Fast and Compact 16 by 16 Cellular Neural Network Implementation

The paper presents a Cellular Neural Network implementation based on a high gain sigmoid operation. The required simplifications to the original theory are described that allow the use of high gain. With this design black and white images can be processed. The basic building blocks in a cell are described. A 16×16 cells network has been designed and processed with 1.2 micron CMOS technology. Measurement results which show the operation of the network are presented.     

A Micropower Interface ASIC for a Capacitive 3-Axis Micro-Accelerometer

In this paper, a micropower interface IC for a capacitive 3-axis micro-accelerometer implemented in a 0.13- BiCMOS process is presented. The sensor interface consists of a front-end that converts the acceleration signal to voltage, two algorithmic ADCs, two frequency references, and a voltage, current, and temperature reference circuit. Die area and power dissipation are reduced by using time-multiplexed sampling and varying duty cycles down to 0.3%. The chip with a 0.51 active area draws 62 from a 1.8 V supply while sampling temperature at 100 Hz, and four proof masses, each at 1.04 kHz. With a 4-g capacitive 3-axis accelerometer, the measured noise floors in the x-, y-, and z-directions are 482 , 639 , and 662 , respectively.     

The Effect of Boundary Conditions on Gas-phase Synthesised Silver Nanoparticles

We have prepared spherical non-agglomerated silver nanoparticles by an evaporation–condensation–dilution/cooling technique. Silver was evaporated from a crucible in a tubular flow reactor. A porous tube diluter was used to quench the carrier gas at the outlet of the reactor to enhance the formation of small particles and to suppress agglomeration and other particle growth mechanisms. The number size distribution of the prepared particles was measured with a differential mobility analyser–condensation nucleus counter combination and the size and the shape of the particles were analysed with transmission electron microscope. The system was modelled using a sectional aerosol dynamics computer code to estimate the importance of different aerosol processes. In all conditions the particles obtained were non-agglomerated and spherical. The mean particle diameter varied from 4 to 10-nm depending on boundary conditions. From the modelling studies it can be concluded that the nucleation rate is the most important parameter controlling the final particle size.     

A digital quadrature modulator with on-chip D/A converter

The first analog IF mixer stage of a transmitter can be replaced with this digital quadrature modulator. The modulator interpolates orthogonal input carriers by 16 and performs digital quadrature modulation at carrier frequencies f/sub s//4, -f/sub s//4,f/sub s//2 (f/sub s/ is the sampling frequency). A 12-b digital-to-analog (D/A) converter is integrated with the digital quadrature modulator. A segmented current source architecture is combined with a proper switching technique to reduce spurious components and to enhance dynamic performance. The digital quadrature modulator is designed to fulfill the spectral, phase, and EVM specifications of GSM, EDGE, and WCDMA base stations. The die area of the chip is 27.09 mm/sup 2/ (0.35-/spl mu/m CMOS technology) and the total power consumption is 1.02 W with 2.8 V at 500-MHz output sampling rate (0.78-W digital modulator, 0.24-W D/A converter).     

A single-chip multimode receiver for GSM900, DCS1800, PCS1900, and WCDMA

A single-chip, multimode receiver for GSM900, DCS1800, PCS1900, and UTRA/FDD WCDMA is introduced in this paper. The receiver operates at four different radio frequencies with two different baseband bandwidths. The presented chip uses a direct-conversion architecture and consists of a low-noise amplifier (LNA), downconversion mixers with on-chip local-oscillator I/Q generation, channel selection filters, and programmable gain amplifiers. In spite of four receive bands, only four on-chip inductors are used in the single-ended LNA. The repeatable receiver second-order input intercept point (IIP2) of over +42 dBm is achieved with mixer linearization circuitry together with a baseband circuitry having approximately +100-dBV out-of-band IIP2. The noise figure of the SiGe BiCMOS receiver is less than 4.8 dB in all GSM modes, and 3.5 dB in WCDMA. The power consumption from a 2.7-V supply in all GSM modes and in WCDMA mode is 42 and 50 mW, respectively. The silicon area is 9.8 mm/sup 2/ including the bonding pads.     

Supercritical fluid extraction combined with solid phase extraction as sample preparation technique for the analysis of β-blockers in serum and urine

A method is developed for the determination of β-blockers in serum and urine at levels of 0.5 μg/mL. The technique uses a combination of solid phase extraction (SPE) with in situ derivatization and supercritical fluid extraction (SFE) with subsequent gas chromatography mass spectrometry. The optimization of the SFE step shows that a static extraction period can be eliminated. The method gives good linearity (r = 0.991–0.999) and repeatability in the concentration range of 0.5 to 5 μg/mL. Relative standard deviations for oxprenolol, propanolol and metoprolol were less than 5% in serum and 5–11% in urine. Received: 23 May 1997 / Revised: 28 July 1997 / Accepted: 5 August 1997     

Derivatives of pentamidine designed to target the Leishmania lipophosphoglycan

The Leishmania lipophosphoglycan (LPG) is the most abundant cell surface glycoconjugate of a family of infectious protozoa. Pentamidine, a common drug used in the treatment of Leishmania infections, has been modified with boronic acids so that it might bind more selectively to the phosphodisaccharide repeating unit of the LPG. This could serve to target the drug to the protozoan surface and increase its efficacy in vivo.     

Quantum-chemical gas-phase calculations on the protonation forms oftrans- andcis-urocanic acid

The neutral, cationic, and anionic structures of both prototropic tautomers oftrans- andcis-urocanic acid [(E)- and (Z)-3-(1H-imidazol-4(5)-yl)propenoic acid, respectively] were studied by using semiempirical andab initio gas-phase calculations. Potential energy surfaces of the structures were calculated by using the semiempirical AM1 method, and the geometries corresponding to global minima on these surfaces were optimized up to the MP2/6-31G^* level of theory. The calculated protonation forms of each urocanic acid isomer have a planar molecular structure due to a delocalized -electron system, and all of them prefer thes-trans conformation with respect to the bond between the imidazole and the propenoic acid moieties. Thecis-urocanic acid structures are stabilized by an intramolecular hydrogen bond. The chargedcis-urocanic acid isomers have a lower molecular energy than the correspondingtrans-isomers, whereas the neutral molecules have, after inclusion of thermodynamic corrections, approximately the same energy. The cationic urocanic acid structures have about 2500 kJ mol^–1 lower energy than the anionic ones and about 1000 kJ mol^–1 lower energy than the neutral ones. The nonzwitterionic forms of the neutral urocanic acid isomers have about 200 kJ mol^–1 lower energy than the zwitterionic ones. These energy differences are explained by the proton affinities of the imidazole and the propenoic acid moieties of the urocanic acid structures.