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Manufacturing cell formation using similarity coefficients and a parallel genetic TSP algorithm: Formulation and comparison 总被引:2,自引:0,他引:2
J. BalakrishnanP. D. Jog 《Mathematical and Computer Modelling》1995,21(12):61-73
Many algorithms have been proposed to form manufacturing cells from component routings. However, many of these do not have the capability of solving large problems. We propose a procedure using similarity coefficients and a parallel genetic implementation of a TSP algorithm that is capable of solving large problems of up to 1000 parts and 1000 machines. In addition, we also compare our procedure with many existing procedures using nine well-known problems from the literature.
The results show that the proposed procedure compares well with the existing procedures and should be useful to practitioners and researchers. 相似文献
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A new protocol for synthesis of 2-heterocylylacetic acid derivatives involving conjugate addition of allyl mercaptan to an acrylate containing a tethered olefinic site followed by RCM (ring-closing metathesis) is described. In this series, sulfanyl derivatives were unreactive, while sulfoxide and sulfone analogues provided the corresponding thiazocines in fair to excellent yields. Use of the sulfoxide oxidation state as a protecting group for sulfides inert to RCM is demonstrated also. Thus, oxidation of sulfide 9 [N-allyl-N-[2-(allylthio)-4-(1H-indol-1-yl)-4-oxobutyl]-4-methylbenzenesulfonamide] followed by cyclization yielded the corresponding thiazocine sulfoxide 12. Deprotection (deoxygenation) of 12 was accomplished using Lawesson's reagent, producing 1-[[4-[4-(methylphenyl)sulfonyl]-3,4,5,8-tetrahydro-2H-1,4-thiazocin-2-yl]acetyl]-1H-indole (21) in 67% unoptimized yield. 相似文献
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Several constitutive inequalities have been proposed in the literature to quantify the notion that ‘stress increases with strain’ in an elastic material. Due to some inherent shortcomings in them, which we discuss, we propose a new tensorial criterion for isotropic materials. We also present necessary conditions in terms of elasticity tensors for the onset of elastic instabilities. 相似文献
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Goran N. Kaluđerović Valentina Tayurskaya Reinhard Paschke Sanjiv Prashar Mariano Fajardo Santiago Gómez‐Ruiz 《应用有机金属化学》2010,24(9):656-662
The carboxylate compounds [Ti(η5‐C5H5)(η5‐C5H4{CMe2(CH2CH2CH?CH2)})(O2CCH2SXyl)2] (2; Xyl = 3,5‐Me2C6H3) and [Ti(η5‐C5H5)(η5‐C5H4{CMe2(CH2CH2CH?CH2)})(O2CCH2SMesl)2] (3; Mes 1 = 2,4,6‐Me3C6H2) were synthesized by the reaction of [Ti(η5‐C5H5)(η5‐C5H4{CMe2(CH2CH2CH?CH2)})Cl2] (1) with 2 equivalents of xylylthioacetic acid or mesitylthioacetic acid, respectively. Compounds 2 and 3 were characterized by spectroscopic methods. The cytotoxic activity of 1–3 was tested against human tumor cell lines from four different histogenic origins—8505C (anaplastic thyroid cancer), DLD‐1 (colon cancer) and the cisplatin sensitive A253 (head and neck cancer) and A549 (lung carcinoma)—and compared with those of the reference complex [Ti(η5‐C5H5)2Cl2] (R1) and cisplatin. Surprisingly, the cytotoxic activities of the carboxylate derivatives were lower than those of their corresponding dichloride analogue (1). However, complexes 1–3 were more active than titanocene dichloride against all the studied cells with the exception of complex 2 against A253 and A549 cell lines. DNA‐interaction tests were also carried out. Solutions of all the studied complexes were treated with different concentrations of fish sperm DNA, observing modifications of the UV spectra with intrinsic binding constants of 2.99 × 105, 2.45 × 105, and 2.35 × 105 M ?1 for 1–3. Structural studies based on density functional theory calculations of 2 and 3 were also carried out. Copyright © 2010 John Wiley & Sons, Ltd. 相似文献
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Rajendra A. Kalgaonkar Somnath Nandi Sanjeev S. Tambe Jyoti P. Jog 《Journal of Polymer Science.Polymer Physics》2004,42(14):2657-2666
The solid‐state viscoelastic properties are examined for intercalated nanocomposites based on a copolyester and (2‐ethyl‐hexyl)dimethyl hydrogenated‐tallow ammonium montmorillonite. The nanocomposites are prepared via the direct melt intercalation technique using a conventional twin‐screw extruder. Dynamic mechanical thermal analysis of the nanocomposites is conducted using two different test setups. The dynamic mechanical relaxation spectra show an increase in the storage modulus of the nanocomposite over the entire temperature range under study as compared to the pristine polymer (except in the transition region from 70 to 80 °C). These results are analyzed using the empirical Havriliak–Negami (HN) equation. The four temperature independent HN parameters (α, β, E0, and E∞) and one temperature dependent parameter (τ, the relaxation time) are determined by solving the HN equation for each temperature over the range of temperatures. The calculated moduli results fit well with the experimental values of the relaxation spectra for the nanocomposites. This study shows that the HN model can be applied to polymer layered silicate nanocomposites, and it can be used to predict their dynamic mechanical properties over a wide range of temperatures and frequencies a priori. © 2004 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 42: 2657–2666, 2004 相似文献
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Prashar D Cui D Bandyopadhyay D Luk YY 《Langmuir : the ACS journal of surfaces and colloids》2011,27(21):13091-13096
This work describes a general approach for preventing protein aggregation and surface adsorption by modifying proteins with β-cyclodextrins (βCD) via an efficient water-driven ligation. As compared to native unmodified proteins, the cyclodextrin-modified proteins (lysozyme and RNase A) exhibit significant reduction in aggregation, surface adsorption and increase in thermal stability. These results reveal a new chemistry for preventing protein aggregation and surface adsorption that is likely of different mechanisms than that by modifying proteins with poly(ethylene glycol). 相似文献
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C.S. Jog 《Journal of Elasticity》2002,66(2):159-169
A method for the explicit determination of the polar decomposition (and the related problem of finding tensor square roots) when the underlying vector space dimension n is arbitrary (but finite), is proposed. The method uses the spectral resolution, and avoids the determination of eigenvectors when the tensor is invertible. For any given dimension n, an appropriately constructed van der Monde matrix is shown to play a key role in the construction of each of the component matrices (and their inverses) in the polar decomposition. 相似文献