排序方式: 共有78条查询结果,搜索用时 15 毫秒
1.
Yavolovskii A. A. Ivanov E. I. Mazepa A. V. Ivanov Yu. E. 《Russian Journal of General Chemistry》2003,73(9):1486-1488
[1,2,3]Triazolo[4,5-d]pyrimidine 3-oxides were synthesized by replacement of the amino group in 6-aminouracil by hydroxyamino, coupling of the resulting 6-hydroxyaminopyrimidine with benzenediazonium salts, and oxidation of 6-hydroxyamino-5-phenylazouracils with a solution of K3[Fe(CN)6] in water. 相似文献
2.
E. A. Alekseeva K. S. Andronati A. V. Mazepa A. I. Gren’ T. V. Pavlovskaya I. A. Kravchenko V. I. Bozhanov 《Russian Journal of General Chemistry》2006,76(9):1464-1467
A series of p-tert-butylcalix[4]arene derivatives containing 1,4(1,5)-benzodiazepinone fragments as substituents were prepared. The biological activity of the compounds, namely, their antispasmodic activity in mice, was evaluated by antagonism with a spasmodic agent, Corazol, upon transdermal administration. According to the data obtained, benzodiazepine derivatives of calixarenes show higher antispasmodic activity compared to 3-hydroxyphenazepam, taking into account their considerably higher molecular weight. 相似文献
3.
Lukyanenko NG Kirichenko TI Lyapunov AY Mazepa AV Simonov YA Fonari MS Botoshansky MM 《Chemistry (Weinheim an der Bergstrasse, Germany)》2004,11(1):262-270
The first three representatives of the new family of oxacyclophanes incorporating two 2,7-dioxyfluorenone fragments, connected by [-CH(2)CH(2)O-](m) spacers (m=2-4), have been synthesized. The yield of the smallest oxacyclophane (m=2) is considerably higher with respect to the larger ones (m=3 and m=4), which are formed in comparable yields. Molecular modeling and NMR spectra analysis of the model compounds suggest that an essential difference in oxacyclophanes yields is caused by formation of quasi-cyclic intermediates, which are preorganized for macrocyclization owing to intramolecular pi-pi stacking interactions between the fluorenone units. The solid-state structures of these oxacyclophanes exhibit intra- and intermolecular pi-pi stacking interactions that dictate their rectangular shape in the fluorenone backbone and crystal packing of the molecules with the parallel or T-shape arrangement. The crystal packing in all cases is also sustained by weak C--HO hydrogen bonds. FAB mass spectral analysis of mixtures of the larger oxacyclophanes (m=3 and m=4) and a paraquat moiety revealed peaks corresponding to the loss of one and two PF(6) (-) counterions from the 1:1 complexes formed. However, no signals were observed for complexes of the paraquat moiety with the smaller oxacyclophane (m=2). Computer molecular modeling of complexes revealed a pseudorotaxane-like incorporation of the paraquat unit, sandwiched within a macrocyclic cavity between the almost parallel-aligned fluorenone rings of the larger oxacyclophanes (m=3 and m=4). In contrast to this, only external complexes of the smallest oxacyclophane (m=2) with a paraquat unit have been found in the energy window of 10 kcal mol(-1). 相似文献
4.
Victor V. Dotsenko Arif I. Ismiev Anastasiya N. Khrustaleva Konstantin A. Frolov Sergey G. Krivokolysko Elena A. Chigorina Aleksey P. Snizhko Vladimir M. Gromenko Ivan S. Bushmarinov Rizvan K. Askerov Tatyana M. Pekhtereva Sergey Yu. Suykov Elena S. Papayanina Aleksandr V. Mazepa Abel M. Magerramov 《Chemistry of Heterocyclic Compounds》2016,52(7):473-483
5.
E. A. Alekseeva S. S. Basok I. M. Rakipov A. V. Mazepa A. I. Gren’ 《Russian Journal of Organic Chemistry》2013,49(7):1035-1041
Regardless of the reducing agent, the reduction at 25°C and higher of the amide groups in a large number of p-tert-butylcalix[4]arene derivatives containing amide fragments with different substituents on the nitrogen atoms was accompanied by hydrogenolysis of the C-N bond with formation of the corresponding O-(2-hydroxyethyl) calixarenes and by partial cleavage of the ether bond between the calixarene framework and the substituent to give compounds with a lower degree of substitution. 相似文献
6.
O. V. Kulikov V. I. Pavlovsky A. V. Mazepa S. A. Andronati 《Chemistry of Heterocyclic Compounds》2003,39(4):485-492
The chemical properties of 8,18-disubstituted 6,16-diphenyl-1,2,3,11,12,13-tetrahydrodibenzo[g,o]-4,14-dioxa-1,5,11,15-tetraazahexadecine-2,12-diones have been studied, including their interaction with N-nucleophiles (hydroxylamine, hydrazine, semicarbazide, and thiosemicarbazide), acidic and alkaline hydrolysis, and methylation. A hypothesis has been made from analysis of the mass spectral data of the thiosemicarbazide on the preferred existence of 6-substituted 4-phenylquinazoline-2-carbaldehydes in the gas phase as the linear tautomer. 相似文献
7.
Luk’yanenko N. G. Kirichenko T. I. Lyapunov A. Yu. Kulygina E. Yu. Mazepa A. V. 《Russian Journal of Organic Chemistry》2009,45(2):304-311
New crownophane family was synthesized containing fragments of 2,7-dioxyfluorenone and hydroquinone connected with residues of tri- and tetraethylene glycols. The formation of inclusion complexes of these ligands with paraquat was established by means of mass spectrometry (fast-atom bombardment), 1H NMR and electronic spectroscopy. The crownophane with a larger ring formed the more stable complex.
相似文献8.
A. S. Tolkunov V. N. Baumer G. V. Palamarchuk O. V. Shishkin A.V. Mazepa S. V. Tolkunov S. L. Bogza 《Chemistry of Heterocyclic Compounds》2011,47(8):1006-1013
A new strategy for the synthesis of the eight-membered heterocyclic skeleton of tetrahydro-quinazolino[3,2-c][2,3]benzodiazocin-15-ones, based on the Pictet–Spengler reaction of 3-amino-2-[2-(3,4-dimethoxyphenyl)ethyl]quinazolin-4(3H)-one with carbonyl compounds in acidic media, is proposed. 相似文献
9.
10.
Yu. A. Popkov E. A. Romanova A. V. Mazepa Yu. V. Korovin 《Chemistry of Heterocyclic Compounds》1996,32(2):229-232
A method was developed for preparing bi- and tricyclic tetra- and hexaazamacrocycles using the reaction of 1, 4, 7,10-tetraazacyclododecane with various alkylating ditosylates.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 255–258, February, 1996. 相似文献