Polyethylenimine (PEI)g-comb-poly(ethylene glycol)-transferrin(I): Tumor-targeted Vector for Gene Delivery In-vitro

A new vector, PEG as a core, low Mw PEI was grafted to PEG, and transferrin was conjugated the co-polymer to form PEI-g-PEG-transferrin1,2. NMR, FT-IR and TGA spectroscopy confirmed the structures of activated PEG and the final products. The MW of PEI-g-P…     

超疏水表面黏附性的研究进展

结合作者课题组的相关工作,简要地论述了超疏水表面固液黏附性的主要影响因素和评价标准,介绍了天然和人工仿生具有特殊黏附性超疏水表面的研究进展,包括超疏水高黏附表面、超疏水低黏附表面、可控黏附性超疏水表面、各向异性黏滞力超疏水表面、黏滞力响应性智能超疏水表面以及超亲/超疏水图案表面制备及运用.特别介绍了作者研究小组在仿生可控黏滞力超疏表面制备以及超亲/超疏水图案表面运用的研究.最后对具有特殊黏附性超疏表面的研究进行总结和展望.     

pH-sensitive polymer-assisted refolding of urea-denatured fibroblast growth factor

A pH-responsive polymer Eudragit S-100 has been found to assist in correct folding of FGF-2(fibroblast growth factor-2) denatured with 8 mol/L urea and 10 mmol/L dithiothreitol at pH 7.2.The refolding of FGF-2 was performed by directly diluting denatured FGF-2 into a refolding buffer containing Eudragit S-100.The ability of Eudragit S-100 to enhance protein refolding level was investigated using MTr method,fluorescence emission spectroscopy and reverse phase HPLC.On the other hand,the result shows the ab...     

一种新型的基于磁性液体的光纤Sagnac磁场传感器

提出一种使用磁性液体的新型光纤Sagnac磁场传感器.磁性液体具有磁致可变双折射效应和二向色性,在外加磁场作用下,液体中的磁性纳米粒子沿磁场方向结链规则排列,形成各向异性.将其制成液体薄膜,放入具有一段保偏光纤的Sagnac环中,使光纤Saganc干涉仪的正弦形状干涉光谱可随外磁场变化.光纤中传输光垂直经过磁性液体薄膜...     

Different operation states of soliton pulses in an erbium-doped fibre ring laser

We report on the experimental observation of soliton pulses in an erbium doped fibre ring laser. The passive mode-locking is achieved using the nonlinear polarization rotation technique. By adjusting the pump power and the intracavity polarization controllers, a normal soliton, a stable 8th harmonic mode-locked pulse and a noise-like pulse have been observed in our laser. The experimental results revealed that the noise-like pulse is not suitable for the optical telecommunication, and in order to obtain the stable harmonic mode-locked soliton, a strong unstable CW laser field is necessary to mediate global soliton interaction. The formation mechanism of the harmonic mode-locked pulse has also been analysed.     

A quasi-crystal model of collagen microstructure based on SHG microscopy

<正>Second harmonic generation(SHG) results from molecules which are polarized by an external electric field often provided by an intense laser beam.The polarizability depends on firstly the intrinsic structural properties of the substance and hence the second-order nonlinear susceptibility,and secondly the intensity and polarization direction of the incident light.The polarization characteristics of the beam are therefore of interest.In this letter,we discuss some considerations in SHG microscopy of collagen when the incoming beam is circularly polarized,and present some supporting results as well as a numerical analysis.We propose a quasi-crystal model of collagen microstructure in an effort to further our understanding on this protein.     

Nucleation field,reversal mechanism and coercivity paradox in two-phased magnetic nanosystem

The magnetic reversal mechanism has been determined within a micromagnetic model reliably for a two-phased magnetic nanosystem,with the formulae for nucleation fields derived analytically.It is found that the nucleation field HN decreases uniformly as the size of the soft phase Ls increases whereas it increases with the size of the hard phase Lh.The analysis shows that whilst the effect of Lh could be ignored in most cases,where the nucleation field is dominated by the Ls and the calculation could be signif...     

Modeling fluid–particle interaction in dilute-phase turbulent liquid–particle flow simulation

The present work examines the predictive capability of a two-fluid CFD model that is based on the kinetic theory of granular flow in simulating dilute-phase turbulent liquid–particle pipe flows in which the interstitial fluid effect on the particle fluctuating motion is significant. The impacts of employing different drag correlations and turbulence closure models to describe the fluid–particle interactions (i.e. drag force and long-range interaction) are examined at both the mean and fluctuating velocity l...