The high resolution mass spectrum of 2-acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-α-D-glucopyranose

2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-α-D-glucopyranose (I), and its analogs specifically mono (trideuterioacetylated) at O-1 (III), at N-2 (II), at O-4 (IV) and at O-6 (V), have been examined by high-resolution mass spectrometry. From the elemental compositions of the fragment ions, the mass-number shifts resulting from deuterium incorporation and analysis of metastable transitions, it has been possible to specify in detail the fragmentation pathways undergone by this molecule. The principal degradations of I proceed by initial rapid decomposition of the molecular ion (whose intensity is insignificant) by three routes: (i) by loss of the C-1 acetoxyl group as a radical to give the glycosyl cation (a), (ii) by loss of the 1-acetyl group as a radical to give an acyclic ion m/e 346 (b) and (iii) by loss of a C-6 fragment and acetic acid derived from the 3-acetate group to give m/e 241 (c).     

Tuning Aqueous Supramolecular Polymerization by an Acid-Responsive Conformational Switch

Besides their widespread use in coordination chemistry, 2,2’-bipyridines are known for their ability to undergo cis–trans conformational changes in response to metal ions and acids, which has been primarily investigated at the molecular level. However, the exploitation of such conformational switching in self-assembly has remained unexplored. In this work, the use of 2,2’-bipyridines as acid-responsive conformational switches to tune supramolecular polymerization processes has been demonstrated. To achieve this goal, we have designed a bipyridine-based linear bolaamphiphile, 1 , that forms ordered supramolecular polymers in aqueous media through cooperative aromatic and hydrophobic interactions. Interestingly, addition of acid (TFA) induces the monoprotonation of the 2,2’-bipyridine moiety, leading to a switch in the molecular conformation from a linear (trans) to a V-shaped (cis) state. This increase in molecular distortion along with electrostatic repulsions of the positively charged bipyridine-H⁺ units attenuate the aggregation tendency and induce a transformation from long fibers to shorter thinner fibers. Our findings may contribute to opening up new directions in molecular switches and stimuli-responsive supramolecular materials.     

手机电视技术和标准最新进展

手机电视目前已成为手机产业的热门话题,在相关技术日趋成熟、同时一些实验性质的试播计划获得成功的情况下,电信运营商对这项技术的兴趣也越来越高.内嵌手机电视功能的手机量产化之后预计将迅速成为电信运营商的采购重点.本文介绍了手机电视的相关技术、探讨了移动手机电视中所需的零件.     

A versatile wavelet domain noise filtration technique for medical imaging

In this paper, we propose a robust wavelet domain method for noise filtering in medical images. The proposed method adapts itself to various types of image noise as well as to the preference of the medical expert; a single parameter can be used to balance the preservation of (expert-dependent) relevant details against the degree of noise reduction. The algorithm exploits generally valid knowledge about the correlation of significant image features across the resolution scales to perform a preliminary coefficient classification. This preliminary coefficient classification is used to empirically estimate the statistical distributions of the coefficients that represent useful image features on the one hand and mainly noise on the other. The adaptation to the spatial context in the image is achieved by using a wavelet domain indicator of the local spatial activity. The proposed method is of low complexity, both in its implementation and execution time. The results demonstrate its usefulness for noise suppression in medical ultrasound and magnetic resonance imaging. In these applications, the proposed method clearly outperforms single-resolution spatially adaptive algorithms, in terms of quantitative performance measures as well as in terms of visual quality of the images.     

通过连接中心的智能无线整合将手机设计的潜力最大化

本文将探讨手机设计者可用技术的范围,以及智能IC设计如何改变无线整合的架构设计复杂性.     

High temperature superconducting transresistance amplifiers for farinfrared detectors

Far-infrared (IR) focal plane arrays are becoming increasingly important for terrestrial and space-based imaging applications. For noise reasons, it is desirable to have transresistance preamplifiers at the focal plane, and, therefore, they need to operate over wide temperature ranges. High-temperature superconducting (HTS) amplifiers that have a high gain, relatively low noise, and response times of <200 ps over at least a 10-80-K temperature range have been developed     

A continuous-time /spl Sigma//spl Delta/ ADC with increased immunity to interferers

Receivers are being digitized in a quest for flexibility. Analog filters and programmable gain stages are being exchanged for digital processing at the price of a very challenging ADC. This paper presents an alternative solution where the filter and programmable gain functionality is integrated into a /spl Sigma//spl Delta/ ADC. The novel filtering ADC is realized by adding a high-pass feedback path to a conventional /spl Sigma//spl Delta/ ADC while a compensating low-pass filter in the forward path maintains stability. As such, the ADC becomes highly immune to interferers even if they exceed the maximum allowable input level for the wanted channel. As a consequence, the ADC input range can be programmed dynamically to the level of the wanted signal only. This results in an input-referred dynamic range of 89 dB in 1-MHz bandwidth and an intentionally moderate output signal-to-noise-and-distortion ratio of 46-59 dB (depending on the programmed gain). The merged functionality enables a better overall power/performance balance for the receiver baseband. The design consumes less than 2 mW and active area is 0.14 mm/sup 2/ in a 0.18-/spl mu/m digital CMOS technology.