电渗流与缓冲液浓度之间数学关系的线性表达

It was believed that electroosmotic mobility μeo is inversely proportional to the square root of the ionic strength L But the linear relationship for regression analysis was expressed differently in different papers. The paper studied the linear expression of the mathematical relationship between μeo and c （background buffer concentration） by mathematical transform and real experimental data.μeo values of fused silica capillary were determined in four buffer systems. Their experimental conditions were controlled carefully for decreasing temperature difference AT and pH difference ApH in 50 μm ID capillary, in which no double layer overlap existed. The linear relationship between the reciprocal of electroosmotic mobility and the square root of concentration （or ionic strength） was derived by mathematical method. The regression analysis of experimental data was shown to well correspond to the relationship. The constants in regression equation could be well defined and the calculated results were acceptable.     

Multistrain edge‐based compartmental model on networks

Multistrain diseases, which are infected through individual contacts, pose severe public health threat nowadays. In this paper, we build competitive and mutative two‐strain edge‐based compartmental models using probability generation function (PGF) and pair approximation (PA). Both of them are ordinary differential equations. Their basic reproduction numbers and final size formulas are explicitly derived. We show that the formula gives a unique positive final epidemic size when the reproduction number is larger than unity. We further consider competitive and mutative multistrain diseases spreading models and compute their basic reproduction numbers. We perform numerical simulations that show some dynamical properties of the competitive and mutative two‐strain models.     

Effects of rainfall infiltration on deep slope failure

With the finite element method and the limit equilibrium method, a numerical model has been established for examining the effects of rainfall infiltration on the stability of slopes. This model is able to availably reflect the variations in pore pressure field in slopes, dead weight of soil, and the softening of soil strength caused by rainfall infiltration. As a case study, an actual landslide located at the Nongji Jixiao in Chongqing is studied to analyze the effects of rainfall infiltration on the seepage field and the slope stability. The simulated results show that a deep slope failure is prone to occur when rainfall infiltration will lead to a remarkable variation in the seepage field, in particular, for large range pore water pressure increase in slopes. Supported by the Knowledge Innovation Project of Chinese Academy of Sciences (Grant No. KJCX2-SW-L1-4) and the Major State Basic Research Development Program of China (Grant No. 2002CB412703)     

定量核磁共振波谱法同时测定中药虎杖中白藜芦醇和虎杖苷的含量

建立了定量核磁共振波谱法同时测定虎杖中白藜芦醇和虎杖苷的方法。样品用80%乙醇和丙酮两次超声提取净化,再用定量核磁共振波谱法测定。考察了样品预处理和核磁共振实验条件对测定结果的影响,选择氘代二甲亚砜-重水(10∶1,V/V)为溶剂,用基准物质邻苯二甲酸氢钾标定的2,3,5-三碘苯甲酸为内标,选择脉冲延迟时间为5 s,采样次数为32次。定量峰为6.388~6.391(白藜芦醇:H-2,6,d,2H)和6.322~6.330(虎杖苷:H-4,t,1H)。结果表明,NMR测定的精密度均小于0.6%,线性相关系数(r)均大于0.999,白藜芦醇和虎杖苷的检出限分别为0.23和0.24 g/L,定量限分别为0.69和1.57 g/L,包括样品提取过程的回收率分别为97.7%~103.5%(RSD=2.4%)和94.5%~99.2%(RSD=1.6%),显示出定量核磁共振法在中药定量时的可靠性。实际测定4种虎杖饮片及配方颗粒样品中白藜芦醇和虎杖苷含量分别为3.57~5.69 mg/g和12.73~24.07 mg/g。     

Studies of the structural,electronic and dielectric properties of Ca1−xSrxTiO3

The lattice constants, band structure and dielectric properties of Ca_1−xSr_xTiO₃ (0<x<1) (CSTO) have been studies by using the first-principles implemented with the GGA-PBEsol method. The calculation results shows that the lattice constants of CSTO obeys the Vegard model while the energy gap of CSTO shows a decreasing trend with the changing molar fraction x. The real and imaginary parts of the dielectric function and the static dielectric constant of the CSTO, optical permittivity and the static refractive index, are given to support the potential applications of the compounds in the future.     

毒莠定印迹邻氨基苯硫酚/金纳米粒子复合膜安培传感器

在模板分子存在下,在金电极上自组装邻氨基苯硫酚（oATP）,通过电聚合制得毒莠定印迹的oATP/金纳米粒子聚合薄膜及其安培传感器.采用循环伏安法和交流阻抗技术对传感器制备过程进行表征,用紫外光谱法研究了单体与模板间的相互作用.以K3Fe（CN）6为探针,示差脉冲伏安曲线的峰电流与毒莠定浓度在2.0×10^-7-2.4×10 4mol/L范围内呈现良好的线性关系（r=0.9963）,毒莠定的检出限为6.5×10 8mol/L（S/N=3）.将该印迹膜传感器用于环境水样加标回收检测,结果令人满意.     

核酸碱基的非谐性振动:正规及错配碱基对的一维和二维红外光谱及其结构基础

用量子化学计算研究了正规Watson-Crick碱基对和四例典型的错配碱基对.对碱基单体和二聚体进行了详细的非谐性频率分析,以揭示其结构方面的一些振动特征.研究发现这些振动特征能在模拟的一维和二维红外光谱中很好地表现出来.利用势能分布研究了所选简正模式的离域化程度,发现从孤立的碱基单体到参与氢键的二聚体,模式的离域化程度变化很大;同时,这些模式的非谐性常数也发生了相应的改变.以人们通常认为的位于红外光谱中6-μm波长区域的羰基伸缩模式为例进行了探讨.     

表面光接枝聚合反应新进展

表面性能对高分子材料应用至关重要,但多数聚烯烃材料表面惰性,需对表面进行改性或功能化．紫外光引发表面光接枝聚合反应具有诸多优势,因而获得广泛应用．作者以本实验室近年的研究为基础,结合这一领域国际上的部分重要研究成果,概述了实施表面光接枝聚合反应的一些新方法：控制,活性表面光接枝聚合、自引发光接枝聚合、暗区表面光接枝聚合、表面光接枝-交联聚合以及表面小分子光化学反应等．     

Multi-life cycles utilization of retired satellites

Retired geosynchronous (GEO) communication satellites affect the GEO orbit environment in outer space. According to the new concept of modern design, the authors propose creatively a method of reusing retired GEO communication satellites, through adjusting retired GEO satellites to slightly inclined orbit geosynchronous (SIGSO) satellites. After these retired satellites are applied to the navigation and communication system, integrity of navigation system and positioning accuracy of the system is improved. Meanwhile, some transponders on these retired satellites can be used to establish a new satellite communication service, and initiate the study and utilization of the multi-life cycle for retired satellites. Experimental results show that this project has significant social value and can make remarkable economic benefit. Supported by the National Basic Research and Development Program of China (Grant No. 2007CB815501) and the National High Technology Research and Development Program of China (Grant No. 2007AA12z343)     

Study on the drug resistance and the binding mode of HIV-1 integrase with LCA inhibitor

Human immunodeficiency virus type 1 (HIV-1) integrase (IN) is an essential enzyme in the lifecycle of this virus and also an important target for the study of anti-HIV drugs. The binding mode of the wild type IN core domain and its G140S mutant with L-Chicoric acid (LCA) inhibitor were investigated by using multiple conformation molecular docking and molecular dynamics (MD) simulation. Based on the binding modes, the drug resistance mechanism was explored for the G140S mutant of IN with LCA. The results indicate that the binding site of the G140S mutant of IN core domain with LCA is different from that of the core domain of the wild type IN, which leads to the partial loss of inhibition potency of LCA. The flexibility of the IN functional loop region and the interactions between Mg2 ion and the three key residues (i.e., D64, D116, E152) stimulate the biological operation of IN. The drug resistance also lies in several other important effects, such as the repulsion between LCA and E152 in the G140S mutant core domain, the weakening of K159 binding with LCA and Y143 pointing to the pocket of the G140S mutant. All of the above simulation results agree well with experimental data, which provide us with some helpful information for designing the drug of anti-HIV based on the structure of IN.