排序方式: 共有176条查询结果,搜索用时 0 毫秒
1.
2.
Green and one‐pot surface coating of iron oxide magnetic nanoparticles with natural amino acids and biocompatibility investigation 下载免费PDF全文
Hamed Nosrati Marziyeh Salehiabar Elahe Attari Soodabeh Davaran Hossein Danafar Hamidreza Kheiri Manjili 《应用有机金属化学》2018,32(2)
We report the synthesis of iron oxide magnetic nanoparticles (IONPs) coated with various natural amino acids (AAs) using a one‐pot reaction in an aqueous medium. Several AAs, which contained hydrophilic and hydrophobic groups, were selected to study their effects on size, morphology and toxicity of IONPs. Functionalized IONPs were characterized using X‐ray diffraction, differential scanning calorimetry, thermogravimetric analysis, Fourier transform infrared spectroscopy, and scanning and transmission electron microscopies. Furthermore, vibrating sample magnetometry analysis shows these nanoparticles have excellent magnetic properties. Cellular toxicity of IONPs was also investigated on HFF2 cell lines. The AA‐coated IONPs are non‐toxic and biocompatible. Natural AA‐coated IONPs show a potential for their development in in vitro and in vivo biomedical fields due to their non‐toxicity, good ζ‐potential and related small size and narrow size distribution. 相似文献
3.
Synthesis of Depo‐Medrol–chitosan hydrogel as new drug slow‐release appliance and investigation of release kinetics by high‐performance liquid chromatography 下载免费PDF全文
Reza Alizadeh Sara Majd Jabbari Amir H. Zarnani Hamidreza Barghi 《Biomedical chromatography : BMC》2016,30(9):1346-1353
The present study deals with preparation and optimization of a novel chitosan hydrogel‐based matrix by suspension cross‐linking method for controlled release of Depo‐Medrol. The controlled release of Depo‐Medrol for effective Rheumatoid arthritis disease has become an imperative field in the drug delivery system. In this context, it was intended to optimize loading circumstances by experimental design and also study the release kinetics of Depo‐Medrol entrapped in the chitosan matrix in order to obtain maximal efficiency for drug loading. The optimum concentrations of chitosan (2.5 g), glutaraldehyde (3.05 μL) and Depo‐Medrol (0.1 mg) were set up to achieve the highest value of drug loaded and the most sustained release from the chitosan matrix. In vitro monitoring of drug release kinetic using high‐performance liquid chromatography showed that 73% of the Depo‐Medrol was released within 120 min, whereas remained drug was released during the next 67 h. High correlation between first‐order and Higuchi's kinetic models indicates a controlled diffusion of Depo‐Medrol through the surrounding media. Moreover, recovery capacity >82% and entrapment efficiency of 58–88% were achieved under optimal conditions. Therefore, the new synthesized Depo Medrol–chitosan is an applicable appliance for arthritis therapy by slow release mechanism. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献
4.
In this work, the films of poly(ether-block-amide) (Pebax 1657) and hydrophilic/hydrophobic silica nanoparticles (0–10 wt%) were coated on a poly(vinyl chloride) (PVC) ultrafiltration membrane to form new mixed matrix composite membranes (MMCMs) for CO2/N2 separation. The membranes were characterized by SEM, FTIR, DSC and XRD. Successful formation of a non-porous defect-free dense top layer with ~4 μm of thickness and also uniform dispersion of silica nanoparticles up to 8 wt% loading in Pebax matrix were confirmed by SEM images. The gas permeation results showed an increase in the permeance of all gases and an increase in ideal CO2/N2 selectivity with the increase in silica nanoparticle contents. Comparison between the incorporation of hydrophilic and hydrophobic silica nanoparticle into Pebax matrix revealed that the great enhancement of CO2 solubility is the key factor for the performance improvement of Pebax + silica nanoparticle membranes. The best separation performance of the hydrophilic silica nanoparticle-incorporated Pebax/PVC membrane for pure gases (at 1 bar and 25 °C) was obtained with a CO2 permeability of 124 barrer and an ideal CO2/N2 selectivity of 76, i.e., 63 and 35% higher than those of neat Pebax membrane, respectively. The corresponding values for hydrophobic silica nanoparticle-incorporated Pebax/PVC membrane were 107 barrer for CO2 permeability and 61 for ideal CO2/N2 selectivity. Also the performances of MMCMs improved upon pressure increase (1–10 bar) owing to the shift in plasticizing effect of CO2 towards the higher pressures. In addition, an increase in permeabilities with a decrease in ideal selectivity was observed upon temperature increase (25–50 °C) due to the intensification of chain mobility. 相似文献
5.
6.
Rostami Mojtaba Aghajanzadeh Mozhgan Zamani Mostafa Manjili Hamidreza Kheiri Danafar Hossein 《Research on Chemical Intermediates》2018,44(3):1889-1904
Research on Chemical Intermediates - In this study, a kind of magnetic Fe3O4@mTiO2-GO (where m was shorted mesoporous) hybrids with core–shell nano-structure for controlled dual targeted drug... 相似文献
7.
8.
Journal of Solid State Electrochemistry - We report the electrochemical behavior of free-standing functionalized graphene sheet electrode in a potential window corresponding to that of high-voltage... 相似文献
9.
A fast Pareto genetic algorithm approach for solving expensive multiobjective optimization problems 总被引:1,自引:0,他引:1
We present a new multiobjective evolutionary algorithm (MOEA), called fast Pareto genetic algorithm (FastPGA), for the simultaneous
optimization of multiple objectives where each solution evaluation is computationally- and/or financially-expensive. This
is often the case when there are time or resource constraints involved in finding a solution. FastPGA utilizes a new ranking
strategy that utilizes more information about Pareto dominance among solutions and niching relations. New genetic operators
are employed to enhance the proposed algorithm’s performance in terms of convergence behavior and computational effort as
rapid convergence is of utmost concern and highly desired when solving expensive multiobjective optimization problems (MOPs).
Computational results for a number of test problems indicate that FastPGA is a promising approach. FastPGA yields similar
performance to that of the improved nondominated sorting genetic algorithm (NSGA-II), a widely-accepted benchmark in the MOEA
research community. However, FastPGA outperforms NSGA-II when only a small number of solution evaluations are permitted, as
would be the case when solving expensive MOPs. 相似文献
10.
Hamidreza Esmaielpour Vincent R. Whiteside Jinfeng Tang Sangeetha Vijeyaragunathan Tetsuya D. Mishima Shayne Cairns Michael B. Santos Bin Wang Ian R. Sellers 《Progress in Photovoltaics: Research and Applications》2016,24(5):591-599
InAs/AlAsxSb1 − x quantum wells are investigated for their potential as hot carrier solar cells. Continuous wave power and temperature‐dependent photoluminescence indicate a transition in the dominant hot carrier relaxation process from conventional phonon‐mediated carrier relaxation below 90 K to a regime where inhibited radiative recombination dominates the hot carrier relaxation at elevated temperatures. At temperatures below 90 K, photoluminescence measurements are consistent with type‐I quantum wells that exhibit hole localization associated with alloy/interface fluctuations. At elevated temperatures, hole delocalization reveals the true type‐II band alignment, where it is observed that inhibited radiative recombination due to the spatial separation of the charge carriers dominates hot carrier relaxation. This decoupling of phonon‐mediated relaxation results in robust hot carriers at higher temperatures, even at lower excitation powers. These results indicate type‐II quantum wells offer potential as practical hot carrier systems. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献