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Christian Grieser Ingo G. Steffen Daniel Seehofer Incken-Birthe Kramme Robert Uktolseya Christian Scheurig-Muenkler Bernd Hamm Timm Denecke 《Magnetic resonance imaging》2013
Purpose
The purpose of this study was to evaluate enhancement characteristics of histopathologically confirmed focal nodular hyperplasia (FNHs) with gadoxetic acid-enhanced MRI.Materials and Methods
Twenty-seven patients with all histopathologically proven FNHs were retrospectively identified. MRI consisted of T1- and T2-weighted (w) sequences with and without fat saturation (FS), multiphase dynamic T1-w images, and FS T1-w images during the hepatobiliary phase. Standard of reference was surgical resection (n = 24) or biopsy (n = 3). Images were analyzed for morphology and contrast behavior including signal intensity (SI) measurement on T1-w images normalized to the pre-contrast base line.Results
In total 36 FNHs were evaluated. All FNHs showed enhancement in the arterial phase, significant reduction contrast enhancement (“wash-out”) in the late dynamic phases was not present. In the hepatobiliary phase, all FNHs (100%) showed enhancement (overall SI increase, 118% (± 91%), P < 0.001) with at least partial hyperintensity to the liver. Upon visual comparison, 3 of 36 FNHs appeared with heterogeneous/partial enhancement (8%) and 7 (19%) showed rim-accentuated enhancement.Conclusion
The typical enhancement pattern of FNH with gadoxetic acid consists of arterial hyperperfusion, no wash-out during the venous phase, and at least partial hyperintensity compared to the liver in the hepatobiliary phase. Partial hypointensity or rim-accentuated enhancement rarely occurs. 相似文献2.
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Franz X. Effenberger Roland Kramme Hans Jörg Lindner Georg Martin Hans-Dieter Martin Bernhard Mayer 《欧洲无机化学杂志》1991,124(4):827-832
Chromophoric Systems, 2. – Conformation and Absorption of Light in (2-Alkoxyvinyl)ethanediones The unusual color properties of yellow 1,2-bis(4,5-dihydrofuran-3-yl)ethane-1,2-dione ( 1 ) and colorless 1,2-bis(5,6-dihydro-4H-pyran-3-yl)ethane-1,2-dione ( 2 ) in the solid state and in solution are investigated by crystal structure analysis, UV-Vis, PE, and 13C-NMR spectroscopy as well as by reparameterized force-field calculations. Dione 1 takes an antiperiplaner CO/CO conformation of its chromophore in the solid state whereas dione 2 is twisted in this respect by 102°. In solution both chromophores are not planar, but 1 is less distorted (ca. 142°) than dione 2 (ca. 126°). The calculated rotational barrier for CO/CO twisting amounts to 0.9 kcal mol−1 for 1 and to 2.2 kcal mol−1 for 2 . 相似文献
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