A least mean square error synthesis with pattern constraints atmultiple frequencies

The pattern synthesis techinque described allows the power pattern to be optimized in a very useful sense over the desired operating band of the antenna array. This is an improvement over previous techniques involving constraints on such artificial parameters as source norm and superdirectivity ratio, which do not, in fact, ensure a useful pattern bandwidth. The procedure described provides minimum mean square error over an arbitrary number of discrete frequencies     

Tumor detection in nonstationary backgrounds

The authors introduce two detectors which they use to locate simulated tumors of fixed size in clinical gamma-ray images. The first method was conceived when it was observed that small tumors possess an identifiable signature in curvature feature space, where "curvature" is the local curvature of the image data when viewed as a relief map. Computed curvature values are mapped to a normalized significance space using a windowed statistic. The resulting test statistic is thresholded at a chosen level of significance to give a positive detection. Nonuniform anatomic background activity is effectively suppressed. The second detector is an adaptive prewhitening matched filter, which uses a form of preprocessing known as statistical scaling to adaptively prewhiten the background. Tests are performed using simulated Gaussian-shaped tumors superimposed on twelve clinical gamma ray images. When the tumors to be detected are small-less than 3 pixels in diameter-the curvature detector out-performs the matched filter in true positive/false positive tests. A mean true positive rate of 95% at one false positive per image is achieved when the local signal-to-noise ratio of the tumor-background is >/=2. At larger tumor sizes the best performance is displayed by a different form of matched filter, namely the statistical correlation function proposed by Pratt (1991).     

Wavelet transforms for detecting microcalcifications in mammograms

Clusters of fine, granular microcalcifications in mammograms may be an early sign of disease. Individual grains are difficult to detect and segment due to size and shape variability and because the background mammogram texture is typically inhomogeneous. The authors develop a 2-stage method based on wavelet transforms for detecting and segmenting calcifications. The first stage is based on an undecimated wavelet transform, which is simply the conventional filter bank implementation without downsampling, so that the low-low (LL), low-high (LH), high-low (HL), and high-high (HH) sub-bands remain at full size. Detection takes place in HH and the combination LH+HL. Four octaves are computed with 2 inter-octave voices for finer scale resolution. By appropriate selection of the wavelet basis the detection of microcalcifications in the relevant size range can be nearly optimized. In fact, the filters which transform the input image into HH and LH+HL are closely related to prewhitening matched filters for detecting Gaussian objects (idealized microcalcifications) in 2 common forms of Markov (background) noise. The second stage is designed to overcome the limitations of the simplistic Gaussian assumption and provides an accurate segmentation of calcification boundaries. Detected pixel sites in HH and LH+HL are dilated then weighted before computing the inverse wavelet transform. Individual microcalcifications are greatly enhanced in the output image, to the point where straightforward thresholding can be applied to segment them. FROG curves are computed from tests using a freely distributed database of digitized mammograms.     

Circular cross-polarization measurements on earth-space paths at 11,7 GHz

Rain and icecrystal depolarization measurements were made on earthspace paths at four locations across Canada using the circularlypolarized 11.7 GHz beacon transmission from the cts satellite. Results show that when rain is the dominant depolarization mechanism, crosspolarization discrimination (xpd)is statistically related to copolar attenuation (cpa)according to xpd =U?20 log cpa with U showing improvement with increasing elevation angle. Icecrystal depolarization events, with accompanying differential phase shifts as large as 20°, were also observed. An analysis separating these events from the data demonstrates that at 11.7 GHz icecrystal depolarization degrades xpd statistics by less than 1 dB at the small percentages of time.     

Inhibition of UV-induced immune suppression and interleukin-10 production by plant oligosaccharides and polysaccharides

Application of Aloe barbadensis poly/oligosaccharides to UV-irradiated skin prevents photosuppression of delayed-type hypersensitivity (DTH) responses in mice. We tested the hypothesis that these carbohydrates belong to a family of biologically active, plant-derived polysaccharides that can regulate responses to injury in animal tissues. C3H mice were exposed to 5 kJ/m2 UVB from unfiltered FS40 sunlamps and treated with between 1 pg and 10 micrograms tamarind xyloglucans or control polysaccharides methylcellulose or dextran in saline. The mice were sensitized 3 days later with Candida albicans. Tamarind xyloglucans and purified Aloe poly/oligosaccharides prevented suppression of DTH responses in vivo and reduced the amount of interleukin (IL)-10 observed in UV-irradiated murine epidermis. Tamarind xyloglucans were immunoprotective at low picogram doses. In contrast, the control polysaccharides methylcellulose and dextran had no effect on immune suppression or cutaneous IL-10 at any dose. Tamarind xyloglucans and Aloe poly/oligosaccharides also prevented suppression of immune responses to alloantigen in mice exposed to 30 kJ/m2 UVB radiation. To assess the effect of the carbohydrates on keratinocytes, murine Pam212 cells were exposed to 300 J/m2 UVB radiation and treated for 1 h with tamarind xyloglucans or Aloe poly/oligosaccharides. Treatment of keratinocytes with immunoprotective carbohydrates reduced IL-10 production by approximately 50% compared with the cells treated with UV radiation alone and completely blocked suppressive activity of the culture supernatants in vivo. The tamarind xyloglucans also blocked UV-activated phosphorylation of SAPK/JNK protein but had no effect on p38 phosphorylation. These results indicate that animals, like plants, may use carbohydrates to regulate responses to environmental stimuli.     

Symbol synchronization using signal samples and interpolation

A method for symbol synchronization using two unsynchronized signal samples per symbol is presented. Signal values between the sample points are calculated by interpolation and then processed digitally to find a suitable strobe point. The interpolated value at the strobe point is used for data detection or input to an equalizer. Simulations show that low variance timing estimates can be made for pulses with raised-cosine spectra degraded by quadratic delay distortion     

The Interaction of Benzyl Alcohol with Trimethoxyboroxine : Amine Adducts of Triarylboroxines as Model Compounds

The interaction of benzyl alcohol with trimethoxyboroxine has been investigated by hydrogen-1 and carbon-13 NMR and IR spectroscopy. These techniques indicate formation of a weak Lewis acid/base adduct, additionally stabilized by a hydrogen-bonding interaction, which undergoes rapid ligand exchange at room temperature. The system has been modelled by the synthesis and characterization of a series of amine-triarylboroxine adducts. These adducts rapidly undergo ligand dissociation-recombination in solution with ΔG⁺ of ca. 40-50 kJ/mol.     

Mid-infrared pulses generated from the mixing output of an amplified, dual-wavelength Ti:sapphire system

We demonstrate the generation of femtosecond mid-infrared pulses by direct difference-frequency mixing in a AgGaS(2) crystal of two intense pulses from a dual-wavelength oscillator that have been simultaneously amplified in a single regenerative amplifier. A pulse energy of as much as 1.6 muJ was achieved at wavelengths of 9-11 mum.     

Angularly correlated two-electron repulsion operators

The Bohr model for two-electron atoms is modified to include angular correlation effects in an empirical fashion. An extension of the model to two-centers is given. Simple expressions for one- and two-center Coulomb repulsion integrals are derived and compared with semi-empirical approximations.

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Zusammenfassung Die Bohrsche Modellvorstellung für ein Atom mit zwei Elektronen wird so modifiziert, daß die Winkelkorrelation empirisch berücksichtigt wird. Die Erweiterung dieses Modells auf zwei Zentren wird angegeben. Einfache Ausdrücke für Ein- und Zweizentren-Coulombintegrale werden abgeleitet und mit semiempirischen Näherungen verglichen.

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Based on a thesis submitted by RWS to the State University of New York at Albany in partial fulfillment of the requirements for the degree of Ph. D.     

Statistics of differential rain attenuation on adjacent earth-space propagation paths

Forty hours of observations of the three-dimensional radar reflectivity structure of rain in the Montreal area were used to simulate the centimetre-wavelength attenuations occurring simultaneously over a multitude of earth-space propagation paths. The same data base had been used in a previous study which confirmed that the radar estimates of attenuation statistics are in good agreement with attenuation distributions measured independently by passive radiometers. Differences between the attenuations occurring simultaneously over pairs of paths to a common point at the ground were tabulated as a function of angular path separation, viewing direction, radio frequency, and system margin. These data are required for evaluating the possibility of interference at an earth station caused by a signal from an adjacent satellite. In this study, values of angular separation from 2 to 9 degrees, radio frequencies from 11 to 30 GHz, elevation angles from 5 to 30 degrees, and system margins from 2 to 10 dB were considered. It was found that the cumulative distributions of differential attenuation could be characterized effectively by the attenuation difference occurring during 1 % of the time that the carrier signal suffered some attenuation, but not an attenuation exceeding the system margin. It was also found that this characteristic differential attenuation could be expressed to good approximation as a simple analytical function of the system parameters.