排序方式: 共有12条查询结果,搜索用时 218 毫秒
1.
M. V. Solovskii M. Yu. Eropkin E. M. Eropkina A. V. Slita M. Yu. Smirnova E. N. Vlasova E. B. Tarabukina A. I. Amirova 《Russian Journal of Applied Chemistry》2007,80(10):1703-1707
Nontoxic water-soluble low-molecular-weight (MW 14 000–36 000 Da) copolymers of acrylamide with 2-acrylamido-2-methylpropanesulfonic
acid, containing from 17.3 to 37.6 mol % sulfonate-containing monomeric units, were synthesized by heterophase radical polymerization
in isopropanol or ethanol at 50°C with azobis(isobutyronitrile) as an initiator.
Original Russian Text M.V. Solovskii, M.Yu. Eropkin, E.M. Eropkina, A.V. Slita, M.Yu. Smirnova, E.N. Vlasova, E.B. Tarabukina,
A.I. Amirova, 2007, published in Zhurnal Prikladnoi Khimii, 2007, Vol. 80, No. 10, pp. 1674–1678. 相似文献
2.
Viktor A. Dmitriev Mariia M. Efremova Alexander S. Novikov Vladimir V. Zarubaev Alexander V. Slita Anastasia V. Galochkina Galina L. Starova Andrey V. Ivanov Alexander P. Molchanov 《Tetrahedron letters》2018,59(24):2327-2331
The reactions of various nitrones with indolyl- and pyrrolylacrylates proceeds regioselectively with high diastereoselectivity in the case of aldonitrones, and represents an effective method for obtaining new indolyl- and pyrrolyl-substituted isoxazolidine carboxylates stabilized by weak (CH?O) and moderate (NH?N) strength intramolecular hydrogen bonding. The resulting cycloadducts exhibit promising in vitro anti-influenza activities. 相似文献
3.
Xin Zhang S. Ercelen V. E. Tikhonov S. Z. Karaeva A. V. Slita V. V. Zarubaev Y. Mély G. Duportail V. G. Babak 《Russian Journal of General Chemistry》2008,78(5):1093-1102
Low molecular weight chitosans (5 kDa) hydrophobically modified with 3, 10, and 18 mol % of tetradecenoyl (TDC) groups have been synthesized. Their good solubility at neutral pH, their surface activity and micelle-forming properties as well as their ability to interact with negatively charged phospholipid vesicles mimicking the internal layer of cell plasma membranes, allow us to consider them as potential non-viral transfection vectors for gene therapy. 相似文献
4.
Vorozhtsov Nikolai O. Yarovaya Olga I. Roznyatovskii Vitalii A. Tarasevich Boris N. Kozlovskaya Yuliya A. Petkova Aneliya I. Slita Aleksander V. Sinegubova Ekaterina O. Zarubaev Vladimir V. Salakhutdinov Nariman F. Beloglazkina Elena K. 《Chemistry of Heterocyclic Compounds》2021,57(4):432-441
Chemistry of Heterocyclic Compounds - For the first time, convenient methods for the preparation of pyrazoline N-alkylidene salts based on terpene (camphor, camphorquinone, carvone) ketones, cage... 相似文献
5.
Alexander P. Molchanov Valentina M. Lukina Mariia M. Efremova Anna A. Muryleva Alexander V. Slita Vladimir V. Zarubaev 《合成通讯》2020,50(9):1367-1374
AbstractAdamantane-derived aldo- and ketonitrones react with maleimides giving corresponding isoxazolidines. In the case of aldonitrones reactions proceed giving the diastereomeric mixtures. The ratio of isomers is changing during the reaction process due to the reversibility of the cycloaddition reaction. The cytotoxic and virus-inhibiting activity against influenza virus was investigated for selected adducts. 相似文献
6.
Andreeva Olga V. Garifullin Bulat F. Zarubaev Vladimir V. Slita Alexander V. Yesaulkova Iana L. Saifina Liliya F. Shulaeva Marina M. Belenok Maya G. Semenov Vyacheslav E. Kataev Vladimir E. 《Molecular diversity》2021,25(1):473-490
Molecular Diversity - Based on the fact that a search for influenza antivirals among nucleoside analogues has drawn very little attention of chemists, the present study reports the synthesis of a... 相似文献
7.
Vafina G. F. Khanova M. D. Esaulkova Ya. L. Sinegubova E. O. Slita A. V. Zarubaev V. V. 《Chemistry of Natural Compounds》2021,57(2):323-326
Chemistry of Natural Compounds - Three new maleopimaric acid derivatives were synthesized. The antiviral activity of 14 synthesized maleopimaric acid derivatives was tested against influenza virus... 相似文献
8.
Alexey Bobtsov Nikolay Nikolaev Olga Slita 《应用数学和力学(英文版)》2007,28(7):893-900
Analytical conditions and practical methods of their realization are proposed to solve a problem of a command signal tracking for a nonlinear disturbed system.Non- linear disturbed plants consisting of linear dynamic block and nonlinear block in feedback are considered.Nonlinear part of the plant and disturbance are unknown and bounded. The paper illustrates a possibility of applications of proposed algorithms to control libra- tion angle of satellite. 相似文献
9.
O. V. Nazarova I. A. Nuretdinov A. V. Slita G. M. Pavlov N. P. Evlampieva L. S. Litvinova V. P. Gubskaya G. M. Fazleeva L. Sh. Berezhnaya A. P. Pronina O. I. Kiselev E. F. Panarin 《Russian Journal of Applied Chemistry》2005,78(12):1981-1986
Water-soluble methanofullerene and fulleropyrrolidine derivatives were synthesized by the reactions of methanofullerenes (MFs) and fulleropyrrolidines (FPs) with poly(N-vinylpyrrolidone) (PVP) bearing one terminal amino group. The products contain MF or FP covalently bound to the polymer, corresponding polymeric complexes, and unreacted PVP. Large aggregates of the polymeric MF and FP derivatives are found in aqueous solutions. The electrooptical properties of the products differ considerably from those of the initial polymer. The phosphorus-containing MF and FP derivatives are capable of cleaving the molecule of plasmid DNA. 相似文献
10.
Olga V. Andreeva Bulat F. Garifullin Vladimir V. Zarubaev Alexander V. Slita Iana L. Yesaulkova Alexandrina S. Volobueva Mayya G. Belenok Maria A. Mankova Liliya F. Saifina Marina M. Shulaeva Alexandra D. Voloshina Anna P. Lyubina Vyacheslav E. Semenov Vladimir E. Kataev 《Molecules (Basel, Switzerland)》2021,26(12)
A series of 1,2,3-triazolyl nucleoside analogues in which 1,2,3-triazol-4-yl-β-d-ribofuranosyl fragments are attached via polymethylene linkers to both nitrogen atoms of the heterocycle moiety (uracil, 6-methyluracil, thymine, quinazoline-2,4-dione, alloxazine) or to the C-5 and N-3 atoms of the 6-methyluracil moiety was synthesized. All compounds synthesized were evaluated for antiviral activity against influenza virus A/PR/8/34/(H1N1) and coxsackievirus B3. Antiviral assays revealed three compounds, 2i, 5i, 11c, which showed moderate activity against influenza virus A H1N1 with IC50 values of 57.5 µM, 24.3 µM, and 29.2 µM, respectively. In the first two nucleoside analogues, 1,2,3-triazol-4-yl-β-d-ribofuranosyl fragments are attached via butylene linkers to N-1 and N-3 atoms of the heterocycle moiety (6-methyluracil and alloxazine, respectively). In nucleoside analogue 11c, two 1,2,3-triazol-4-yl-2′,3′,5′-tri-O-acetyl-β-d-ribofuranose fragments are attached via propylene linkers to the C-5 and N-3 atoms of the 6-methyluracil moiety. Almost all synthesized 1,2,3-triazolyl nucleoside analogues showed no antiviral activity against the coxsackie B3 virus. Two exceptions are 1,2,3-triazolyl nucleoside analogs 2f and 5f, in which 1,2,3-triazol-4-yl-2′,3′,5′-tri-O-acetyl-β-d-ribofuranose fragments are attached to the C-5 and N-3 atoms of the heterocycle moiety (6-methyluracil and alloxazine respectively). These compounds exhibited high antiviral potency against the coxsackie B3 virus with IC50 values of 12.4 and 11.3 µM, respectively, although both were inactive against influenza virus A H1N1. According to theoretical calculations, the antiviral activity of the 1,2,3-triazolyl nucleoside analogues 2i, 5i, and 11c against the H1N1 (A/PR/8/34) influenza virus can be explained by their influence on the functioning of the polymerase acidic protein (PA) of RNA-dependent RNA polymerase (RdRp). As to the antiviral activity of nucleoside analogs 2f and 5f against coxsackievirus B3, it can be explained by their interaction with the coat proteins VP1 and VP2. 相似文献