Micro-vibrating spatial filters-induced beam positioning stability in large laser system

A dynamic beam propagation model of micro-vibrating spatial filters in inertial confinement fusion(ICF) facilities is built based on the additional beam in SG-II facility.The transfer matrix is then deduced,and the sensitivities of the beam positioning to the pellet in the target area to the vibrations of every spatial filter are analyzed,which indicates that the vibrations of spatial filters in the pre-amplify zone has less effects on beam positioning stability at the target.In addition,the vibrations of spatial filters in the main amplify zone dominates the beam positioning stability of the target,especially the vibration of the spatial filter SF7.     

扫描离子电导显微镜及其在医学研究中的初步应用

扫描离子电导显微镜(scanning ion conductance microscopy,SICM)是一种非接触式的扫描探针显微技术(scanning probe microscopy,SPM),可以实现生物样品在近生理条件下的成像.随着技术发展,目前广泛应用于生物医学领域的SICM主要包括两种:跳跃式离子电导显微技术(hopping probe ion conductance microscopy,HPICM)和外加压力模式的SICM.前者可以应用于软的、黏的、对外力或其它机械信号敏感的样品的高分辨成像;后者可以通过探针微管对样品局部施加外力刺激或化学、电学、光学或生物分子等信号,实现对样品动力学性质或相关生理过程局部的原位研究.此外,SICM技术具有良好的开放性,能够越来越多地与其它技术手段联用,极大地丰富了其在生物医学领域的应用,可用于疾病发病机理、药物作用以及临床诊断等的研究.但是,目前SICM时间分辨率较低,这制约了它在生物体系动力学行为方面的研究.