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排序方式: 共有919条查询结果,搜索用时 515 毫秒
1.
Da Hyeon Choi Jiwon Park Ju Kwang Choi Kyeong Eun Lee Won Hee Lee Jinho Yang Ju Yeon Lee Yoon Jeong Park Chan Oh Ho-Ryun Won Bon Seok Koo Jae Won Chang Yoon Shin Park 《Experimental & molecular medicine》2020,52(9):1564
Oral microbes have the capacity to spread throughout the gastrointestinal system and are strongly associated with multiple diseases. Given that tonsils are located between the oral cavity and the laryngopharynx at the gateway of the alimentary and respiratory tracts, tonsillar tissue may also be affected by microbiota from both the oral cavity (saliva) and the alimentary tract. Here, we analyzed the distribution and association of the microbial communities in the saliva and tonsils of Korean children subjected to tonsillectomy because of tonsil hyperplasia (n = 29). The microbiome profiles of saliva and tonsils were established via 16S rRNA gene sequencing. Based on the alpha diversity indices, the microbial communities of the two groups showed high similarities. According to Spearman’s ranking correlation analysis, the distribution of Treponema, the causative bacterium of periodontitis, in saliva and tonsils was found to have a significant positive correlation. Two representative microbes, Prevotella in saliva and Alloprevotella in tonsils, were negatively correlated, while Treponema 2 showed a strong positive correlation between saliva and tonsils. Taken together, strong similarities in the microbial communities of the tonsils and saliva are evident in terms of diversity and composition. The saliva microbiome is expected to significantly affect the tonsil microbiome. Furthermore, we suggest that our study creates an opportunity for tonsillar microbiome research to facilitate the development of novel microbiome-based therapeutic strategies.Subject terms: Comparative genomics, Metagenomics 相似文献
2.
Sung Hwan Koo Dong Jun Li Taeyeong Yun Dong Sung Choi Kyung Eun Lee Gil Yong Lee Youngtak Oh Joonwon Lim Suchithra Padmajan Sasikala Ho Jin Lee In Ho Kim Hong Ju Jung Rishabh Jain Sang Ouk Kim 《Particle & Particle Systems Characterization》2019,36(7)
Efficient water electrolysis catalyst is highly demanded for the production of hydrogen as a sustainable energy fuel. It is reported that cobalt derived nanoparticle (CoS2, CoP, CoS|P) decorated reduced graphene oxide (rGO) composite aerogel catalysts for highly active and reliable hydrogen evolution reaction electrocatalysts. 7 nm level cobalt derived nanoparticles are synthesized over graphene aerogel surfaces with excellent surface coverage and maximal expose of active sites. CoS|P/rGO hybrid aerogel composites show an excellent catalytic activity with overpotential of ≈169 mV at a current density of ≈10 mA cm?2. Accordingly, efficient charge transfer is attained with Tafel slope of ≈52 mV dec?1 and a charge transfer resistance (Rct) of ≈12 Ω. This work suggests a viable route toward ultrasmall, uniform nanoparticles decorated graphene surfaces with well‐controlled chemical compositions, which can be generally useful for various applications commonly requiring large exposure of active surface area as well as robust interparticle charger transfer. 相似文献
3.
Dong-Soo Yoon Jae Sung Roh Sung-Man Lee Hong Koo Baik 《Journal of Electronic Materials》2003,32(8):890-898
The effect of a thin RuOx layer formed on the Ru/TiN/doped poly-Si/Si stack structure was compared with that on the RuOx/TiN/doped poly-Si/Si stack structure over the post-deposition annealing temperature ranges of 450–600°C. The Ru/TiN/poly-Si/Si
contact system exhibited linear behavior at forward bias with a small increase in the total resistance up to 600°C. The RuOx/TiN/poly-Si/Si contact system exhibited nonlinear characteristics under forward bias at 450°C, which is attributed to no
formation of a thin RuOx layer at the RuOx surface and porous-amorphous microstructure. In the former case, the addition of oxygen at the surface layer of the Ru film
by pre-annealing leads to the formation of a thin RuOx layer and chemically strong Ru-O bonds. This results from the retardation of oxygen diffusion caused by the discontinuity
of diffusion paths. In particular, the RuOx layer in a nonstoichiometric state is changed to the RuO2-crystalline phase in a stoichiometric state after post-deposition annealing; this phase can act as an oxygen-capture layer.
Therefore, it appears that the electrical properties of the Ru/TiN/poly-Si/Si contact system are better than those of the
RuOx/TiN/poly-Si/Si contact system. 相似文献
4.
J.-P. Han S.M. Koo E.M. Vogel E.P. Gusev C. DEmic C.A. Richter J.S. Suehle 《Microelectronics Reliability》2005,45(5-6):783
Anomalous threshold voltage roll-up behavior, commonly referred as reverse short channel effect (RSCE), has been observed in high-k (HfO2 on SiON buffer, Al2O3 on SiON buffer) gated submicron nMOSFETs, while the SiO2 or SiON control samples show normal short channel effect (SCE) behavior. The possible causes such as inhomogeneous channel doping profile and gate oxide thickness variation near S/D ends have been ruled out. The results indicate that interface trap density that dependents on channel length is the main cause of the RSCE observed here. In addition, oxide charge also plays a role. 相似文献
5.
Dong Il Han Hoe Jin Hah Hong-Woo Park Sang Man Koo 《Journal of Sol-Gel Science and Technology》2004,32(1-3):47-51
Composite silica particles were synthesized by a two-step (acid-base) process in an aqueous solution with a mixture of organoalkoxysilane monomers. The two-step process separates the hydrolysis and condensation procedures to easily control condensation rate. In this study, the silane monomers used were phenyltrimethoxysilane (PTMS), vinyltrimethoxysilane (VTMS), methyltrimethoxysilane (MTMS), and tetraethyl-orthosilicate (TEOS). The physical properties of the resultant composite particles were investigated with the change in the molar ratio of monomers. The size of the particles increased with increasing the molar ratio of RaSi(OR)3/RbSi(OR)3 or RaSi(OR)3/TEOS (Ra: phenyl; Rb: vinyl, methyl). 相似文献
6.
Eunseok Song Yido Koo Yeon-Jae Jung Deok-Hee Lee Sangyoung Chu Soo-Ik Chae 《Solid-State Circuits, IEEE Journal of》2005,40(5):1094-1106
This paper describes a single-chip CMOS quad-band (850/900/1800/1900 MHz) RF transceiver for GSM/GPRS applications. It is the most important design issue to maximize resource sharing and reuse in designing the multiband transceivers. In particular, reducing the number of voltage-controlled oscillators (VCOs) required for local oscillator (LO) frequency generation is very important because the VCO and phase-locked loop (PLL) circuits occupy a relatively large area. We propose a quad-band GSM transceiver architecture that employs a direct conversion receiver and an offset PLL transmitter, which requires only one VCO/PLL to generate LO signals by using an efficient LO frequency plan. In the receive path, four separate LNAs are used for each band, and two down-conversion mixers are used, one for the low bands (850/900 MHz) and the other for the high bands (1800/1900 MHz). A receiver baseband circuit is shared for all four bands because all of their channel spaces are the same. In the transmit path, most of the building blocks of the offset PLL, including a TX VCO and IF filters, are integrated. The quad-band GSM transceiver that was implemented in 0.25-/spl mu/m CMOS technology has a size of 3.3/spl times/3.2 mm/sup 2/, including its pad area. From the experimental results, we found that the receiver provides a maximum noise figure of 2.9 dB and a minimum IIP3 of -13.2dBm for the EGSM 900 band. The transmitter shows an rms phase error of 1.4/spl deg/ and meets the GSM spectral mask specification. The prototype chip consumes 56 and 58 mA at 2.8 V in the RX and TX modes, respectively. 相似文献
7.
Jenghwa Chang Graber H.L. Ping Chen Koo Aronson R. Barbour S.-L.S. Barbour R.L. 《IEEE transactions on medical imaging》1997,16(1):68-77
Presents a model suitable for computing images of absorption cross sections of thick tissue structures illuminated at near infrared (NIR) wavelengths from tomographic projection data. Image reconstruction is accomplished by solving a system of linear equations derived from transport theory. Reconstruction results using different algebraic solvers are shown for anatomical maps of the breast, derived from magnetic resonance imaging data, containing two simulated pathologies, in which case qualitatively good reconstructions were obtained. Evaluation of magnetic resonance (MR) data to optimize NIR optical tomographic imaging methods and to assess the feasibility of a combined MR-optical measurement scheme is discussed 相似文献
8.
Effects of hysteretic and aerodynamic damping on supersonic panel flutter of composite plates 总被引:1,自引:0,他引:1
The governing equation for the finite element analysis of the panel flutter of composite plates including structural damping is derived from Hamilton's principle. The first order shear deformable plate theory has been applied to structural modelling so as to obtain the finite element eigenvalue equation. The unsteady aerodynamic load in a supersonic flow is computed by using the linear piston theory. The critical dynamic pressures for composite plates have been calculated to investigate the effects of structural damping on flutter boundaries. The effects are dependent on fiber orientation because flutter mode can be weak or strong in the fiber orientation of composite plates. Structural damping plays an important role in flutter stability with low aerodynamic damping but would not affect the flutter boundary with high aerodynamic damping. 相似文献
9.
On the harmonic Bergman space of the half-space, we give characterizations for an arbitrary positive Toeplitz operator to
be a Schatten (or Schatten-Herz) class operator in terms of averaging functions and Berezin transforms. Examples are provided
to show that various results are sharp.
This research was supported by KOSEF(R01-2003-000-10243-0). 相似文献
10.
Koo K.P. Bucholtz F. Dagenais D.M. Dandridge A. 《Photonics Technology Letters, IEEE》1989,1(12):464-466
A compact fiber-optic magnetometer constructed using a short piece of amorphous metal wire (5-cm long×100-μm diameter) as the magnetostrictive transducer is discussed. The inherently large ratio of length to cross-sectional area results in a low demagnetization along the axial direction. A magnetostrictive constant of 5×10-5 /Oe2, which is 10-50 times larger than the reported values for transducers made from Metglas ribbons, was measured. Minimum detectable magnetic fields on the order of 10-5 Oe/Hz1/2 at 1 Hz were achieved using a 5-cm-long sensing fiber 相似文献