Integration of millimeter-wave and optical link for duplex transmission of hierarchically modulated signal over a single carrier and fiber for future 5G communication systems

Telecommunication Systems - Integration of optical and millimeter-wave systems provide a promising solution for future giga-bits per second wireless communication systems. We have proposed and...     

{^6_{\Lambda} \rm{H}} Modeled as {^4_{\Lambda} \rm{H}} + n + n

A three-body calculation for the \({^4_{\Lambda} \rm{He}}\) and \({^6_{\Lambda}{\rm H}}\) hypernuclei has been undertaken. The respective cores are \({^4_{\Lambda}{\rm H}}\) . The interactions in the \({^6_{\Lambda}{\rm He}}\) system, modeled as \({^4_{\Lambda} {\rm H+p+n}}\) , are reasonably well known. For example, the p n interaction is well determined by the p n scattering data, the \({^4_{\Lambda}{\rm H}}\) –p interaction can be fitted to the \({^5_{\Lambda}{\rm He}}\) binding energy. The \({^4_{\Lambda}{\rm He}}\) –n interaction can be fitted to α–n scattering data. For the ⁴He–n system the s-wave can be modeled alternatively as a repulsive potential or as an attractive potential with a forbidden bound state. We explore these alternatives in ⁶He, because the interaction comes into play in modeling \({^6_{\Lambda}{\rm He}}\) as well as in our \({^4_{\Lambda}{\rm H}}\) + n + n model of \({^6_{\Lambda}{\rm H}}\) , where the valence neutrons are Pauli blocked from the s-shell of the core nucleus.     

A Review of HER4 (ErbB4) Kinase,Its Impact on Cancer,and Its Inhibitors

HER4 is a receptor tyrosine kinase that is required for the evolution of normal body systems such as cardiovascular, nervous, and endocrine systems, especially the mammary glands. It is activated through ligand binding and activates MAPKs and PI3K/AKT pathways. HER4 is commonly expressed in many human tissues, both adult and fetal. It is important to understand the role of HER4 in the treatment of many disorders. Many studies were also conducted on the role of HER4 in tumors and its tumor suppressor function. Mostly, overexpression of HER4 kinase results in cancer development. In the present article, we reviewed the structure, location, ligands, physiological functions of HER4, and its relationship to different cancer types. HER4 inhibitors reported mainly from 2016 to the present were reviewed as well.     

In silico ADME predictions and in vitro antibacterial evaluation of 2-hydroxy benzothiazole-based 1,3,4-oxadiazole derivatives

In the present work, a library of fifteen 2-hydroxy benzothiazole-linked 1,3,4 -oxadiazole derivatives have been synthesized and confirmed using different analytical techniques. All of the synthesized compounds have been tested for antibacterial and in silico pharmacokinetic studies for the first time. From the ADME predictions, compound 4 showed the highest in silico absorption percentage (86.77%), while most of the compounds showed more than 70% absorption. All of the compounds comply with the Lipinski rule of 5, suggesting that the compounds possess good drug likeness properties upon administration. Furthermore, all of the compounds follow the Veber rule, indicating good bioavailability and good intestinal absorption. The antibacterial results exhibited excellent to moderate activity. Compounds 5 , 9 , 12 , 14 , 15 , 16 , and 17 were the most active compounds against the tested bacterial strains. Compound 14 showed comparable MIC 6.25 ±0.2 μg/disc to the standard drug amoxicillin against the tested Gram-positive bacterial strains. Compounds 5 , 14 , 17 exhibited MIC 12.5 ±0.8 μg/disc, which was comparable to the standard drug against E. faecalis . It can be concluded that the synthesized compound could be used as a lead molecule in the development of new antibacterial agents with high efficacy.     

The Triton from the Reid93 Potential in the UPA

The unitary pole approximation (UPA) provides an effective means to construct a rank one separable potential for calculations in which one requires a simple representation of the deuteron and/or triton ground-state wave function. By construction the deuteron wave function and the ¹S₀ anti-bound state wave function of the original potential are reproduced. We report results for the corresponding triton ground state. We choose to utilize the realistic Reid93 potential for this purpose. The Reid93 potential, generated by the Nijmegen group, is a Reid-like, partial-wave local potential that produces a χ² representation of the nucleon–nucleon (NN) scattering data that is as precise as an NN partial-wave analysis. Results for properties of ²H and ³H from the UPA are compared with those for the original potential. To further illustrate the precision of the method, results for properties of the deuteron and triton from the UPA are also compared with those for the original Reid68 potential.     

Off-shell effects in the three-nucleon bound state

Phase-shift-equivalent separable potentials are used to study the sensitivity of the triton binding energy E_T to the off-shell behavior of the two-nucleon T matrix. It is found that the deuteron wave function significantly constrains the theoretical uncertainty in E_T and that the properties of the off-shell T matrix at intermediate energies are only weakly reflected in E_T.     

Synthesis of some new 2-substituted-4-sulfamoylphenylazo-thiophene and/or thiazole derivatives as antibacterial agents

Benzoylacetone has been reacted with phenyl isothiocyanate to afford two different thiocarbamoyl derivatives (α-phenylthiocarbamoyl benzoylacetone and benzoyl thioacetanilide) depending upon the base used to perform the reaction. Several new 2-substituted-4-sulfamoylphenylazo-thiophene and/or thiazole derivatives were synthesized by heterocyclization of the thiocarbamoyl derivatives with various halogenated reagents. The synthesized compounds were screened for their antibacterial activities; they showed accepted activities with respect to the control drugs.     

Transient behaviour in RDA systems of the Schnakenberg type

Initial stages in the evolution of linear disturbances near a homogeneous equilibrium are considered for the standard Schnakenberg and modified Schnakenberg models. The focus is on a possibility of transient amplification of perturbations. It is shown that, depending on the coefficients in the governing equations, transient growth may appear in both asymptotically stable and unstable situations.     

Solvent free oxidation of primary alcohols and diols using thymine iron(III) catalyst

In this study, we developed an efficient and selective iron-based catalyst system for the synthesis of ketones from secondary alcohols and carboxylic acids from primary alcohol. In situ generated iron catalyst of thymine-1-acetate (THA) and FeCl(3) under solvent-free condition exhibits high activity. As an example, 1-octanol and 2-octanol were oxidized to 1-octanoic acid and 2-octanone with 89% and 98% yields respectively.