首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   1245篇
  免费   40篇
  国内免费   6篇
化学   810篇
晶体学   6篇
力学   28篇
数学   195篇
物理学   150篇
无线电   102篇
  2022年   21篇
  2021年   19篇
  2020年   29篇
  2019年   31篇
  2018年   15篇
  2017年   17篇
  2016年   23篇
  2015年   23篇
  2014年   44篇
  2013年   49篇
  2012年   77篇
  2011年   86篇
  2010年   45篇
  2009年   47篇
  2008年   61篇
  2007年   81篇
  2006年   77篇
  2005年   59篇
  2004年   62篇
  2003年   53篇
  2002年   57篇
  2001年   17篇
  2000年   21篇
  1999年   17篇
  1998年   6篇
  1997年   14篇
  1996年   12篇
  1995年   22篇
  1994年   22篇
  1993年   10篇
  1992年   13篇
  1991年   7篇
  1990年   10篇
  1988年   6篇
  1987年   9篇
  1986年   12篇
  1985年   9篇
  1984年   9篇
  1983年   12篇
  1982年   7篇
  1981年   13篇
  1980年   4篇
  1979年   5篇
  1978年   5篇
  1977年   6篇
  1976年   6篇
  1975年   8篇
  1974年   5篇
  1973年   5篇
  1969年   5篇
排序方式: 共有1291条查询结果,搜索用时 15 毫秒
1.
Treating neuroinflammation-related injuries and disorders through manipulation of neuroinflammation functions is being heralded as a new therapeutic strategy. In this study, a novel pectic galactan (PG) polysaccharide based gene therapy approach is developed for targeting reactive gliosis in neuroinflammation. Galectin-3 (Gal-3) is a cell protein with a high affinity to β-galactoside sugars and is highly expressed in reactive gliosis. Since PG carries galactans, it can target reactive gliosis via specific carbohydrate interaction between galactan and Gal-3 on the cell membrane, and therefore can be utilized as a carrier for delivering genes to these cells. The carrier is synthesized by modifying quaternary ammonium groups on the PG. The resulting quaternized PG (QPG) is found to form complexes with plasmid DNA with a mean diameter of 100 nm and have the characteristics required for targeted gene therapy. The complexes efficiently condense large amounts of plasmid per particle and successfully bind to Gal-3. The in vivo study shows that the complexes are biocompatible and safe for administration and can selectively transfect reactive glial cells of an induced cortical lesion. The results confirm that this PG-based delivery system is a promising platform for targeting Gal-3 overexpressing neuroinflammation cells for treating neuroinflammation-related injuries and neurodegenerative diseases.  相似文献   
2.
3.
4.
This study investigated jurors' reactions to judges' nonverbal communication in mock trials. Participants in 80 mock juries viewed taped segments of direct and cross examination that varied the judges' level of nonverbal involvement. Comments about the judge were solicited in predeliberation questionnaires and unsolicited comments obtained from dialogue that occurred during mock jury deliberations. The investigation found that jurors are aware of nonverbal cues from judges, particularly negative behaviors. Although the high- and low-involved judges solicited roughly the same number of comments, more negative comments were made about the judge displaying low than high nonverbal involvement. The results also revealed that jurors made more negative comments than positive ones. Overall, jurors are most aware of a judge's lack of involvement and apparent bias. Discussion focuses on ways to minimize the influence of judge nonverbal communication on jurors.  相似文献   
5.
Ann R Thryft 《电子设计技术》2008,15(7):78-78,80,82,84,86
数年来,具有10Gbps速度的下一代以太网一直处于即将成为主流的状况。一段时间以来,网络的某些区域已在使用光学技术,并且随着流量的增加,对10GbE数据速率的需求正在增长。但是,需要一种比上一代以太网复杂许多的技术,用于在100m长的铜缆上运行10GbE。这一要求导致了昂贵的MAC(媒体访问控制器)和交换芯片,以及昂贵而又不方便的PHY层接口芯片,由此限制了快速LAN用于那些覆盖数据中心内较短距离的高性能应用。  相似文献   
6.
Described is a method of introducing trifluoroalkyl groups at C-6 of lysine. This chemistry has the potential to introduce a variety of functionality at C-6 of lysine.  相似文献   
7.
The effective propagation rate constant (kp; averaged over all the propagating active centers) was characterized for solvent‐free cationic photopolymerizations of phenyl glycidyl ether over the entire range of conversions, including the high conversion regime in which mass transfer limitations become important. The profile for the kp as a function of conversion was found to exhibit a constant plateau value at low to intermediate conversions, followed by a monotonic increase above a threshold value of conversion. To explain this trend, it is proposed that at high conversion the diffusional mobility of the photoinitiator counterion is reduced whereas the mobility of the cationic active center remains high because of reactive diffusion. Therefore, with increasing conversion, the average distance between the active centers and counterions may increase, resulting in an increase in the propagation rate constant. The profiles for the kp values were investigated as a function of the temperature, photoinitiator anion, and photoinitiator concentration. As the photoinitiator concentration was increased, the plateau value of the effective propagation rate constant decreased whereas the threshold conversion increased. All of the experimental trends are consistent with the proposed increase in ion separation at high conversions. © 2004 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 42: 4409–4416, 2004  相似文献   
8.
9.
10.
The authors propose a method to estimate the synchronisation offset for orthogonal frequency division multiplexing (OFDM) frame alignment without resort to pilot tones. A decision-directed maximum-likelihood estimation of frame synchronisation offset is derived, and the performance of the proposed scheme is confirmed by computer simulation for QAM systems  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号