completely transformed into mutual correlation of the (2 $\otimes$ 4)-dimensional system-environment bipartite composite state. It is expected that our results may provide a valuable idea or method for controlling the quantum resource such as coherence and quantum correlations.