Effects of signal-to-noise ratio, signal periodicity, and degree of hearing impairment on the performance of voice-separation algorithms

Procedures for enhancing the intelligibility of a target talker in the presence of a co-channel competing talker were evaluated in tests involving (i) continuously voiced sentences spoken on a monotone, (ii) continuously voiced sentences with time-varying intonation, and (iii) noncontinuously voiced sentences produced with natural intonation. The procedures were based on the methods of harmonic selection and cepstral filtering [R.J. Stubbs and Q. Summerfield, J. Acoust. Soc. Am. 87, 359-372 (1990)]. Target and competing voices were combined at signal-to-noise ratios (SNRs) between -10 dB and +10 dB. Subjects were a group with normal hearing and a heterogeneous group with mild-moderate cochlear hearing impairments. Processing enhanced the target voice over a range of SNRs for each type of sentence and for most listeners. Enhancement was greatest at negative SNRs. Among the impaired listeners, benefit was generally greater for those with milder losses. These results consolidate and extend previous demonstrations that voice-separation algorithms that exploit the harmonic structure of the voiced portions of speech can enhance intelligibility. However, practical application of such algorithms depends on a solution to the problem of tracking the fundamental-frequency contour of one voice in the presence of a competing voice.     

Effective medium theory of A.C. Hopping conductivity for random-bond lattice models

We apply standard effective medium techniques to calculate the A.C. hopping conductivity of a system where the sites are located on a regular lattice but the intersite hop-rate is a random variable. The method is a generalization of Kirkpatrick's treatment of the D.C. conductivity of such a system. The results are compared with exact solution of the one-dimensional bond percolation problem and good agreement is found.     

Algorithms for separating the speech of interfering talkers: evaluations with voiced sentences, and normal-hearing and hearing-impaired listeners

Two signal-processing algorithms, derived from those described by Stubbs and Summerfield [R.J. Stubbs and Q. Summerfield, J. Acoust. Soc. Am. 84, 1236-1249 (1988)], were used to separate the voiced speech of two talkers speaking simultaneously, at similar intensities, in a single channel. Both algorithms use fundamental frequency (FO) as the basis for segregation. One attenuates the interfering voice by filtering the cepstrum of the signal. The other is a hybrid algorithm that combines cepstral filtering with the technique of harmonic selection [T.W. Parsons, J. Acoust. Soc. Am. 60, 911-918 (1976)]. The algorithms were evaluated and compared in perceptual experiments involving listeners with normal hearing and listeners with cochlear hearing impairments. In experiment 1 the processing was used to separate voiced sentences spoken on a monotone. Both algorithms gave significant increases in intelligibility to both groups of listeners. The improvements were equivalent to an increase of 3-4 dB in the effective signal-to-noise ratio (SNR). In experiment 2 the processing was used to separate voiced sentences spoken with time-varying intonation. For normal-hearing listeners, cepstral filtering gave a significant increase in intelligibility, while the hybrid algorithm gave an increase that was on the margins of significance (p = 0.06). The improvements were equivalent to an increase of 2-3 dB in the effective SNR. For impaired listeners, no intelligibility improvements were demonstrated with intoned sentences. The decrease in performance for intoned material is attributed to limitations of the algorithms when FO is nonstationary.     

Ultrafast delocalization of excitation in synthetic light-harvesting nanorings

Rings of chlorophyll molecules harvest sunlight remarkably efficiently during photosynthesis in purple bacteria. The key to their efficiency lies in their highly delocalized excited states that allow for ultrafast energy migration. Here we show that a family of synthetic nanorings mimic the ultrafast energy transfer and delocalization observed in nature. π-Conjugated nanorings with diameters of up to 10 nm, consisting of up to 24 porphyrin units, are found to exhibit excitation delocalization within the first 200 fs of light absorption. Transitions from the first singlet excited state of the circular nanorings are dipole-forbidden as a result of symmetry constraints, but these selection rules can be lifted through static and dynamic distortions of the rings. The increase in the radiative emission rate in the larger nanorings correlates with an increase in static disorder expected from Monte Carlo simulations. For highly symmetric rings, the radiative rate is found to increase with increasing temperature. Although this type of thermally activated superradiance has been theoretically predicted in circular chromophore arrays, it has not previously been observed in any natural or synthetic systems. As expected, the activation energy for emission increases when a nanoring is fixed in a circular conformation by coordination to a radial template. These nanorings offer extended chromophores with high excitation delocalization that is remarkably stable against thermally induced disorder. Such findings open new opportunities for exploring coherence effects in nanometer molecular rings and for implementing these biomimetic light-harvesters in man-made devices.     

Evaluation of two voice-separation algorithms using normal-hearing and hearing-impaired listeners

Two signal-processing algorithms, designed to separate the voiced speech of two talkers speaking simultaneously at similar intensities in a single channel, were compared and evaluated. Both algorithms exploit the harmonic structure of voiced speech and require a difference in fundamental frequency (F0) between the voices to operate successfully. One attenuates the interfering voice by filtering the cepstrum of the combined signal. The other uses the method of harmonic selection [T. W. Parsons, J. Acoust. Soc. Am. 60, 911-918 (1976)] to resynthesize the target voice from fragmentary spectral information. Two perceptual evaluations were carried out. One involved the separation of pairs of vowels synthesized on static F0's; the other involved the recovery of consonant-vowel (CV) words masked by a synthesized vowel. Normal-hearing listeners and four listeners with moderate-to-severe, bilateral, symmetrical, sensorineural hearing impairments were tested. All listeners showed increased accuracy of identification when the target voice was enhanced by processing. The vowel-identification data show that intelligibility enhancement is possible over a range of F0 separations between the target and interfering voice. The recovery of CV words demonstrates that the processing is valid not only for spectrally static vowels but also for less intense time-varying voiced consonants. The results for the impaired listeners suggest that the algorithms may be applicable as components of a noise-reduction system in future digital signal-processing hearing aids. The vowel-separation test, and subjective listening, suggest that harmonic selection, which is the more computationally expensive method, produces the more effective voice separation.     

Mixing of phases in non-crystalline materials: Application to carbon

The atomic structure of non-crystalline solids is described by the correlation function. When more than one phase is present, the simple addition of the correlation functions for the various phases in proportion to their concentrations within the system is not valid, except in the case of the completely phase-separated system. The overall correlation function must reflect the boundaries between the various phases within the system. The cross correlation functions between the phases have a dependence both on the degree of mixing of the phases and also on the sizes of the domains of the phases. The correlation function for a non-crystalline solid with more than one phase has been derived in a general way. Particular application has been made to non-crystalline carbon for which the correlation function given previously did not have the correct limits because of absence of the cross correlation terms.     

The binaural performance of a cross-talk cancellation system with matched or mismatched setup and playback acoustics

Cross-talk cancellation is a method for synthesizing virtual auditory space using loudspeakers. One implementation is the "Optimal Source Distribution" technique [T. Takeuchi and P. Nelson, J. Acoust. Soc. Am. 112, 2786-2797 (2002)], in which the audio bandwidth is split across three pairs of loudspeakers, placed at azimuths of +/-90 degrees, +/-15 degrees, and +/-3 degrees, conveying low, mid, and high frequencies, respectively. A computational simulation of this system was developed and verified against measurements made on an acoustic system using a manikin. Both the acoustic system and the simulation gave a wideband average cancellation of almost 25 dB. The simulation showed that when there was a mismatch between the head-related transfer functions used to set up the system and those of the final listener, the cancellation was reduced to an average of 13 dB. Moreover, in this case the binaural interaural time differences and interaural level differences delivered by the simulation of the optimal source distribution (OSD) system often differed from the target values. It is concluded that only when the OSD system is set up with "matched" head-related transfer functions can it deliver accurate binaural cues.     

The promotion of d-type ions during the low energy collision-induced dissociation of some cysteic acid-containing peptides

Low energy collisionally activated dissociations (CAD) of doubly protonated peptides incorporating cysteic acid and arginine residues have been studied. Deuterium labeling experiments have established that loss of the elements of H₂SO₃ occurs with cleavage of one CH bond and transfer of the hydrogen to a neutral fragment. Prominent d-type ions were observed corresponding to cleavage at the cysteic acid residue. The analysis of structural analogs suggested that the unexpectedly low energy requirement for this process is attributable to a charge-proximal process promoted by intra-ionic interaction of the arginine and cysteic acid side chains. CAD (in the collision hexapole of a tandem quadrupole instrument) of electrospray source-formed fragment ions established that the d-type ions can form via b-type ions; there was no evidence of formation via (a _n + 1) or (b _n — H₂SO₃) ions. The equivalent d-ion was observed, albeit with lesser abundance, when the cysteic acid residue was replaced by aspartic acid, but not by glutamic acid.     

Minimum spectral contrast for vowel identification by normal-hearing and hearing-impaired listeners

To determine the minimum difference in amplitude between spectral peaks and troughs sufficient for vowel identification by normal-hearing and hearing-impaired listeners, four vowel-like complex sounds were created by summing the first 30 harmonics of a 100-Hz tone. The amplitudes of all harmonics were equal, except for two consecutive harmonics located at each of three "formant" locations. The amplitudes of these harmonics were equal and ranged from 1-8 dB more than the remaining components. Normal-hearing listeners achieved greater than 75% accuracy when peak-to-trough differences were 1-2 dB. Normal-hearing listeners who were tested in a noise background sufficient to raise their thresholds to the level of a flat, moderate hearing loss needed a 4-dB difference for identification. Listeners with a moderate, flat hearing loss required a 6- to 7-dB difference for identification. The results suggest, for normal-hearing listeners, that the peak-to-trough amplitude difference required for identification of this set of vowels is very near the threshold for detection of a change in the amplitude spectrum of a complex signal. Hearing-impaired listeners may have difficulty using closely spaced formants for vowel identification due to abnormal smoothing of the internal representation of the spectrum by broadened auditory filters.     

A mechanism for the loss of 60 u from peptides containing an arginine residue at the C-terminus

The loss of 60 u from protonated peptide ions containing an arginine residue at the C-terminus has been investigated by means of low energy tandem mass spectrometry. The lowest energy conformation of singly charged bradykinin is thought to involve a salt-bridge structure, which may lead to the formation of two isomeric forms. It is thought that one isomer retains the ionizing proton at the C-terminal end of the peptide, leading to the formation of the [b _n?1 + H + OH]⁺ fragment ion, and the other isomer retains the charge at the N-terminus, leading to the formation of the [M + H ? 60]⁺ fragment ion. It was found that the formation of the [M + H ? 60]⁺ ion occurs only from singly charged precursor ions. In addition, the loss of 60 u occurs from peptides in which the charge is localized at the N-terminus. These results indicate that the mechanism of formation of the [M + H ? 60]⁺ ion may be driven by a charge-remote process.