Visible-light-mediated one-pot efficient synthesis of 1-aryl-1H,3H-thiazolo[3,4-a]benzimidazoles: a metal-free photochemical approach in aqueous ethanol

Molecular Diversity - A new metal-free approach to construct medicinally valuable 1-aryl-1H,3H-thiazolo[3,4-a]benzimidazoles under visible light irradiation in aqueous ethanol medium at room...     

A metal-free visible light promoted three-component facile synthesis of 4-oxo-tetrahydroindoles in ethanol–water

A mild and efficient visible light–mediated one-pot multicomponent tandem approach to construct 4-oxo-tetrahydroindoles in ethanol–water medium at room temperature has been described. The characteristics of reported methodology are the utilization of visible light, an ideal source of energy to generate C C and C N bonds from commercially available substrates namely dimedone, phenacyl bromides, and amines. The presented protocol is highly compatible for developing 4-oxo-tetrahydroindole derivatives with improved selectivity and high yields. Moreover, metal-free synthesis, environmental friendly solvent, easy workup process, high atom economy, cost-effectiveness, short reaction time, and broad substratescope are the major advantages of reported protocol.