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Elham Moosazadeh Enayatollah Sheikhhosseini Dadkhoda Ghazanfari Shahla Soltaninejad 《Journal of heterocyclic chemistry》2020,57(5):2271-2278
In the present study, a group of polysubstituted furopyran derivatives possessing ether spacer groups were synthesized under good-to-exceptional yields via cycloaddition of bisarylidene Meldrum's acid derivatives (1 mmol) with isocyanides (6 mmol) within dichloromethane (CH2Cl2) for 3 to6 hours at room temperature with no assistance from any type of catalysts. The structure of the products was then confirmed by Fourier Transform-infrared spectroscopy, 1H-nuclear magnetic resonance spectroscopy, 13C-nuclear magnetic resonance spectroscopy, and elemental analysis. Moreover, the 5c , 5d , and 5f compounds exhibited favorable pharmaceutical behavior as antibacterial. 相似文献
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