排序方式: 共有44条查询结果,搜索用时 15 毫秒
1.
Salinas-Nolasco MF Méndez-Vivar J Lara VH Bosch P 《Journal of colloid and interface science》2004,274(1):16-24
Samples of polycrystalline calcite were impregnated with solutions of malonic acid of three concentrations (5 x 10(-2), 5 x 10(-3) , and 5 x 10(-4) M) and different pH values (6.00, 7.00, and 8.00). The impregnation was carried out at room temperature to evaluate the adsorption of malonate ion in the calcite surface to optimize the conditions for possible application on limestone and marble in cultural heritage materials. The affinity of the malonate ion was determined through the potentiometric measurement of the surface charge and the corresponding adsorbed amounts by titration, Raman spectroscopy, and small-angle X-ray scattering (SAXS). The results indicate effective adsorption of the malonate ion on the surface at a pH value close to the point of zero charge (pHpzc approximately 8.20) and changes in some surface morphological properties such as the pore shape and the pore size distribution. The presence of a malonate adsorptive layer on calcite generates an interface interaction potential that may influence the reaction and transport mechanisms within the medium. 相似文献
2.
Boseggia E Gatos M Lucatello L Mancin F Moro S Palumbo M Sissi C Tecilla P Tonellato U Zagotto G 《Journal of the American Chemical Society》2004,126(14):4543-4549
A series of cis-cis-triaminocyclohexane Zn(II) complex-anthraquinone intercalator conjugates, designed in such a way to allow their easy synthesis and modification, have been investigated as hydrolytic cleaving agents for plasmid DNA. The ligand structure comprises a triaminocyclohexane platform linked by means of alkyl spacers of different length (from C(4) to C(8)) to the anthraquinone group which may intercalate the DNA. At a concentration of 5 microM, the complex of the derivative with a C(8) alkyl spacer induces the hydrolytic stand scission of supercoiled DNA with a rate of 4.6 x 10(-6) s(-1) at pH 7 and 37 degrees C. The conjugation of the metal complex with the anthraquinone group leads to a 15-fold increase of the cleavage efficiency when compared with the anthraquinone lacking Zn-triaminocyclohexane complex. The straightforward synthetic procedure employed, allowing a systematic change of the spacer length, made possible to gain more insight on the role of the intercalating group in determining the reactivity of the systems. Comparison of the reactivity of the different complexes shows a remarkable increase of the DNA cleaving efficiency with the length of the spacer. In the case of too-short spacers, the advantages due to the increased DNA affinity are canceled due to the incorrect positioning of the reactive group, thus leading to cleavage inhibition. 相似文献
3.
Giuseppe Werber Francesco Buccheri Nicol Vivona Manlio Gentile 《Journal of heterocyclic chemistry》1978,15(8):1393-1398
The factors influencing the reactivity of α-thienylglyoxal monosemicarbazones when treated with cyclizing reagents (bromine/sodium acetate and hydrobromic acid in acetic acid) were investigated. Depending on the experimental conditions, on the position of the substituent on the semicarbazide residue, and on the cyclizing agent, the substrates 1a-e give the semicarbazone bromides 2a-b, 5 , the 1,3,4-oxadiazoles 3a-c , the 1,2,4-triazine 11 and the 2,3,4,5-tetrahydro-1,2,4-triazine-3-ones 6, 8 and 9 . Compound 6 by thermolysis undergoes ring contraction in the Δ2-1,3,4-oxadiazoline 12 , while treatment with base involves the conversion of 6 into 1,2,4-triazol-5-one 13 . Ir, nmr and mass spectra support the reported structures. 相似文献
4.
Giuseppe Werber Francesco Buccheri Manlio Gentile 《Journal of heterocyclic chemistry》1977,14(7):1263-1265
The ambident nucleophilic behaviour of some 2-amino-5-H-1,3,4-thiadiazoles in alkylation, acylation and nitrosation reaction has been verified. The structures assigned to the 2-amino-1,3,4-thiadiazoles ( 1a-i ) and to the Δ2-1,3,4-thiadiazolines ( 2a-e ) agree with the spectral data. 相似文献
5.
Annabella Astorino Antonio Fuduli Manlio Gaudioso 《Computational Optimization and Applications》2012,53(2):301-322
We face the problem of strictly separating two sets of points by means of a sphere, considering the two cases where the center of the sphere is fixed or free, respectively. In particular, for the former we present a fast and simple solution algorithm, whereas for the latter one we use the DC-Algorithm based on a DC decomposition of the error function. Numerical results for both the cases are presented on several classical binary datasets drawn from the literature. 相似文献
6.
Jorge‐Aarn Rangel‐Mndez Manlio‐Joaquin Graniel‐Sabido Juan‐Francisco Snchez‐Cruz Rosa Moo‐Puc 《Biomedical chromatography : BMC》2019,33(4)
To date, several methods for the quantification of tamoxifen and its metabolites have been developed, most of which employ liquid chromatography tandem–mass spectrometry (LC–MS/MS). These methods are highly sensitive and reproducible, but are also time‐consuming and require expensive equipment; one of their main disadvantages is matrix ionization effects. A more viable option, particularly in developing countries, is high‐performance liquid chromatography coupled with UV or fluorescence detection. We developed and validated a method for simultaneous quantification of tamoxifen, endoxifen and 4‐hydroxytamoxifen based on high‐performance liquid chromatography with fluorescence detection in a reverse‐phase column. The method is rapid (16 min plus 5 min of column re‐equilibrium), accurate (80–100%) and precise (0.23–6.00%), and does not require any additional irradiation process. Sample pretreatment consists of protein precipitation with acetonitrile under alkaline conditions, employing only 200 μL plasma. The validated method's wide range allowed quantification of steady‐state levels in patients under standard tamoxifen treatment (20 mg/day). This assay is ready for application in clinical studies and routine quantification of tamoxifen, endoxifen and 4‐hydroxytamoxifen in healthcare institutions. 相似文献
7.
We get estimates on the eigenvalues of the Kählerian Dirac operator in terms of the eigenvalues of the scalar Laplace–Beltrami operator. In odd complex dimension, these estimates are sharp, in the sense that, for the first eigenvalue, they reduce to Kirchberg's inequality. 相似文献
8.
9.
Manlio Pisa 《Colloid and polymer science》1933,63(2):139-148
Ohne Zusammenfassung
Es sei mir gestattet, Herrn Professor Dr. H. Bechhold für sein stetiges Interesse an dieser Untersuchung bestens zu danken.
Ebenso habe ich Herrn Dr. H. Karplus für viele Anregungen und Herrn Dr. F. Erbe für seine Hilfe bei der experimentellen Ausführung
und bei der Abfassung dieser Arbeit meinen Dank auszusprechen. 相似文献
10.
Annabella Astorino Manlio Gaudioso Alberto Seeger 《Journal of Global Optimization》2014,58(4):729-750
Let $\{a_i:i\in I\}$ be a finite set in $\mathbb R ^n$ . The illumination problem addressed in this work is about selecting an apex $z$ in a prescribed set $Z\subseteq \mathbb R ^n$ and a unit vector $y\in \mathbb R ^n$ so that the conic light beam $$\begin{aligned} C(z,y,s):= \{x \in \mathbb R ^n : s\,\Vert x-z\Vert - \langle y, x-z\rangle \le 0\} \end{aligned}$$ captures every $a_i$ and, at the same time, it has a sharpness coefficient $ s\in [0,1]$ as large as possible. 相似文献